Hematologic Malignancy
Acute Lymphoblastic Leukemia
CI-CAN-00000400ALLExplore in graph →
Hematologic546 active trials12 approved drugs43 evidence items
- NCIt
- C3167
- DOID
- 9952
- MeSH
- D054198
- Other
- 3 more codes
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Hematologic Malignancy
CI-CAN-00000400ALLExplore in graph →
Clinical trials
2,037 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (268)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT06249880 | Pediatric Normative Markerless Movement Analysis | recruiting | — | 40 | MultiCare Health System Research InstituteOTHER | 1 | Mar 9, 2026 | clinicaltrials |
| NCT06326008 | Safety, Tolerability, and Pharmacokinetics of Donor-derived CD19 CAR Therapy Bridged Allo-HSCT and Sequential Donor-derived CD22 CAR Therapy for r/r B-ALL: a Clinical Trial | recruiting | Phase 1 | 48 | Beijing GoBroad HospitalOTHER | 1 | Mar 9, 2026 |
| clinicaltrials |
| NCT05306301 | Ponatinib Plus Chemotherapy in Acute Lymphoblastic Leukemia Patients | active not recruiting | Phase 2 | 32 | Gruppo Italiano Malattie EMatologiche dell'AdultoOTHER | 1 | Mar 6, 2026 | clinicaltrials |
| NCT05581030 | CalPeg for Newly Diagnosed Acute Lymphoblastic Leukemia (ALL) | recruiting | Phase 1 | 7 | H. Lee Moffitt Cancer Center and Research InstituteOTHER | 1 | Mar 6, 2026 | clinicaltrials |
| NCT06253637 | Daratumumab in VHR T-ALL Treated According to the ALL National Treatment Program(DARATALL-VHR) | active not recruiting | Phase 2 | 31 | Gruppo Italiano Malattie EMatologiche dell'AdultoOTHER | 1 | Mar 5, 2026 | clinicaltrials |
| NCT06575296 | Revumenib for the Treatment of Acute Leukemia in Patients Post-Allogeneic Stem Cell Transplant | recruiting | Phase 1 | 27 | City of Hope Medical CenterOTHER | 1 | Mar 5, 2026 | clinicaltrials |
| NCT05316701 | Precision-T: A Randomized Study of Orca-T in Recipients Undergoing Allogeneic Transplantation for Hematologic Malignancies(Orca-T) | active not recruiting | Phase 3 | 187 | Orca Biosystems, Inc.INDUSTRY | 1 | Mar 4, 2026 | clinicaltrials |
| NCT04794296 | Recommendations for the Treatment of Children With Acute Lymphoblastic Leukemia in the GFAOP(LALGFA2019) | recruiting | — | 500 | French Africa Pediatric Oncology GroupOTHER | 3 | Mar 2, 2026 | clinicaltrials |
| NCT06481228 | Efficacy and Safety of TKI Combined With Chemotherapy and Sequential CAR-T Cells in ND Adult Patients With Ph+ ALL | recruiting | N/A | 82 | Institute of Hematology & Blood Diseases Hospital, ChinaOTHER | 1 | Mar 2, 2026 | clinicaltrials |
| NCT06481241 | Efficacy and Safety of Chemotherapy Combined With CAR-T Cells in Newly Diagnosed Adult Patients With Ph- B-ALL | recruiting | N/A | 77 | Institute of Hematology & Blood Diseases Hospital, ChinaOTHER | 1 | Mar 2, 2026 | clinicaltrials |
| NCT07443592 | Treatment for Ph-negative ALL for Adults up to 65 Years(LAL-2025) | not yet recruiting | N/A | 330 | PETHEMA FoundationOTHER | 1 | Mar 2, 2026 | clinicaltrials |
| NCT06367725 | Pharmacokinetics of Dexamethasone in Childhood ALL and Reduction in Bone Mineral Density | recruiting | — | 100 | University of AarhusOTHER | 1 | Feb 27, 2026 | clinicaltrials |
| NCT07441291 | CD19 CAR-T vs DLI for Post-HSCT MRD in Ph- ALL: A RCT | recruiting | Phase 3 | 70 | Peking University People's HospitalOTHER | 1 | Feb 27, 2026 | clinicaltrials |
| NCT06052813 | A Study of BN104 in the Treatment of Acute Leukemia | active not recruiting | Phase 1 / Phase 2 | 66 | Institut de Recherches Internationales Servier (I.R.I.S.)INDUSTRY | 1 | Feb 25, 2026 | clinicaltrials |
| NCT06389305 | CIK Cell Therapy for Relapsed or Refractory Acute B-Lymphoblastic Leukemia: Prognostic Impact on Patients With Early CAR-T Cell Dysfunction | recruiting | N/A | 213 | Beijing GoBroad HospitalOTHER | 1 | Feb 25, 2026 | clinicaltrials |
| NCT07422337 | A Multi-site Study to Evaluate the Persistence of Protective Immunity to Routine Childhood Vaccinations in Participants With B-ALL/Ly Who Have Received Blinatumomab(BOOSTER) | recruiting | — | 300 | Arkansas Children's Hospital Research InstituteOTHER | 1 | Feb 25, 2026 | clinicaltrials |
| NCT07429461 | Clinical Study of SYNCAR-100 in the Treatment of Relapsed/Refractory Acute B-Lymphoblastic Leukemia | recruiting | Early Phase 1 | 16 | Zhejiang UniversityOTHER | 1 | Feb 24, 2026 | clinicaltrials |
| NCT03042221 | Early Rebiopsy to Identify Biomarkers of Tumor Cell Survival Following EGFR, ALK, ROS1 or BRAF TKI Therapy | recruiting | — | 100 | University of Colorado, DenverOTHER | 1 | Feb 20, 2026 | clinicaltrials |
| NCT06863259 | Study of Inotuzumab Ozogamicin, Venetoclax, and Dexamethasone for Relapsed B-cell ALL | recruiting | Phase 1 | 28 | Children's Hospital Medical Center, CincinnatiOTHER | 1 | Feb 18, 2026 | clinicaltrials |
| NCT04512716 | Iomab-ACT: A Pilot Study of 131-I Apamistamab Followed by CD19-Targeted CAR T-Cell Therapy for Patients With Relapsed or Refractory B-Cell Acute Lymphoblastic Leukemia or Diffuse Large B-Cell Lymphoma | recruiting | Early Phase 1 | 12 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | Feb 17, 2026 | clinicaltrials |
| NCT07203742 | The Effect of Mandala on Anxiety and Fear Levels in Children With Leukemia Before Intrathecal Chemotherapy Treatment | recruiting | N/A | 60 | Ege UniversityOTHER | 1 | Feb 17, 2026 | clinicaltrials |
| NCT07403630 | INTEGRATIVE "MULTI-OMICS" AND FUNCTIONAL PLATFORM FOR THE COMPLETE DIAGNOSTIC CHARACTERIZATION OF TUMORS: THE ITALIAN TUMOR CHEMOGENOMIC PROFILER (IT-TCP)(IT-TCP POS) | recruiting | N/A | 300 | Azienda Ospedaliero-Universitaria di ParmaOTHER | 1 | Feb 17, 2026 | clinicaltrials |
| NCT07071051 | Exploring the Effect of Calaspargase Pegol on the Coagulation System in Pediatric Acute Lymphoblastic Leukemia (ALL) Patients: Pilot Study | recruiting | — | 15 | Mayo ClinicOTHER | 1 | Feb 13, 2026 | clinicaltrials |
| NCT06991920 | Immune-targeted Combination With Chemotherapy for Acute Leukemia of Ambiguous Lineage | not yet recruiting | N/A | 50 | Institute of Hematology & Blood Diseases Hospital, ChinaOTHER | 0 | Feb 11, 2026 | clinicaltrials |
| NCT06287528 | A Study of 19-28z/IL-18 in People With Acute Lymphoblastic Leukemia (ALL) | recruiting | Phase 1 | 18 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | Feb 10, 2026 | clinicaltrials |
| NCT06860269 | A 3-cohort Randomized Study Evaluating the Role of New Immunotherapeutic Agents and of Allogeneic Hematopoietic Stem Cell Transplantation (HSCT) in Frontline Therapy of Adults With Acute Lymphoblastic Leukemia(GRAALL-2024) | recruiting | Phase 2 / Phase 3 | 1,200 | Assistance Publique - Hôpitaux de ParisOTHER | 1 | Feb 10, 2026 | clinicaltrials |
| NCT03938987 | Anti-CD19, Dual Co-stimulatory (4-1BB, CD3ζ) Chimeric Antigen Receptor T-cells in Patients With Relapsed/Refractory Aggressive Lymphoma or Acute Lymphoblastic Leukemia (ALL)(ACIT001/EXC002) | recruiting | Phase 1 / Phase 2 | 63 | University of AlbertaOTHER | 1 | Feb 9, 2026 | clinicaltrials |
| NCT00586391 | CD19 Chimeric Receptor Expressing T Lymphocytes In B-Cell Non Hodgkin's Lymphoma, ALL & CLL(CRETI-NH) | active not recruiting | Phase 1 | 14 | Baylor College of MedicineOTHER | 1 | Feb 6, 2026 | clinicaltrials |
| NCT06580301 | Study of YK012 in B-cell Acute Lymphoblastic Leukemia | recruiting | Phase 1 / Phase 2 | 46 | Excyte Biopharma LtdINDUSTRY | 1 | Feb 6, 2026 | clinicaltrials |
| NCT04575883 | HIIT in Youth With Congenital Heart Disease (MedBIKE) | recruiting | N/A | 44 | University of AlbertaOTHER | 1 | Feb 5, 2026 | clinicaltrials |
| NCT05366218 | Tafasitamab (MOR00208) in Pediatric Patients With Relapsed or Refractory Acute B Lineage Leukemia(Anti-CD19-ALL) | recruiting | Phase 1 / Phase 2 | 20 | University Hospital TuebingenOTHER | 1 | Feb 5, 2026 | clinicaltrials |
| NCT05460533 | A Second Infusion (Early Reinfusion) of Tisagenlecleucel in Children and Young Adults With B-Cell Acute Lymphoblastic Leukemia(B-ALL) | active not recruiting | Phase 2 | 30 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | Feb 4, 2026 | clinicaltrials |
| NCT02990572 | Amish/Mennonite Research Contact Registry | recruiting | — | 1,000 | University of PittsburghOTHER | 1 | Jan 29, 2026 | clinicaltrials |
| NCT05016947 | Venetoclax Plus Inotuzumab for B-ALL | active not recruiting | Phase 1 | 23 | Dana-Farber Cancer InstituteOTHER | 1 | Jan 29, 2026 | clinicaltrials |
| NCT01199562 | Infection Prophylaxis and Management in Treating Cytomegalovirus (CMV) Infection in Patients With Hematologic Malignancies Previously Treated With Donor Stem Cell Transplant | active not recruiting | — | 153 | City of Hope Medical CenterOTHER | 1 | Jan 28, 2026 | clinicaltrials |
| NCT07371533 | Clinical Study of Recombinant Anti-CD19m-CD3 Antibody Injection (A-319)(A-319) | not yet recruiting | N/A | 18 | Shanxi Bethune HospitalOTHER | 0 | Jan 28, 2026 | clinicaltrials |
| NCT07366801 | Co-infusion of Treg-enriched Donor Lymphocytes With CD3-depleted Hematopoietic Stem Cell Graft to Prevent Graft-versus Host Disease After Allogeneic Hematopoietic Stem Cell Transplantation Among Children With Hematologic Malignancies | recruiting | Phase 2 / Phase 3 | 64 | Federal Research Institute of Pediatric Hematology, Oncology and ImmunologyOTHER | 1 | Jan 26, 2026 | clinicaltrials |
| NCT03642626 | MT2017-45: CAR-T Cell Therapy for Heme Malignancies | active not recruiting | Phase 2 | 150 | Masonic Cancer Center, University of MinnesotaOTHER | 1 | Jan 23, 2026 | clinicaltrials |
| NCT06326463 | CAR T-cell Therapy Directed to CD70 for Pediatric Patients With Hematological Malignancies | recruiting | Phase 1 | 18 | St. Jude Children's Research HospitalOTHER | 1 | Jan 23, 2026 | clinicaltrials |
| NCT07361029 | CD19 Chimeric Antigen Receptor (CAR) T Cells in Adults With Relapsed/Refractory CD19 Positive Acute Lymphoblastic Leukemia(CD19 CART CELL) | recruiting | Phase 1 | 24 | King Faisal Specialist Hospital & Research CenterOTHER | 1 | Jan 22, 2026 | clinicaltrials |
| NCT05512169 | Pharmacogenomic Association Study in Indian Children With Acute Lymphoblastic Leukemia(MPGx-INDALL) | recruiting | — | 556 | University of Geneva, SwitzerlandOTHER | 1 | Jan 15, 2026 | clinicaltrials |
| NCT04872478 | Pharmacokinetic and Safety Study of MRX-2843 in Adolescents and Adults With Relapsed/Refractory AML, ALL, or MPAL | recruiting | Phase 1 | 50 | Meryx, Inc.INDUSTRY | 1 | Jan 8, 2026 | clinicaltrials |
| NCT04928599 | Financial Distress During Treatment for Pediatric Acute Lymphoblastic Leukemia in the United States | active not recruiting | — | 100 | Children's Oncology GroupNETWORK | 2 | Jan 8, 2026 | clinicaltrials |
| NCT07320534 | Levofloxacin Prophylaxis to Prevent First Febrile Neutropenia in Pediatric ALL During Induction Phase | not yet recruiting | Phase 4 | 124 | Gadjah Mada UniversityOTHER | 1 | Jan 8, 2026 | clinicaltrials |
| NCT07326930 | Tracjectories and Predictors of Chemotherapy Induced Peripheral Neuropathy in Children With Acute Lymphoblastic Leukemia | recruiting | — | 173 | The Hong Kong Polytechnic UniversityOTHER | 1 | Jan 8, 2026 | clinicaltrials |
| NCT07327138 | Children's Laughter and Fun Yoga as Adjunctive Pain Relief Following Chemotherapy.(CLAP) | recruiting | N/A | 60 | Bahaa Bou DarghamOTHER | 1 | Jan 8, 2026 | clinicaltrials |
| NCT03481881 | Pharmacokinetics of Drugs Administered to Children | recruiting | — | 200 | Duke UniversityOTHER | 1 | Jan 7, 2026 | clinicaltrials |
| NCT03674411 | Trial Evaluating MGTA-456 in Patients With High-Risk Malignancy | active not recruiting | Phase 2 | 22 | Masonic Cancer Center, University of MinnesotaOTHER | 1 | Jan 6, 2026 | clinicaltrials |
| NCT06514768 | JY231 (JY231) Injection for the Treatment of B-cell Acute Lymphoblastic Leukemia (B-ALL) | recruiting | Early Phase 1 | 20 | 920th Hospital of Joint Logistics Support Force of People's Liberation Army of ChinaOTHER | 1 | Jan 6, 2026 | clinicaltrials |
Data updated 23 days agoSource updated Mar 9, 2026source: clinicaltrials