Hematologic Malignancy
Acute Leukemia
CI-CAN-00000399Explore in graph →
Hematologic1,259 active trials30 approved drugs323 evidence items
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Hematologic Malignancy
CI-CAN-00000399Explore in graph →
Clinical trials
4,655 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (720)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT04488237 | Vitamin D and Methotrexate Adverse Effects | unknown | — | 50 | Assiut UniversityOTHER | 0 | Jul 27, 2020 | clinicaltrials |
| NCT04288739 | Immunophenotyping and Xist Gene in AML(Xist) | unknown | — | 65 | Assiut UniversityOTHER | 1 | Jul 9, 2020 | clinicaltrials |
| NCT04446130 |
| Study of Decitabine Combined With HAAG Regimen in Newly Diagnosed ETP-ALL/LBL, T/M-MPAL and ALL/LBL With Myeloid or Stem Cell Markers Patients |
| unknown |
| Phase 3 |
| 100 |
| The First Affiliated Hospital of Soochow UniversityOTHER |
| 1 |
| Jun 24, 2020 |
| clinicaltrials |
| NCT04437420 | Preclinical Project on the Traitment of Acute Lymphoblastique Leukemia With NVP-BEP800, an Inhibitor of the Heat Shock Protein HSP90(HSP-HEMATO) | unknown | — | 44 | Centre Hospitalier Universitaire DijonOTHER | 1 | Jun 23, 2020 | clinicaltrials |
| NCT04272957 | A Study of HMPL-306 in Patients With IDH1 and/or IDH2 Mutation of Relapsed/Refractory Myeloid Leukemia/Neoplasms | unknown | Phase 1 | 75 | Hutchison Medipharma LimitedINDUSTRY | 1 | Jun 16, 2020 | clinicaltrials |
| NCT04424095 | Venous Disease in Pediatric Population(VEDIPEDI) | unknown | — | 100 | University of CatanzaroOTHER | 1 | Jun 9, 2020 | clinicaltrials |
| NCT04129099 | A Study of GC022F CAR-T Cell Immunotherapy for Relapsed or Refractory B- ALL | unknown | Early Phase 1 | 18 | Hebei Yanda Ludaopei HospitalOTHER | 1 | May 28, 2020 | clinicaltrials |
| NCT04392310 | Outcomes of Acute Myeloid Leukemia Patients | unknown | — | 50 | Assiut UniversityOTHER | 0 | May 18, 2020 | clinicaltrials |
| NCT04369287 | Prevalence and Clinical Effect of IDH1/2 Mutations in Patients With Acute Myeloid Leukemia(Euro_IDH_AML) | unknown | — | 654 | Istituto Clinico HumanitasOTHER | 1 | May 13, 2020 | clinicaltrials |
| NCT04364451 | Correlation of Polymorphisms of Lipoprotein Lipase (LpL) and Apolipoprotein E (Apo E) With Lipid Profile of Children With Acute Lymphoblastic Eukaemia During Therapy With L - Asparaginase. | unknown | — | 90 | Aristotle University Of ThessalonikiOTHER | 1 | Apr 28, 2020 | clinicaltrials |
| NCT04351022 | CD38-targeted Chimeric Antigen Receptor T Cell (CART) in Relapesd or Refractory Acute Myeloid Leukemia | unknown | Phase 1 / Phase 2 | 20 | The First Affiliated Hospital of Soochow UniversityOTHER | 1 | Apr 24, 2020 | clinicaltrials |
| NCT03547258 | Italian Non-Interventional Study of FLT3 Mutated AML Patients(FLAM) | unknown | — | 800 | Istituto Romagnolo per lo Studio dei Tumori Dino Amadori IRST S.r.l. IRCCSOTHER | 1 | Apr 21, 2020 | clinicaltrials |
| NCT04070807 | Italian Observational Study of Patients With Acute Myeloid Leukemia Treated With Small Molecule Inhibiting BCL-2(AVALON) | unknown | — | 70 | Istituto Romagnolo per lo Studio dei Tumori Dino Amadori IRST S.r.l. IRCCSOTHER | 1 | Apr 21, 2020 | clinicaltrials |
| NCT01695512 | Diagnostic Study of Combined Biomnarker Testing in Bronchoalveolar Lavage Samples of Immunocompromised Patients | unknown | — | 200 | Heidelberg UniversityOTHER | 1 | Apr 20, 2020 | clinicaltrials |
| NCT04353479 | Combined PD1 Inhibitor and Decitabine in Elderly Patients With Relapse and Refractory Acute Myeloid Leukemia | unknown | Phase 2 | 29 | Shanghai Jiao Tong University School of MedicineOTHER | 0 | Apr 20, 2020 | clinicaltrials |
| NCT02638428 | Genomics-Based Target Therapy for Children With Relapsed or Refractory Malignancy | unknown | Phase 2 | 90 | Samsung Medical CenterOTHER | 1 | Mar 19, 2020 | clinicaltrials |
| NCT04311060 | Genetic and Molecular Characteristics of Mexican Adults With Acute Myeloid Leukemia: a Prospective Multicentric Study. | unknown | — | 100 | Mexican Agrupation for Hematology StudyOTHER | 1 | Mar 17, 2020 | clinicaltrials |
| NCT03297528 | Chemotherapy and DLI for Prevention of Second Relapse in Patients With Relapsed Acute Leukemia After Allotransplant | unknown | Phase 2 | 40 | Peking University People's HospitalOTHER | 1 | Mar 10, 2020 | clinicaltrials |
| NCT02667093 | Samples From Leukemia Patients and Their Donors to Identify Specific Antigens | unknown | — | 50 | PersImmune, IncINDUSTRY | 1 | Mar 4, 2020 | clinicaltrials |
| NCT03755856 | Long-term Outcomes for Acute Myeloid Leukemia Patients(1621-QLG-LG) | unknown | — | 343 | Gruppo Italiano Malattie EMatologiche dell'AdultoOTHER | 8 | Mar 4, 2020 | clinicaltrials |
| NCT04226989 | A Study of CT-RD06 Cell Injection in Patients With Relapsed or Refractory CD19+ B-cell Hematological Malignancy | unknown | Early Phase 1 | 72 | He HuangOTHER | 1 | Feb 21, 2020 | clinicaltrials |
| NCT01619761 | NK Cells in Cord Blood Transplantation | unknown | Phase 1 | 13 | M.D. Anderson Cancer CenterOTHER | 1 | Feb 11, 2020 | clinicaltrials |
| NCT04264039 | Anti-CD19 U-CAR-T Cell Therapy for B Cell Hematologic Malignancies | unknown | Early Phase 1 | 30 | Xinqiao Hospital of ChongqingOTHER | 1 | Feb 11, 2020 | clinicaltrials |
| NCT01953770 | Childhood Acute Lymphoblastic Leukemia Treatment Protocol Moscow-Berlin 2008(ALL-MB 2008) | unknown | N/A | 3,000 | Federal Research Institute of Pediatric Hematology, Oncology and ImmunologyOTHER | 3 | Feb 5, 2020 | clinicaltrials |
| NCT02059720 | Haplo-SCT vs ASCT With or Without Decitabine in AML CR1 | unknown | Phase 3 | 212 | The First Affiliated Hospital of Soochow UniversityOTHER | 1 | Feb 5, 2020 | clinicaltrials |
| NCT02156297 | Sorafenib to Treat FLT3-ITD AML | unknown | — | 100 | The First Affiliated Hospital of Soochow UniversityOTHER | 1 | Feb 5, 2020 | clinicaltrials |
| NCT03390387 | Childhood Acute Lymphoblastic Leukemia Treatment Protocol Moscow-Berlin 2015 (ALL-MB 2015)(ALL-MB 2015) | unknown | N/A | 4,000 | Federal Research Institute of Pediatric Hematology, Oncology and ImmunologyOTHER | 5 | Feb 5, 2020 | clinicaltrials |
| NCT04206943 | Study of CD19 Specific Chimeric Antigen Receptor Positive T Cells (CAR-T) in ALL and NHL(ISIKOK-19) | unknown | Phase 1 / Phase 2 | 24 | Acibadem UniversityOTHER | 1 | Jan 27, 2020 | clinicaltrials |
| NCT02272478 | Trial to Test the Effects of Adding 1 of 2 New Treatment Agents to Commonly Used Chemotherapy Combinations(AML18) | unknown | Phase 2 / Phase 3 | 1,600 | Cardiff UniversityOTHER | 2 | Jan 23, 2020 | clinicaltrials |
| NCT02605460 | Chemo Sensitization Before Hematopoietic Stem Cell Transplantation in Patients With Acute Leukemia in Complete Remission | unknown | Phase 2 | 20 | Instituto Nacional de Ciencias Medicas y Nutricion Salvador ZubiranOTHER | 1 | Jan 14, 2020 | clinicaltrials |
| NCT03339700 | Addition of Gemcitabine to Pre Allo-HSCT Conditioning for Acute Lymphoblastic Leukemia | unknown | Phase 2 | 15 | Instituto Nacional de Ciencias Medicas y Nutricion Salvador ZubiranOTHER | 1 | Jan 14, 2020 | clinicaltrials |
| NCT04154709 | CTA101 UCAR-T Cell Injection for Treatment of Relapsed or Refractory CD19+ B-cell Acute Lymphoblastic Leukemia | unknown | Phase 1 | 15 | Kai Lin Xu; Jun Nian ZhengOTHER | 1 | Jan 14, 2020 | clinicaltrials |
| NCT04228393 | The Individualized Treatment of 6-mercaptopurine in Children With Acute Lymphoblastic Leukemia in China | unknown | Phase 2 / Phase 3 | 82 | Wei ZhaoOTHER | 1 | Jan 14, 2020 | clinicaltrials |
| NCT03977103 | Irradiation-based Myeloablative Conditioning Followed by Treg/Tcon Immunotherapy in HSCT | unknown | Phase 2 | 80 | University Of PerugiaOTHER | 1 | Jan 13, 2020 | clinicaltrials |
| NCT04221620 | Effectiveness of EEG Neurofeedback in Pediatric Occupational Therapy to Improve Executive Functioning | unknown | N/A | 30 | Northern Arizona UniversityOTHER | 1 | Jan 9, 2020 | clinicaltrials |
| NCT04215822 | PHF19 Gene Expression and EZH2 Gene Deletion in Acute Myeloid Leukemia | unknown | — | 80 | Assiut UniversityOTHER | 0 | Jan 3, 2020 | clinicaltrials |
| NCT04216771 | Comparing the Consolidation Regimens of IDA With Intermediate-dose Cytarabine Versus Intermediate-dose Cytarabine Alone for Elderly AML Patients | unknown | Phase 2 / Phase 3 | 320 | Fujian Medical UniversityOTHER | 1 | Jan 3, 2020 | clinicaltrials |
| NCT04196205 | Anti-CD19 CAR-T Cells for Relapsed or Refractory Acute Lymphoblastic Leukemia and Lymphomas | unknown | Phase 1 / Phase 2 | 20 | The First Affiliated Hospital of Nanchang UniversityOTHER | 1 | Dec 12, 2019 | clinicaltrials |
| NCT03638206 | Autologous CAR-T/TCR-T Cell Immunotherapy for Malignancies | unknown | Phase 1 / Phase 2 | 73 | Shenzhen BinDeBio Ltd.INDUSTRY | 1 | Dec 11, 2019 | clinicaltrials |
| NCT04191941 | Treatment of Hematological Malignancy With Novel CAR-T Cells. | unknown | Early Phase 1 | 9 | Timmune Biotech Inc.INDUSTRY | 1 | Dec 10, 2019 | clinicaltrials |
| NCT04184414 | The Clinical Application of Chimeric Antigen Receptor T Cells in the Treatment of CD19 Positive Recurrent Refractory B Cell-derived Hematological Malignancies | unknown | Early Phase 1 | 10 | PersonGen BioTherapeutics (Suzhou) Co., Ltd.INDUSTRY | 1 | Dec 3, 2019 | clinicaltrials |
| NCT04175587 | Randomized,International Multi-center Clinical Trial of RIF Plus RA for Non-high-risk APL(RIF) | unknown | Phase 3 | 109 | Peking University People's HospitalOTHER | 0 | Nov 29, 2019 | clinicaltrials |
| NCT03110640 | Anti-CD19 CAR T Infusion Combined With Allogeneic Stem Cell Transplantation for B-cell Leukemia/Lymphoma | unknown | Phase 1 | 20 | First Affiliated Hospital of Wenzhou Medical UniversityOTHER | 1 | Nov 27, 2019 | clinicaltrials |
| NCT03260101 | Non-interventional, Long-term Follow-up of Subjects Who Completed ApoGraft-01 Study | unknown | — | 12 | Cellect BiotechnologyINDUSTRY | 1 | Nov 26, 2019 | clinicaltrials |
| NCT04168138 | D-CTAG in the Treatment of Newly Diagnosed Acute Myeloid Leukemia in Elderly Patients | unknown | N/A | 20 | Huihan WangOTHER | 1 | Nov 19, 2019 | clinicaltrials |
| NCT04166838 | The Clinical Study of CD19 UCAR-T Cells in Patients With B-cell Acute Lymphoblastic Leukemia (B-ALL) | unknown | Early Phase 1 | 20 | Shanghai Longyao Biotechnology Inc., Ltd.OTHER | 1 | Nov 18, 2019 | clinicaltrials |
| NCT04156256 | CD123-CD33 cCAR in Patients With Relapsed and/or Refractory, High Risk Hematologic Malignancies | unknown | Early Phase 1 | 20 | iCell Gene TherapeuticsINDUSTRY | 1 | Nov 12, 2019 | clinicaltrials |
| NCT04158011 | A Retrospective Study of Patients With Leukemia Relapse in the CNS Treated With CAR T Cells | unknown | — | 80 | Sheba Medical CenterOTHER_GOV | 1 | Nov 8, 2019 | clinicaltrials |
| NCT02619630 | Multicenter Study of Risk-adapted Treatment for T-lineage ALL of Young Adults (18-59 Years Old)(GRAALL-2014/T) | unknown | Phase 2 | 275 | Assistance Publique - Hôpitaux de ParisOTHER | 1 | Oct 21, 2019 | clinicaltrials |
| NCT02809092 | Interleukin-21 (IL-21)- Expanded Natural Killer Cells for Induction of Acute Myeloid Leukemia | unknown | Phase 1 / Phase 2 | 30 | Hospital de Clinicas de Porto AlegreOTHER | 1 | Oct 15, 2019 | clinicaltrials |
Data updated 23 days agoSource updated Jul 27, 2020source: clinicaltrials