Clinical trial · Observational
Venous Disease in Pediatric Population
Investigation of Chronic Venous Disease in Pediatric Population
NCT04424095CI-TRIAL-00045443VEDIPEDIunknownClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Chronic venous disease (CVD) is widespread in adult subjects of western countries and is responsible of important morbidity and healthcare costs. CVD has never been extensively studied in pediatric population where the early pathophysiological alterations may occur undetected. The aim of this study is to assess the prevalence of CVD searching also for the early clinical and instrumental signs of this disease.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Chronic Venous Insufficiency | — | UNRESOLVED | — |
| Pediatric ALL | Childhood Acute Lymphoblastic Leukemia | ALIAS | 0.90 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Echo Duplex of lower limbs | Diagnostic Test | — | UNRESOLVED |
| In-office vascular visit | Diagnostic Test | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- label
- Pediatric patients
- description
- Recruited pediatric patients will undergo an in-office vascular visit and an echo duplex scan of lower limbs, in order to detect any symptoms or signs related to chronic venous disease.
- interventionNames
- Diagnostic Test: In-office vascular visit
- Diagnostic Test: Echo Duplex of lower limbs
Primary outcomes (2)
- measure
- Prevalence of Chronic Venous Disease
- timeFrame
- at 9 month
- description
- The Prevalence of Chronic Venous Disease in the population study will be assessed.
- measure
- Echo duplex evaluation
- timeFrame
- at 10 month
- description
- The correlation between veins diameter and the presence of reflux will be evaluated in pediatric population
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 9 Years
- Maximum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Pediatric Patients Exclusion Criteria: * Patients with mental retardation * Patients with Marfan syndrome * Patients with an inability to stand or collaborate for the clinical tests.
References
Publications (3)
- BACKGROUNDRobertson L, Evans C, Fowkes FG. Epidemiology of chronic venous disease. Phlebology. 2008;23(3):103-11. doi: 10.1258/phleb.2007.007061. PMID 18467617
- BACKGROUNDBeebe-Dimmer JL, Pfeifer JR, Engle JS, Schottenfeld D. The epidemiology of chronic venous insufficiency and varicose veins. Ann Epidemiol. 2005 Mar;15(3):175-84. doi: 10.1016/j.annepidem.2004.05.015. PMID 15723761
- BACKGROUNDGriffiths L, Vasudevan V, Myers A, Morganstern BA, Palmer LS. The role of inheritance in the development of adolescent varicoceles. Transl Androl Urol. 2018 Dec;7(6):920-925. doi: 10.21037/tau.2018.09.02. PMID 30505728