Variant · Fusion
NUTM1 Fusion
CI-VAR-00001418Explore in graph →CIViC 4973
Curated evidence
Evidence by cancer (6 items)
Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.
- Source
- CIViC — Clinical Interpretation of Variants in Cancer
- Dataset
- CIViC evidence items
- Version
- civic-2026-09-08
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- expert curation
- License
- CC0 1.0
- PMID
- 18391746
- Run
- ING-CIVIC-20260908-000001
| Molecular profile | Therapy | Type | Level | Direction · significance | Rating (1–5) | Status | Evidence | Source |
|---|---|---|---|---|---|---|---|---|
| NUT Carcinoma6 | ||||||||
| BRD4::NUTM1 Fusion | (diagnostic) | Diagnostic | B | Supports Positive | 3 | accepted | EID70195 of 28 cases of undifferentiated carcinomas of the upper aerodigestive tract (UCUAT) not associated with EBV infection were found to have NUTM1 rearrangements suggesting NUT midline carcinoma may be… (full text at CIViC) PMID 18391746 · Stelow et al., 2008 · Open in CIViC | civic |
| BRD4::NUTM1 Fusion | (diagnostic) | Diagnostic | B | Supports Positive | 4 | accepted | EID12049In this 2017 study, the authors sought to characterize NUT carcinomas. They included a cohort of 12 aggressive malignant tumors with rearrangement of the NUTM1 gene, assessed by RT-PCR, FISH, positive… (full text at CIViC) PMID 28643357 · Lemelle et al., 2017 · Open in CIViC | civic |
| BRD4::NUTM1 Fusion | ||||||||
ClinVar
Clinical significance (0)
ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.
Data not yet available