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Clinical trials
Studies registered on ClinicalTrials.gov whose conditions were reconciled to the cancer taxonomy. Status and phase are as posted by the registrant.
1,225 studies match
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT04072263 | Adoptive T Cell Therapy in Patients With Recurrent Ovarian Cancer(OVACURE) | unknown | Phase 1 / Phase 2 | 12 | Leiden University Medical CenterOTHER | 1 | Apr 1, 2021 | clinicaltrials |
| NCT01835236 | Trastuzumab & Pertuzumab Followed by T-DM1 in MBC | completed | Phase 2 | 208 | Swiss Cancer InstituteOTHER | 4 | Mar 30, 2021 | clinicaltrials |
| NCT04495010 | Neoadjuvant Nivolumab+Ipilimumab Followed by Adjuvant Nivolumab or Neoadjuvant Nivolumab+Ipilimumab Followed by Adjuvant Observation Compared With Adjuvant Nivolumab in Treatment-Naive High-risk Melanoma Participants(CheckMate 7UA) | withdrawn | Phase 2 | 0 | Bristol-Myers SquibbINDUSTRY | 16 | Mar 19, 2021 | clinicaltrials |
| NCT02054442 | A Study of the Combination of Cetuximab and Methotrexate in Recurrent or Metastatic Cancer of the Head and Neck(COMMENCE) | unknown | Phase 1 / Phase 2 | 52 | Radboud University Medical CenterOTHER | 1 | Mar 12, 2021 | clinicaltrials |
| NCT03729297 | Cabozantinib in Advanced Salivary Gland Cancer Patients(Cabo ASAP) | terminated | Phase 2 | 25 | Radboud University Medical CenterOTHER | 1 | Mar 12, 2021 | clinicaltrials |
| NCT02372006 | Trial of Afatinib in Pediatric Tumours | completed | Phase 1 / Phase 2 | 56 | Boehringer IngelheimINDUSTRY | 12 | Mar 4, 2021 | clinicaltrials |
| NCT03863301 | MRI-guided Single Dose Preoperative Radiotherapy in Low-risk Breast Cancer(ABLATIVE-2) | withdrawn | Phase 2 | 0 | UMC UtrechtOTHER | 1 | Feb 26, 2021 | clinicaltrials |
| NCT01927341 | Phase Ib/II Study of Efficacy and Safety of MEK162 and Panitumumab, in Adult mCRC Patients With Mutant or Wild-type RAS Tumors | completed | Phase 1 / Phase 2 | 53 | PfizerINDUSTRY | 7 | Feb 18, 2021 | clinicaltrials |
| NCT04761172 | NIR Fluorescence Imaging With ICG for the Intraoperative Identification of Gastrointestinal Stromal Cell Tumours | unknown | Phase 2 / Phase 3 | 10 | Leiden University Medical CenterOTHER | 1 | Feb 18, 2021 | clinicaltrials |
| NCT00642941 | A Study of R1507 in Participants With Recurrent or Refractory Sarcoma | terminated | Phase 2 | 317 | Hoffmann-La RocheINDUSTRY | 11 | Feb 3, 2021 | clinicaltrials |
| NCT04737213 | SGM-101 in Colorectal Lung Metastases(SGM-CLM) | unknown | Phase 2 | 10 | Leiden University Medical CenterOTHER | 1 | Feb 3, 2021 | clinicaltrials |
| NCT01207440 | Ponatinib for Chronic Myeloid Leukemia (CML) Evaluation and Ph+ Acute Lymphoblastic Leukemia (ALL)(PACE) | completed | Phase 2 | 449 | Ariad PharmaceuticalsINDUSTRY | 11 | Feb 2, 2021 | clinicaltrials |
| NCT01359397 | Docetaxel, Oxaliplatin, Capecitabine, Bevacizumab and Trastuzumab in Patients With Locally Advanced or Metastatic Gastric Cancer(B-DOCT) | unknown | Phase 2 | — | The Netherlands Cancer InstituteOTHER | 1 | Jan 27, 2021 | clinicaltrials |
| NCT02470533 | Transarterial Chemoembolization Versus Stereotactic Body Radiation Therapy for Hepatocellular Carcinoma(TRENDY) | terminated | Phase 2 | 100 | Erasmus Medical CenterOTHER | 3 | Jan 27, 2021 | clinicaltrials |
| NCT00448266 | Intensified IAA With PBPC Support in Breast Tumors With Evidence of a HRD | terminated | Phase 2 / Phase 3 | 12 | The Netherlands Cancer InstituteOTHER | 1 | Jan 22, 2021 | clinicaltrials |
| NCT00738777 | Pre-operative Hormonal Treatment for Hormone Receptor Positive Breast Cancer | suspended | Phase 2 | 250 | The Netherlands Cancer InstituteOTHER | 1 | Jan 22, 2021 | clinicaltrials |
| NCT03048474 | Ipilimumab and Nivolumab in the Treatment of Malignant Pleural Mesothelioma(INITIATE) | completed | Phase 2 | 36 | The Netherlands Cancer InstituteOTHER | 1 | Jan 20, 2021 | clinicaltrials |
| NCT03986294 | Second Line Treatment With Nal-IRI and S1 in Pancreatic Cancer(NAPAN) | unknown | Phase 2 | 122 | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)OTHER | 1 | Jan 15, 2021 | clinicaltrials |
| NCT03620149 | Reduced Dose-density of Denosumab for Unresectable GCTB(REDUCE) | terminated | Phase 2 | 2 | European Organisation for Research and Treatment of Cancer - EORTCNETWORK | 4 | Jan 6, 2021 | clinicaltrials |
| NCT02853162 | Ablative tReatment of Inoperable REnal Cell Carcinoma Using STereotactic Body Radiotherapy (ARREST-study)(ARREST) | terminated | Phase 2 | 30 | UMC UtrechtOTHER | 1 | Jan 5, 2021 | clinicaltrials |
| NCT01602315 | A Phase Ib/II Study of BYL719 and Cetuximab in Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma | terminated | Phase 1 / Phase 2 | 179 | Novartis PharmaceuticalsINDUSTRY | 9 | Dec 29, 2020 | clinicaltrials |
| NCT03742713 | Efficacy Study of CPC634 (CriPec® Docetaxel) in Platinum Resistant Ovarian Cancer(CINOVA) | completed | Phase 2 | 25 | Cristal TherapeuticsINDUSTRY | 3 | Dec 28, 2020 | clinicaltrials |
| NCT01058434 | Safety and Efficacy of TKI258 in Relapsed or Refractory Multiple Myeloma Patients, Who Are With or Without t(4;14) Chromosomal Translocation | completed | Phase 2 | 43 | Novartis PharmaceuticalsINDUSTRY | 7 | Dec 19, 2020 | clinicaltrials |
| NCT00526045 | Phase I-II Study to Determine the Maximum Tolerated Dose (MTD) of AUY922 in Advanced Solid Malignancies, and Efficacy in HER2+ or ER+ Locally Advanced or Metastatic Breast Cancer Patients | completed | Phase 1 / Phase 2 | 117 | Novartis PharmaceuticalsINDUSTRY | 4 | Dec 17, 2020 | clinicaltrials |
| NCT01084330 | Phase II Trial of AUY922 vs. Comparators in Advanced Gastric Cancer | completed | Phase 2 | 68 | Novartis PharmaceuticalsINDUSTRY | 14 | Dec 10, 2020 | clinicaltrials |
| NCT03356054 | Phase I-II Study in CD30 Positive Diffuse Large B-cell Lymphoma Patients Refractory to First Line Chemotherapy or in First Relapse(HOVON 136 NHL) | recruiting | Phase 1 / Phase 2 | 37 | Stichting Hemato-Oncologie voor Volwassenen NederlandOTHER | 1 | Dec 10, 2020 | clinicaltrials |
| NCT01249820 | Pharmacokinetics of Anidulafungin (Ecalta ®) Intravenous Given to Patients at High Risk for Developing Invasive Fungal Disease(ANIDULAPK) | completed | Phase 2 | 26 | Radboud University Medical CenterOTHER | 1 | Dec 8, 2020 | clinicaltrials |
| NCT01781572 | A Phase Ib/II Study of LEE011 in Combination With MEK162 in Patients With NRAS Mutant Melanoma | completed | Phase 1 / Phase 2 | 102 | PfizerINDUSTRY | 5 | Dec 7, 2020 | clinicaltrials |
| NCT04642924 | SGM-101 in Locally Advanced and Recurrent Rectal Cancer(SGM-LARRC) | unknown | Phase 2 / Phase 3 | 203 | Leiden University Medical CenterOTHER | 1 | Nov 24, 2020 | clinicaltrials |
| NCT03909724 | Pulsatile High-dose Sunitinib Versus TAS-102 in Patients With Metastatic Colorectal Carcinoma (mCRC)(SUNRISE-CRC) | unknown | Phase 2 / Phase 3 | 60 | Amsterdam UMC, location VUmcOTHER | 1 | Nov 13, 2020 | clinicaltrials |
| NCT02610140 | Phase II Anetumab Ravtansine as 2nd Line Treatment for Malignant Pleural Mesothelioma (MPM) | completed | Phase 2 | 248 | BayerINDUSTRY | 14 | Nov 4, 2020 | clinicaltrials |
| NCT03877601 | Detection of Early Esophageal Cancer by NIR-FME.(ESCEND) | unknown | Phase 2 | 60 | University Medical Center GroningenOTHER | 1 | Nov 4, 2020 | clinicaltrials |
| NCT02300987 | A Randomized, Blinded, Placebo-controlled, Phase II Trial of LEE011 in Patients With Relapsed, Refractory, Incurable Teratoma With Recent Progression | completed | Phase 2 | 10 | Novartis PharmaceuticalsINDUSTRY | 4 | Oct 26, 2020 | clinicaltrials |
| NCT01897714 | Safety and Efficacy of Melflufen and Dexamethasone in Relapsed and/or Relapsed-Refractory Multiple Myeloma Patients | terminated | Phase 1 / Phase 2 | 75 | Oncopeptides ABINDUSTRY | 5 | Oct 23, 2020 | clinicaltrials |
| NCT03287804 | APRIL CAR T Cells (AUTO2) Targeting BCMA and TACI for the Treatment of Multiple Myeloma(APRIL) | terminated | Phase 1 / Phase 2 | 12 | Autolus LimitedINDUSTRY | 2 | Oct 23, 2020 | clinicaltrials |
| NCT01816230 | Transplantation of NiCord®, Umbilical Cord Blood-derived Ex Vivo Expanded Cells, in Patients With HM | completed | Phase 1 / Phase 2 | 36 | Gamida Cell ltdINDUSTRY | 5 | Oct 22, 2020 | clinicaltrials |
| NCT01896856 | Phase I/II Study of SGI-110 With Irinotecan Versus Regorafenib or TAS-102 in Metastatic Colorectal Cancer | completed | Phase 1 / Phase 2 | 118 | Sidney Kimmel Comprehensive Cancer Center at Johns HopkinsOTHER | 2 | Oct 6, 2020 | clinicaltrials |
| NCT00981799 | Trial of Nelarabine, Etoposide and Cyclophosphamide in Relapsed T-cell ALL and T-cell LL | terminated | Phase 1 / Phase 2 | 23 | Therapeutic Advances in Childhood Leukemia ConsortiumOTHER | 7 | Oct 1, 2020 | clinicaltrials |
| NCT00835471 | 2nd Line Erlotinib Treatment With (Out) Chemotherapy of Advanced Non Small Cell Lung Cancer (NSCLC)(NVALT10) | completed | Phase 2 | 195 | Dutch Society of Physicians for Pulmonology and TuberculosisOTHER | 1 | Sep 29, 2020 | clinicaltrials |
| NCT01171170 | Paclitaxel-Carboplatin-Bevacizumab +/- Nitroglycerin in Metastatic Non-Squamous-Non-Small Cell Lung Cancer(NVALT12) | completed | Phase 2 | 223 | Dutch Society of Physicians for Pulmonology and TuberculosisOTHER | 1 | Sep 28, 2020 | clinicaltrials |
| NCT01915303 | Study of the Efficacy and Safety of Pasireotide s.c. +/- Cabergoline in Patients With Cushing's Disease | terminated | Phase 2 | 68 | Novartis PharmaceuticalsINDUSTRY | 16 | Sep 18, 2020 | clinicaltrials |
| NCT04552093 | Hepatic Arterial Infusion Pump Chemotherapy Combined With Systemic Chemotherapy (PUMP-IT)(PUMP-IT) | unknown | Phase 2 / Phase 3 | 31 | The Netherlands Cancer InstituteOTHER | 1 | Sep 17, 2020 | clinicaltrials |
| NCT01801358 | A Phase Ib/II Study of AEB071 and MEK162 in Adult Patients With Metastatic Uveal Melanoma | terminated | Phase 1 / Phase 2 | 38 | Array Biopharma, now a wholly owned subsidiary of PfizerINDUSTRY | 6 | Sep 16, 2020 | clinicaltrials |
| NCT02492568 | Pembrolizumab After SBRT Versus Pembrolizumab Alone in Advanced NSCLC(PEMBRO-RT) | completed | Phase 2 | 92 | The Netherlands Cancer InstituteOTHER | 1 | Aug 17, 2020 | clinicaltrials |
| NCT02147990 | Multicenter Study of Rociletinib Administered to Patients With Previously Treated Mutant EGFR Non-small Cell Lung Cancer(NSCLC) | terminated | Phase 2 | 318 | Clovis Oncology, Inc.INDUSTRY | 12 | Aug 12, 2020 | clinicaltrials |
| NCT01390948 | A Study of Bevacizumab (Avastin) in Combination With Temozolomide (TMZ) and Radiotherapy in Paediatric and Adolescent Participants With High-Grade Glioma | completed | Phase 2 | 124 | Hoffmann-La RocheINDUSTRY | 14 | Aug 6, 2020 | clinicaltrials |
| NCT01788982 | Nintedanib(BIBF1120) in Thyroid Cancer | completed | Phase 2 | 100 | European Organisation for Research and Treatment of Cancer - EORTCNETWORK | 9 | Jul 31, 2020 | clinicaltrials |
| NCT00088205 | Oral Enzastaurin in Participants With Relapsed Mantle Cell Lymphoma | completed | Phase 2 | 60 | Eli Lilly and CompanyINDUSTRY | 4 | Jul 1, 2020 | clinicaltrials |
Data updated 24 days agoSource updated unknownsource: clinicaltrials