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Clinical trials · failure tracking
Oncology studies whose overall status is TERMINATED, WITHDRAWN or SUSPENDED on ClinicalTrials.gov, with the stop reason exactly as the registrant posted it. A category is attached only when an explicit keyword rule matches the text; CancerIndex never infers why a study stopped.
212 stopped studies mapped to Soft Tissue Sarcoma and descendants · 92% state a reason
Over the 212 studies matching the cancer, status and year filters (the category filter does not change this chart). Each study is counted once, in the first matching category; greyed bars are studies whose text matched no rule or was empty.
Computedrules ci-stop-reasons-v1 · keyword matching only
A category is assigned when one of its keywords appears in the posted text (case-insensitive, whole words). Rules are tested in this order and the first match wins; every match is kept in the API (reasonMatches).
| NCT | Title | Phase | Status | First posted | Lead sponsor | Why stopped (as posted) | Category |
|---|---|---|---|---|---|---|---|
| NCT02011126 | Imetelstat Sodium in Treating Younger Patients With Relapsed or Refractory Solid Tumors | Phase 2 | withdrawn | Dec 13, 2013 | Children's Oncology Group | IND no longer available. | Other (stated, no rule matched) |
| NCT03111069 | Study of Doxorubicin and Hyperthermic Intraperitoneal Chemotherapy (HIPEC) and… | Phase 1 | withdrawn | Apr 12, 2017 | M.D. Anderson Cancer Center | PI withdrew study | Other (stated, no rule matched) |
| NCT01328067 | Study to Evaluate the Safety and Effectiveness of MRgFUS Compared With Myomectomy for the… | N/A | withdrawn | Apr 4, 2011 | InSightec | not stated | Not stated |
| NCT00686842 | PTC299 in Treating Patients With HIV-Related Kaposi Sarcoma | Phase 1 / Phase 2 | terminated | May 30, 2008 | AIDS Malignancy Consortium | Drug supply unavailable. | Drug supply |
| NCT00089544 | Preoperative Thalidomide With Radiation Therapy For Patients With Low-Grade Primary Soft… | Phase 2 | terminated | Aug 9, 2004 | National Cancer Institute (NCI) | not stated | Not stated |
| NCT01055028 | Paclitaxel + Bevacizumab (Avastin) for the Treatment of Metastatic or Unresectable… | Phase 2 | terminated | Jan 25, 2010 | Stanford University | Poor accrual | Enrollment / accrual |
| NCT02736435 | Treatment of Uterine Fibroids With Magnetic Resonance Guided High Intensity Focused… | Phase 3 | withdrawn | Apr 13, 2016 | Thunder Bay Regional Health Research Institute | Lengthy delays and inadequate support to proceed. | Other (stated, no rule matched) |
| NCT01984892 | Treatment of Solid Tumors With Intratumoral Hiltonol® (Poly-ICLC)(Hiltonol) | Phase 2 | terminated | Nov 15, 2013 | Nina Bhardwaj | PI discretion, low enrollment | Enrollment / accrual |
| NCT02229981 | Early Phase Evaluation of ABC294640 in Patients With Refractory/Relapsed Diffuse Large…(ABC-102) | Phase 1 / Phase 2 | withdrawn | Sep 3, 2014 | RedHill Biopharma Limited | Study was discontinued due to lack of recruitment. | Enrollment / accrual |
| NCT01169350 | 18F-Fluoromisonidazole and Fludeoxyglucose F 18 PET/CT Patients With Soft Tissue Sarcoma | Phase 2 | terminated | Jul 26, 2010 | National Cancer Institute (NCI) | funding source ended earlier than anticipated | Funding |
| NCT02113826 | Pazopanib for Metastatic Alveolar Soft Part Sarcoma | Phase 2 | terminated | Apr 15, 2014 | Seoul National University Hospital | Low accrual rate | Enrollment / accrual |
| NCT03007771 | Magnetic Resonance-guided High-Intensity Focused Ultrasound (MR-HIFU) Used for Mild… | Phase 1 | withdrawn | Jan 2, 2017 | Washington University School of Medicine | Decision was made to not go forward with the study | Other (stated, no rule matched) |
| NCT00003521 | Antineoplaston Therapy in Treating Patients With Soft Tissue Sarcoma | Phase 2 | terminated | Jan 27, 2003 | Burzynski Research Institute | slow accrual | Enrollment / accrual |
| NCT03149120 | Study of Nivolumab With or Without Pazopanib in Metastatic or Unresectable Soft Tissue… | Phase 2 | withdrawn | May 11, 2017 | NYU Langone Health | No patient enrolled as new similar study will be in system within 3 months | Enrollment / accrual |
| NCT01842789 | Post Market Evaluation of Acessa With TAG(TAG) | N/A | terminated | Apr 30, 2013 | Acessa Health, Inc. | Results to date adequately demonstrated user preference and recovery time. Time to target (Part II)… | Other (stated, no rule matched) |
| NCT01469975 | First in Man Study Investigating the Biodistribution, the Safety and Optimal Recommended…(SYNFRIZZ) | Phase 1 | terminated | Nov 10, 2011 | Centre Leon Berard | Too slow accrual. | Enrollment / accrual |
| NCT02633254 | Targeted Vessel Ablation of Type 3 Uterine Fibroids With Magnetic Resonance Guided High… | N/A | terminated | Dec 17, 2015 | UMC Utrecht | not stated | Not stated |
| NCT01504308 | Sonalleve Fibroid Ablation Pivotal Clinical Trial for MR-HIFU of Uterine Fibroids(SOFIA) | Phase 2 / Phase 3 | terminated | Jan 5, 2012 | Philips Healthcare | It was not possible to enroll patients into the study in a realistic timeframe. | Enrollment / accrual |
| NCT00881595 | Proton Chemoradiotherapy for High-Risk Soft Tissue Sarcomas(SA02) | Phase 2 | withdrawn | Apr 15, 2009 | University of Florida | No patients accrued since study opened | Enrollment / accrual |
| NCT00901836 | Preoperative Proton Radiotherapy for Retroperitoneal Sarcoma(SA03) | N/A | terminated | May 14, 2009 | University of Florida | Study closed due to feasability | Other (stated, no rule matched) |
| NCT01971060 | a Study to Evaluate Adhesion Risk in Fertility Patients' Status Post Laparoscopic…(VLocmyo) | N/A | withdrawn | Oct 28, 2013 | The Advanced Gynecologic Surgery Institute | lack of funding | Funding |
| NCT01061606 | Temsirolimus in Treating Patients With Recurrent or Persistent Cancer of the Uterus | Phase 2 | terminated | Feb 3, 2010 | National Cancer Institute (NCI) | Poor accrual | Enrollment / accrual |
| NCT02367651 | Study of Pazopanib Versus Placebo as Maintenance Therapy for Advanced Soft Tissue Sarcoma | Phase 2 | withdrawn | Feb 20, 2015 | GlaxoSmithKline | Study cancelled: Withdrawn before enrollment of any participants | Enrollment / accrual |
| NCT01555073 | Preemptive Analgesia Following Uterine Artery Embolization | Phase 4 | terminated | Mar 15, 2012 | Northwestern University | Subjects did not meet inclusion criteria | Other (stated, no rule matched) |
| NCT02080416 | Nelfinavir for the Treatment of Gammaherpesvirus-Related Tumors | Early Phase 1 | terminated | Mar 6, 2014 | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | Very slow accrual; terminated to allow resources to be utilized more effectively on other studies.… | Enrollment / accrual |
| NCT02464332 | Safety Study of BLZ-100 in Adult Subjects With Sarcoma Undergoing Surgery | Phase 1 | withdrawn | Jun 8, 2015 | Blaze Bioscience Inc. | Study did not enroll any subjects | Enrollment / accrual |
| NCT01675011 | Embozene Microspheres for Uterine Fibroid Embolization (UFE) | N/A | terminated | Aug 29, 2012 | Boston Scientific Corporation | Inadequate enrollment | Enrollment / accrual |
| NCT02059850 | NY-ESO-1 Specific T Cells After Cyclophosphamide in Treating Patients With Advanced… | Phase 1 | withdrawn | Feb 11, 2014 | Fred Hutchinson Cancer Center | not stated | Not stated |
| NCT02137564 | Gamma Secretase Inhibitor PF-03084014 in Treating Patients With AIDS-Associated Kaposi… | Phase 2 | withdrawn | May 14, 2014 | AIDS Malignancy Consortium | Drug supply unavailable | Drug supply |
| NCT02507076 | Isolated Limb Perfusion With Melphalan in Treating Patients With Stage IIIB-IV Melanoma… | N/A | withdrawn | Jul 23, 2015 | Albert Einstein College of Medicine | no enrollment | Enrollment / accrual |
| NCT00755261 | Phase II Study of Doxorubicin and Avastin® in Sarcoma. | Phase 2 | terminated | Sep 18, 2008 | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | The study has been terminated due to low accrual. | Enrollment / accrual |
| NCT00022542 | BMS-247550 in Treating Patients With Advanced Soft Tissue Sarcoma | Phase 2 | terminated | Feb 27, 2004 | National Cancer Institute (NCI) | not stated | Not stated |
| NCT01226290 | Fibroid Ablation Study(FAST-EU) | N/A | terminated | Oct 22, 2010 | Gynesonics | Investigational device changes; adequate enrollment achieved | Enrollment / accrual |
| NCT00233948 | Nelfinavir Mesylate in Treating Patients With Recurrent, Metastatic, or Unresectable… | Phase 1 / Phase 2 | terminated | Oct 6, 2005 | City of Hope Medical Center | Drug availability issues | Drug supply |
| NCT01539187 | Fibroid Ablation Study - Large Fibroids(FAST-L) | N/A | terminated | Feb 27, 2012 | Gynesonics | Investigational device changes | Other (stated, no rule matched) |
| NCT01998854 | Observational Prospective Study on Patients With Symptomatic Uterine Fibroids Treated… | — | terminated | Dec 2, 2013 | Gynesonics | Investigational device changes | Other (stated, no rule matched) |
| NCT01795430 | Whole-Body Radiation Therapy, Systemic Chemotherapy, and High-Dose Chemotherapy Followed… | N/A | withdrawn | Feb 20, 2013 | City of Hope Medical Center | No participants enrolled. | Enrollment / accrual |
| NCT00615329 | Huntsman Biopsy Study | — | terminated | Feb 14, 2008 | State University of New York - Upstate Medical University | Huntmans Cancer Institute terminated study | Other (stated, no rule matched) |
| NCT01786226 | Mifepristone to Treat Uterine Fibroids | Phase 2 / Phase 3 | terminated | Feb 7, 2013 | Mediterranea Medica S. L. | not stated | Not stated |
| NCT00958893 | An Extension Study Evaluating Safety and Efficacy of Proellex® In Women Who Have… | Phase 2 | terminated | Aug 13, 2009 | Repros Therapeutics Inc. | Repros stopped the study for safety and FDA put the study on hold for safety. | Safety / toxicity |
| NCT00683917 | Pharmacokinetics, Safety and Efficacy Study of Proellex in Pre-menopausal Women With… | Phase 2 | terminated | May 26, 2008 | Repros Therapeutics Inc. | Repros stopped the study for safety and FDA put the study on hold for safety. | Safety / toxicity |
| NCT00702702 | Safety and Efficacy of Proellex in Pre-menopausal Anemic Women With Symptomatic Uterine… | Phase 3 | terminated | Jun 20, 2008 | Repros Therapeutics Inc. | Repros stopped study for safety and FDA put study on hold because of safety. | Safety / toxicity |
| NCT00735553 | Evaluating the Safety and Efficacy of Proellex® (CDB-4124) in Premenopausal Women With… | Phase 3 | terminated | Aug 15, 2008 | Repros Therapeutics Inc. | Repros stopped the study for safety and FDA put the study on hold for safety. | Safety / toxicity |
| NCT00737282 | Multicenter Study Evaluating the Safety of Proellex® in Premenopausal Women With Uterine… | Phase 3 | terminated | Aug 18, 2008 | Repros Therapeutics Inc. | Repros stopped study for safety and FDA put study on hold. | Safety / toxicity |
| NCT00785356 | Safety and Efficacy of Proellex in Pre-Menopausal Anemic Women With Symptomatic Uterine… | Phase 3 | terminated | Nov 5, 2008 | Repros Therapeutics Inc. | Repros stopped the study for safety and FDA put the study on hold for safety. | Safety / toxicity |
| NCT00853567 | Evaluating the Safety and Efficacy of Proellex® in Premenopausal Women With Symptomatic… | Phase 3 | terminated | Mar 2, 2009 | Repros Therapeutics Inc. | Repros stopped the study for safety and FDA put the study on hold for safety. | Safety / toxicity |
| NCT01069120 | Safety of 25 and 50 mg Proellex® in the Treatment of Women With Symptomatic Uterine… | Phase 3 | terminated | Feb 17, 2010 | Repros Therapeutics Inc. | Repros stopped study due to safety and FDA placed study on hold | Safety / toxicity |
| NCT00874302 | Safety and Efficacy of 25 and 50 mg Doses of Proellex® in Treating the Recurrence of… | Phase 3 | withdrawn | Apr 2, 2009 | Repros Therapeutics Inc. | Study terminated for safety and the FDA put the study on hold for safety. | Safety / toxicity |
| NCT00521092 | Sunitinib Malate in Treating East African Patients With Kaposi Sarcoma | Phase 2 | withdrawn | Aug 27, 2007 | National Cancer Institute (NCI) | No participants enrolled. | Enrollment / accrual |
| NCT01491594 | Eltrombopag for the Prevention of Chemotherapy Induced Thrombocytopenia | Phase 1 | terminated | Dec 14, 2011 | Duke University | Unable to accrue subjects to the study. | Enrollment / accrual |
Stop reasons are registrant-reported free text and are displayed verbatim (truncated; hover for the full text). Categories come from explicit keyword rules and are never inferred from the study design, sponsor or outcome; a study that stopped for several reasons is filed under the first rule that matched. A TERMINATED status does not imply a negative result.
Data updated 22 days agoSource updated Aug 7, 2018source: clinicaltrials