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Clinical trials · failure tracking
Oncology studies whose overall status is TERMINATED, WITHDRAWN or SUSPENDED on ClinicalTrials.gov, with the stop reason exactly as the registrant posted it. A category is attached only when an explicit keyword rule matches the text; CancerIndex never infers why a study stopped.
398 stopped studies mapped to Sarcoma and descendants · 90% state a reason
Over the 398 studies matching the cancer, status and year filters (the category filter does not change this chart). Each study is counted once, in the first matching category; greyed bars are studies whose text matched no rule or was empty.
Computedrules ci-stop-reasons-v1 · keyword matching only
A category is assigned when one of its keywords appears in the posted text (case-insensitive, whole words). Rules are tested in this order and the first match wins; every match is kept in the API (reasonMatches).
| NCT | Title | Phase | Status | First posted | Lead sponsor | Why stopped (as posted) | Category |
|---|---|---|---|---|---|---|---|
| NCT00735553 | Evaluating the Safety and Efficacy of Proellex® (CDB-4124) in Premenopausal Women With… | Phase 3 | terminated | Aug 15, 2008 | Repros Therapeutics Inc. | Repros stopped the study for safety and FDA put the study on hold for safety. | Safety / toxicity |
| NCT00737282 | Multicenter Study Evaluating the Safety of Proellex® in Premenopausal Women With Uterine… | Phase 3 | terminated | Aug 18, 2008 | Repros Therapeutics Inc. | Repros stopped study for safety and FDA put study on hold. | Safety / toxicity |
| NCT00785356 | Safety and Efficacy of Proellex in Pre-Menopausal Anemic Women With Symptomatic Uterine… | Phase 3 | terminated | Nov 5, 2008 | Repros Therapeutics Inc. | Repros stopped the study for safety and FDA put the study on hold for safety. | Safety / toxicity |
| NCT00853567 | Evaluating the Safety and Efficacy of Proellex® in Premenopausal Women With Symptomatic… | Phase 3 | terminated | Mar 2, 2009 | Repros Therapeutics Inc. | Repros stopped the study for safety and FDA put the study on hold for safety. | Safety / toxicity |
| NCT01069120 | Safety of 25 and 50 mg Proellex® in the Treatment of Women With Symptomatic Uterine… | Phase 3 | terminated | Feb 17, 2010 | Repros Therapeutics Inc. | Repros stopped study due to safety and FDA placed study on hold | Safety / toxicity |
| NCT01189253 | Doxorubicin Hydrochloride or Trabectedin in Treating Patients With Previously Untreated… | Phase 2 / Phase 3 | terminated | Aug 26, 2010 | European Organisation for Research and Treatment of Cancer - EORTC | Results of step1: none of the experimental arms fulfills expectations and the study will not… | Other (stated, no rule matched) |
| NCT00740597 | Intensity-Modulated Radiation Therapy in Treating Patients Undergoing Surgery for Stage… | Phase 2 | terminated | Aug 25, 2008 | City of Hope Medical Center | No patients were enrolled on the study | Enrollment / accrual |
| NCT00874302 | Safety and Efficacy of 25 and 50 mg Doses of Proellex® in Treating the Recurrence of… | Phase 3 | withdrawn | Apr 2, 2009 | Repros Therapeutics Inc. | Study terminated for safety and the FDA put the study on hold for safety. | Safety / toxicity |
| NCT00002863 | Cryosurgery in Treating Patients With Soft Tissue Sarcoma | Phase 1 | terminated | Jul 7, 2004 | University of Southern California | Insufficient Accrual | Enrollment / accrual |
| NCT00944476 | Application of Magnetic Resonance Fat-Free Imaging | — | terminated | Jul 23, 2009 | Memorial Sloan Kettering Cancer Center | Software issues not resolved. | Other (stated, no rule matched) |
| NCT00521092 | Sunitinib Malate in Treating East African Patients With Kaposi Sarcoma | Phase 2 | withdrawn | Aug 27, 2007 | National Cancer Institute (NCI) | No participants enrolled. | Enrollment / accrual |
| NCT01491594 | Eltrombopag for the Prevention of Chemotherapy Induced Thrombocytopenia | Phase 1 | terminated | Dec 14, 2011 | Duke University | Unable to accrue subjects to the study. | Enrollment / accrual |
| NCT01479023 | Evaluation of 64Cu-DOTA-U3-1287 in Subjects With Advanced Solid Tumors | Phase 1 | terminated | Nov 24, 2011 | Washington University School of Medicine | treatment was not working | Other (stated, no rule matched) |
| NCT01048723 | Study of RAD001 in Soft Tissue Extremity and/or Retroperitoneal Sarcomas | Phase 2 | terminated | Jan 14, 2010 | H. Lee Moffitt Cancer Center and Research Institute | Novartis terminated funding | Funding |
| NCT00976508 | Figitumumab Combined With Pegvisomant For Advanced Solid Tumors | Phase 1 | terminated | Sep 14, 2009 | Pfizer | See termination reason in detailed description. | Other (stated, no rule matched) |
| NCT01258634 | A Study of Pre-Operative Treatment of Newly-Diagnosed, Surgically-Resectable Osteosarcoma… | Phase 1 | terminated | Dec 13, 2010 | University of Chicago | PI no longer affiliated with institution; only 2 subjects enrolled | Enrollment / accrual |
| NCT00768742 | Safety and Effectiveness Study of RF Ablation of Uterine Fibroids to Reduce Menstrual…(FAST) | N/A | withdrawn | Oct 8, 2008 | Gynesonics | study revised and reinitiated under another protocol | Other (stated, no rule matched) |
| NCT00003292 | S9624 Ifosfamide in Treating Patients With Meningeal Tumors | Phase 2 | terminated | Jan 27, 2003 | SWOG Cancer Research Network | lack of accrual | Enrollment / accrual |
| NCT01697514 | A Study of LY2940680 in Pediatric Medulloblastoma or Rhabdomyosarcoma | Phase 1 | withdrawn | Oct 2, 2012 | Eli Lilly and Company | Trial stopped early for poor accrual. | Enrollment / accrual |
| NCT00334984 | Glutamine in Preventing Oral Mucositis in Patients Receiving Chemotherapy for Sarcoma | N/A | withdrawn | Jun 8, 2006 | Children's Oncology Group | Withdrawn due to inability to reach an acceptable agreement with industry sponsor | Other (stated, no rule matched) |
| NCT00002993 | Combination Chemotherapy in Treating Patients With Recurrent or Advanced Cancer of the… | Phase 2 | terminated | Sep 3, 2004 | Gynecologic Oncology Group | not stated | Not stated |
| NCT00334867 | Combination Chemotherapy With or Without Topotecan in Treating Patients With Newly… | Phase 3 | withdrawn | Jun 8, 2006 | Children's Oncology Group | withdrawn | Other (stated, no rule matched) |
| NCT00017160 | Combination Chemotherapy, Radiation Therapy, and Surgery in Treating Patients With… | Phase 2 | withdrawn | Jan 27, 2003 | Radiation Therapy Oncology Group | not stated | Not stated |
| NCT01112800 | Markers of Anthracycline-Related Cardiac Muscle Injury | — | withdrawn | Apr 28, 2010 | St. Jude Children's Research Hospital | not stated | Not stated |
| NCT01492569 | Acupuncture Point Stimulation for Treatment of Chemotherapy Nausea and Vomiting | N/A | withdrawn | Dec 15, 2011 | Stanford University | low accrual | Enrollment / accrual |
| NCT00006222 | EMD 121974 in Treating Patients With HIV-Related Kaposi's Sarcoma | Phase 1 | terminated | May 26, 2004 | National Cancer Institute (NCI) | Administratively complete. | Other (stated, no rule matched) |
| NCT00615628 | Inheritance of Osteosarcoma & Paget's Disease Through Chromosome 18: | — | terminated | Feb 14, 2008 | State University of New York - Upstate Medical University | low enrollment low enrollment | Enrollment / accrual |
| NCT00003156 | Topotecan in Treating Patients With Recurrent or Refractory Cancer of the Uterus | Phase 2 | terminated | Apr 7, 2004 | Gynecologic Oncology Group | not stated | Not stated |
| NCT00003316 | Gemcitabine in Treating Patients With Recurrent or Refractory Cancer of the Uterus | Phase 2 | terminated | Apr 9, 2004 | Gynecologic Oncology Group | not stated | Not stated |
| NCT00003624 | Amifostine in Treating Women With Ovarian, Peritoneal, Cervical, Fallopian Tube, Uterine,… | Phase 2 | terminated | Jun 16, 2004 | Gynecologic Oncology Group | not stated | Not stated |
| NCT00033644 | Combination Chemotherapy Plus Sargramostim in Treating Patients With Cancer of the Uterus | Phase 2 | terminated | Jan 27, 2003 | Gynecologic Oncology Group | not stated | Not stated |
| NCT00027911 | Vaccine Therapy and Sargramostim in Treating Patients With Soft Tissue Sarcoma | Phase 1 | terminated | Jan 27, 2003 | Columbia University | Departure of PI | Other (stated, no rule matched) |
| NCT00087191 | EF5 and Motexafin Lutetium in Detecting Tumor Cells in Patients With Abdominal or… | N/A | terminated | Jul 12, 2004 | National Cancer Institute (NCI) | Administratively complete. | Other (stated, no rule matched) |
| NCT00896961 | EF5 to Evaluate Tumor Hypoxia in Patients With High-Grade Soft Tissue Sarcoma or Mouth… | N/A | terminated | May 12, 2009 | National Cancer Institute (NCI) | Administratively complete. | Other (stated, no rule matched) |
| NCT00288444 | Interaction of Docetaxel and Lonafarnib in Patients With Advanced Cancer | Phase 1 | terminated | Feb 8, 2006 | Emory University | not stated | Not stated |
| NCT00014313 | Chemotherapy in Treating Patients With Metastatic Ewing's Sarcoma or Primitive… | Phase 2 | terminated | Jan 27, 2003 | European Organisation for Research and Treatment of Cancer - EORTC | low accrual | Enrollment / accrual |
| NCT00496080 | Doppler-Guided Uterine Artery Occlusion (DUAO) Device for Fibroid Related Bleeding(DUAO) | N/A | terminated | Jul 4, 2007 | Ethicon, Inc. | Trial terminated early due to results from a similar study. | Other (stated, no rule matched) |
| NCT00079950 | Efficacy and Safety Evaluation of Pegamotecan (PEG-camptothecin) in Advanced or… | Phase 2 | suspended | Mar 22, 2004 | Enzon Pharmaceuticals, Inc. | not stated | Not stated |
| NCT00427583 | Imatinib Mesylate Treatment of Patients With Malignant Peripheral Nerve Sheath Tumors | Phase 2 / Phase 3 | terminated | Jan 29, 2007 | Novartis Pharmaceuticals | stopped due to slow recruitment and no effect | Enrollment / accrual |
| NCT00508339 | Functional Outcomes Following Limb Sparing Surgery for Sarcoma Patients | — | withdrawn | Jul 27, 2007 | M.D. Anderson Cancer Center | not stated | Not stated |
| NCT01296659 | Study of Oral Ridaforolimus in Combination With Standard Chemotherapy for Soft Tissue… | Phase 1 | withdrawn | Feb 15, 2011 | The University of Texas Health Science Center at San Antonio | Principal Investigator left institution. | Investigator |
| NCT00253552 | G-CSF-Treated Donor Bone Marrow Transplant in Treating Patients With Hematologic Disorders | N/A | terminated | Nov 15, 2005 | OHSU Knight Cancer Institute | Terminated at request of PI as study was outdated. | Other (stated, no rule matched) |
| NCT00023790 | Photodynamic Therapy in Treating Patients With Skin Cancer or Solid Tumors Metastatic to… | Phase 1 | terminated | Jan 27, 2003 | Case Comprehensive Cancer Center | slow accrual | Enrollment / accrual |
| NCT00496067 | Uterine Artery Occlusion for Fibroid Related Bleeding | N/A | terminated | Jul 4, 2007 | Ethicon, Inc. | Data required further pilot work to be undertaken. | Other (stated, no rule matched) |
| NCT01140555 | A Pilot Study to Determine Optimal Procedure Steps to Obtain and Maintain Uterine Artery… | N/A | terminated | Jun 9, 2010 | Ethicon, Inc. | Further internal evaluation of the device was required. | Other (stated, no rule matched) |
| NCT00568464 | Study on VCD/IE in the Patients With Ewing's Sarcoma Family of Tumors (ESFT) | Phase 2 | terminated | Dec 6, 2007 | Fudan University | The enrollment is slower than expected | Enrollment / accrual |
| NCT00584207 | Radiofrequency Ablation of Uterine Fibroids | Early Phase 1 | terminated | Jan 2, 2008 | University of California, Davis | Unsufficient referrals for recruitment | Enrollment / accrual |
| NCT00162695 | Rhabdomyosarcoma and Malignant Soft Tissue Tumours of Childhood | Phase 3 | terminated | Sep 13, 2005 | Gustave Roussy, Cancer Campus, Grand Paris | not stated | Not stated |
Stop reasons are registrant-reported free text and are displayed verbatim (truncated; hover for the full text). Categories come from explicit keyword rules and are never inferred from the study design, sponsor or outcome; a study that stopped for several reasons is filed under the first rule that matched. A TERMINATED status does not imply a negative result.
Data updated 22 days agoSource updated Aug 21, 2014source: clinicaltrials