Clinical trial · Interventional
Acupuncture Point Stimulation for Treatment of Chemotherapy Nausea and Vomiting
NCT01492569CI-TRIAL-00010693withdrawnN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Why stopped (as posted): low accrual
Summary
Brief summary (as posted)
This randomized pilot clinical trial studies giving acupuncture in reducing nausea and vomiting in patients undergoing chemotherapy. Pressing and stimulating nerves at an acupuncture point on the inside of the wrist may help control nausea and vomiting during chemotherapy.
Conditions
Conditions (5)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Childhood Acute Lymphoblastic Leukemia | Childhood Acute Lymphoblastic Leukemia | ONTOLOGY_EXACT | 0.98 |
| Childhood Acute Myeloid Leukemia/Other Myeloid Malignancies | — | UNRESOLVED | — |
| Ewing Sarcoma | Ewing Sarcoma | ONTOLOGY_EXACT | 0.98 |
| Osteosarcoma | Osteosarcoma | ONTOLOGY_EXACT | 0.90 |
| Vomiting in Infants and/or Children | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| electroacupuncture therapy | Procedure | — | UNRESOLVED |
| questionnaire administration | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Arm I (TAPS at the P6 point)
- description
- Patients undergo TAPS at the true acupuncture point (P6) 30 minutes prior to first chemotherapy infusion and then four times a day for 20 minutes every 2 hours at 8am, 10am, 12pm, and 2pm. Patients then crossover to Arm II for the second course of chemotherapy.
- interventionNames
- Other: questionnaire administration
- Procedure: electroacupuncture therapy
- type
- SHAM_COMPARATOR
- label
- Arm II (TAPS at a non-P6 point)
- description
- Patients undergo TAPS at a sham non-acupuncture point 30 minutes prior to first chemotherapy infusion and then four times a day for 20 minutes every 2 hours at 8am, 10am, 12pm, and 2pm. Patients then crossover to Arm I for the second course of chemotherapy.
- interventionNames
- Procedure: electroacupuncture therapy
- Other: questionnaire administration
Primary outcomes (2)
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 8 Years
- Maximum age
- 21 Years
Show eligibility criteria text
Inclusion Criteria: * Patient with a planned admission for at least 24 hours for highly emetogenic or moderately emetogenic chemotherapy at Lucile Packard Children's Hospital or Packard El Camino. * Planned to undergo at least 2 more cycles of chemotherapy. * Can include but not limited to: children with high risk ALL, AML, Ewing's Sarcoma, Osteosarcoma * History of vomiting with prior cycles of chemotherapy (2 episodes of emesis at minimum) despite use of conventional antiemetic medications. * Age 8-21. * Parent must be able to understand and willing to sign written informed consent document. Exclusion Criteria: * Prior knowledge of acupuncture or experience with acupuncture or acupressure. * There will be no restrictions regarding use of other Investigational Agents. * Comorbid Diseases: * Diagnosis of any cardiac condition (cardiomyopathy, arrhythmia, pacemaker placement). * Any diagnosis requiring pediatric intensive care unit admission. * Patients with brain tumor, brain metastasis (these patients often require radiation and surgery in addition to chemotherapy which may confound the results) * Concomitant radiation therapy during current chemotherapy cycle. * Developmental delay patients with allergy to tape or leads will be excluded from the study. * Pregnant patients will be excluded from the study. * Cancer survivors will not be excluded from the study as long as they are undergoing chemotherapy treatment for their current cancer therapy. * HIV-positive patients will not be excluded.
References
Publications (0)
Data not yet available
No reference posted for this study.