Loading clinical trials…
Loading clinical trials…
Clinical trials · failure tracking
Oncology studies whose overall status is TERMINATED, WITHDRAWN or SUSPENDED on ClinicalTrials.gov, with the stop reason exactly as the registrant posted it. A category is attached only when an explicit keyword rule matches the text; CancerIndex never infers why a study stopped.
154 stopped studies mapped to Ovarian Carcinoma and descendants · 90% state a reason
Over the 154 studies matching the cancer, status and year filters (the category filter does not change this chart). Each study is counted once, in the first matching category; greyed bars are studies whose text matched no rule or was empty.
Computed
A category is assigned when one of its keywords appears in the posted text (case-insensitive, whole words). Rules are tested in this order and the first match wins; every match is kept in the API (reasonMatches).
| NCT | Title | Phase | Status | First posted | Lead sponsor | Why stopped (as posted) | Category |
|---|---|---|---|---|---|---|---|
| NCT01334047 | Trial of Vaccine Therapy in Recurrent Platinum Sensitive Ovarian Cancer Patients | Phase 1 / Phase 2 | terminated | Apr 12, 2011 | Steinar Aamdal | The study needed to be terminated due to new knowledge about cancer vaccines. A new protocol with… | Other (stated, no rule matched) |
| NCT02947152 | HKT288 in Solid Tumors, Including Epithelial Ovarian Cancer and Renal Cell Carcinoma | Phase 1 | terminated | Oct 27, 2016 | Novartis Pharmaceuticals | not stated | Not stated |
| NCT03957096 | A Safety Study of SGN-CD47M in Patients With Solid Tumors | Phase 1 | terminated | May 21, 2019 | Seagen Inc. | Sponsor decision based on portfolio prioritization | Sponsor / business decision |
| NCT01249443 | Paclitaxel and Carboplatin in Treating Patients With Metastatic or Recurrent Solid Tumors… | Phase 1 | terminated | Nov 29, 2010 | AIDS Malignancy Consortium | Inadequate accrual rate | Enrollment / accrual |
| NCT01312376 | Autologous T-Cells Combined With Autologous OC-DC Vaccine in Ovarian Cancer | Phase 1 | terminated | Mar 10, 2011 | Abramson Cancer Center at Penn Medicine | not stated | Not stated |
| NCT02487849 | HIPEC After Secondary Cytoreductive Operation in Patients With Platinum-sensitive…(HIPEC) | Phase 2 | withdrawn | Jul 2, 2015 | Krankenhaus Barmherzige Schwestern Linz | actually limited personnel ressources | Other (stated, no rule matched) |
| NCT02012192 | GANNET53: Ganetespib in Metastatic, p53-mutant, Platinum-resistant Ovarian Cancer | Phase 1 / Phase 2 | terminated | Dec 16, 2013 | Medical University Innsbruck | production of IMP has stopped | Other (stated, no rule matched) |
| NCT01159067 | Deferasirox for Treating Patients Who Have Undergone Allogeneic Stem Cell Transplant and… | Phase 2 | terminated | Jul 9, 2010 | City of Hope Medical Center | Low enrollment | Enrollment / accrual |
| NCT02943317 | Study to Investigate the Safety, Pharmacokinetics, Pharmacodynamics and Preliminary… | Phase 1 | terminated | Oct 24, 2016 | Verastem, Inc. | The study was terminated upon completion of escalation phase, prior to opening expansion cohorts | Other (stated, no rule matched) |
| NCT02575807 | Safety and Efficacy of CRS-207 With Epacadostat in Platinum Resistant Ovarian, Fallopian…(SEASCAPE) | Phase 1 / Phase 2 | terminated | Oct 15, 2015 | Aduro Biotech, Inc. | Study was stopped due to low enrollment and lack of clinical activity. | Enrollment / accrual |
| NCT02948101 | PD 0360324 and Cyclophosphamide in Treating Patients With Recurrent High-Grade Epithelial… | Phase 2 | withdrawn | Oct 28, 2016 | M.D. Anderson Cancer Center | PI's request | Other (stated, no rule matched) |
| NCT02050009 | Metformin Hydrochloride, Carboplatin, and Paclitaxel in Treating Patients With Recurrent… | Phase 1 | withdrawn | Jan 30, 2014 | Fox Chase Cancer Center | study was never opened to accrual | Enrollment / accrual |
| NCT02530606 | Photoacoustic Imaging in Detecting Ovarian or Fallopian Tube Cancer | N/A | withdrawn | Aug 21, 2015 | Stanford University | Efficacy | Efficacy / futility |
| NCT00039091 | Monoclonal Antibody Therapy in Treating Patients With Ovarian Epithelial Cancer,… | Phase 1 | terminated | Jan 27, 2003 | National Cancer Institute (NCI) | not stated | Not stated |
| NCT02878980 | An Exercise Intervention Trial to Reduce Symptoms & Improve Clinical Outcomes of… | N/A | withdrawn | Aug 25, 2016 | City of Hope Medical Center | Feasibility issues | Other (stated, no rule matched) |
| NCT00899093 | YKL-40 in Serum Samples From Patients With Newly Diagnosed Stage III-IV Ovarian… | — | terminated | May 12, 2009 | Gynecologic Oncology Group | not stated | Not stated |
| NCT01275664 | Granisetron, Aprepitant, and Dexamethasone in Preventing Nausea and Vomiting in Patients… | N/A | terminated | Jan 12, 2011 | Gynecologic Oncology Group | Study terminated due to no patient population available | Other (stated, no rule matched) |
| NCT02412124 | Peer-to-Peer Support Program in Improving Quality of Life Outcomes in Patients With… | N/A | terminated | Apr 8, 2015 | City of Hope Medical Center | Feasibility issues | Other (stated, no rule matched) |
| NCT02833506 | Sirolimus and Vaccine Therapy in Treating Patients With Stage II-IV Ovarian, Fallopian… | Phase 1 | withdrawn | Jul 14, 2016 | Roswell Park Cancer Institute | production of adjuvant to be used with vaccine was discontinued by sponsor | Other (stated, no rule matched) |
| NCT01773889 | A Trial of Intravenous Denileukin Diftitox Plus Subcutaneous Pegylated IFNα-2A in Stage… | Phase 2 | terminated | Jan 23, 2013 | The University of Texas Health Science Center at San Antonio | Lack of funding | Funding |
| NCT02708511 | Copper Cu 64-DOTA-B-Fab PET/CT in Imaging Patients With Ovarian and Breast Cancer | Phase 1 | terminated | Mar 15, 2016 | Sanjiv Sam Gambhir | not stated | Not stated |
| NCT01936974 | (PGA) for Platinum-resistant/Refractory, Paclitaxel-Pretreated Recurrent Ovarian and…(PGA) | Phase 2 | terminated | Sep 6, 2013 | Western Regional Medical Center | PI Decision | Other (stated, no rule matched) |
| NCT00004221 | Combination Chemotherapy and Peripheral Stem Cell Transplantation in Treating Patients… | Phase 2 | terminated | Aug 25, 2003 | Gynecologic Oncology Group | not stated | Not stated |
| NCT00551265 | Oregovomab With or Without Cyclophosphamide in Treating Patients With Stage III or Stage… | N/A | withdrawn | Oct 30, 2007 | Gynecologic Oncology Group | not stated | Not stated |
| NCT01681368 | Birinapant for Advanced Ovarian, Fallopian Tube, and Peritoneal Cancer | Phase 2 | terminated | Sep 7, 2012 | National Cancer Institute (NCI) | Accrual was terminated for lack of a clinical benefit. | Enrollment / accrual |
| NCT02742428 | Preoperative Ascites Drainage Versus Standard Care for Patients With Advanced Ovarian… | N/A | suspended | Apr 19, 2016 | Gdynia Oncology Center | The protocol will be discussed and consulted. Potentially will resume. | Other (stated, no rule matched) |
| NCT01494012 | Phase I Stereotactic Body Radiation for Metastatic or Recurrent Platinum-Resistant… | Phase 1 | terminated | Dec 16, 2011 | Stanford University | low accrual | Enrollment / accrual |
| NCT01138137 | N-acetylcysteine Given IV With Cisplatin and Paclitaxel in Patients With Ovarian Cancer | Phase 1 | withdrawn | Jun 7, 2010 | OHSU Knight Cancer Institute | No funding was available for the cost of the IV N-acetylcysteine (NAC). | Funding |
| NCT02218502 | Study Into a New Diagnostic Tool (Simple Ultrasound-based Rules) in Patients With Adnexal…(SUBSONiC) | N/A | terminated | Aug 18, 2014 | Maastricht University Medical Center | interim analysis showed incorrect use of simple rules | Efficacy / futility |
| NCT01521143 | Cvac as Maintenance Treatment in Patients With Epithelial Ovarian Cancer in Complete…(CANVAS) | Phase 2 | terminated | Jan 30, 2012 | Prima BioMed Ltd | The study was terminated due to company restructuring and changes in drug development priorities. | Sponsor / business decision |
| NCT02035345 | Slowed Carboplatin Infusion for Ovarian Cancer Patients Receiving Carboplatin Re-Treatment | Phase 4 | terminated | Jan 14, 2014 | Massachusetts General Hospital | Extended Carboplatin Infusion did not Reduce Frequency of Hypersensitivity Reactions | Other (stated, no rule matched) |
| NCT02083536 | LDFWART With Docetaxel in Patients With Platinum-Resistant Recurrent Ovarian Carcinoma | Phase 1 | withdrawn | Mar 11, 2014 | University of Miami | Study voluntarily stopped by Principal Investigator due to lack of accrual. | Investigator |
| NCT02627430 | Talazoparib and HSP90 Inhibitor AT13387 in Treating Patients With Metastatic Advanced… | Phase 1 | withdrawn | Dec 11, 2015 | National Cancer Institute (NCI) | Other - Protocol moved to Withdrawn | Other (stated, no rule matched) |
| NCT02470559 | Activated T-cell Therapy, Low-Dose Aldesleukin, and Sargramostim in Treating Patients… | Phase 1 | withdrawn | Jun 12, 2015 | Barbara Ann Karmanos Cancer Institute | Study did not accrue any participants, the PI has left the institution. | Enrollment / accrual |
| NCT01840943 | A Study to Compare CAELYX With Topotecan HCL in Patients With Recurrent Epithelial… | Phase 3 | terminated | Apr 26, 2013 | Xian-Janssen Pharmaceutical Ltd. | the study was terminated due to medication supply issue from current manufacturer | Drug supply |
| NCT00313612 | Oxaliplatin and Topotecan in Advance Ovarian Cancer | Phase 2 | terminated | Apr 12, 2006 | National Cancer Institute (NCI) | not stated | Not stated |
| NCT01175772 | Maintenance Treatment for Ovarian Carcinoma in Remission by an Antiangiogenic Treatment… | Phase 2 | terminated | Aug 5, 2010 | HaEmek Medical Center, Israel | Due to change in the national policy of medications | Other (stated, no rule matched) |
| NCT00053235 | Research Study in Patients With Advanced Ovarian Epithelial Cancer | — | withdrawn | Jan 28, 2003 | Gynecologic Oncology Group | not stated | Not stated |
| NCT01200797 | SJG-136 in Treating Patients With Epithelial Ovarian, Primary Peritoneal, or Fallopian… | Phase 2 | terminated | Sep 14, 2010 | National Cancer Institute (NCI) | Slow accrual was the reason for study termination. | Enrollment / accrual |
| NCT00659399 | Feasibility Study of Short Term Fondaparinux (Arixtra) in Chemotherapy-Pretreated Ovarian… | Phase 1 | withdrawn | Apr 16, 2008 | NYU Langone Health | Low accrual | Enrollment / accrual |
| NCT00312650 | Doxil and Gemcitabine in Recurrent Ovarian Cancer | Phase 2 | terminated | Apr 10, 2006 | Women and Infants Hospital of Rhode Island | not stated | Not stated |
| NCT01492920 | Acetyl-L-Carnitine Hydrochloride in Preventing Peripheral Neuropathy in Patients With… | Phase 3 | withdrawn | Dec 15, 2011 | Gynecologic Oncology Group | Withdrawn | Other (stated, no rule matched) |
| NCT01927393 | Palliative Care in Improving Quality of Life and Symptoms in Patients With Stage III-IV… | N/A | withdrawn | Aug 22, 2013 | City of Hope Medical Center | Study was not funded | Funding |
| NCT01095367 | Seprafilm™ for the Prevention of Intraperitoneal Adhesions and Improved Delivery of… | N/A | terminated | Mar 30, 2010 | University of British Columbia | due to company changes and lack of funding-unlikely to have sufficient numbers to analyze… | Funding |
| NCT01233505 | Veliparib, Oxaliplatin, and Capecitabine in Treating Patients With Advanced Solid Tumors | Phase 1 | terminated | Nov 3, 2010 | National Cancer Institute (NCI) | not stated | Not stated |
| NCT01202890 | Study of Revlimid With Doxil and Avastin for Patients With Platinum Resistant Ovarian… | Phase 1 | terminated | Sep 16, 2010 | New Mexico Cancer Research Alliance | Terminated due to inadequate rate of accrual. | Enrollment / accrual |
| NCT01982487 | Vaccine Therapy and IDO1 Inhibitor INCB024360 in Treating Patients With Epithelial… | Phase 1 / Phase 2 | withdrawn | Nov 13, 2013 | Roswell Park Cancer Institute | not stated | Not stated |
| NCT00942838 | Whole Abdomen Radiation in Conjunction With Intraperitoneal Chemotherapy for the…(WAR) | Phase 1 | withdrawn | Jul 21, 2009 | University of Utah | PI decision due to under accrual. | Enrollment / accrual |
| NCT00091195 | Depsipeptide (Romidepsin) in Treating Patients With Recurrent Ovarian Epithelial or… | Phase 2 | terminated | Sep 9, 2004 | National Cancer Institute (NCI) | Administratively complete. | Other (stated, no rule matched) |
| NCT00087191 | EF5 and Motexafin Lutetium in Detecting Tumor Cells in Patients With Abdominal or… | N/A | terminated | Jul 12, 2004 | National Cancer Institute (NCI) | Administratively complete. | Other (stated, no rule matched) |
Stop reasons are registrant-reported free text and are displayed verbatim (truncated; hover for the full text). Categories come from explicit keyword rules and are never inferred from the study design, sponsor or outcome; a study that stopped for several reasons is filed under the first rule that matched. A TERMINATED status does not imply a negative result.
Data updated 23 days agoSource updated Feb 26, 2021source: clinicaltrials