Loading clinical trials…
Loading clinical trials…
Clinical trials · failure tracking
Oncology studies whose overall status is TERMINATED, WITHDRAWN or SUSPENDED on ClinicalTrials.gov, with the stop reason exactly as the registrant posted it. A category is attached only when an explicit keyword rule matches the text; CancerIndex never infers why a study stopped.
1,359 stopped studies mapped to Non-Hodgkin Lymphoma and descendants · 89% state a reason
Over the 1,359 studies matching the cancer, status and year filters (the category filter does not change this chart). Each study is counted once, in the first matching category; greyed bars are studies whose text matched no rule or was empty.
Computedrules ci-stop-reasons-v1 · keyword matching only
A category is assigned when one of its keywords appears in the posted text (case-insensitive, whole words). Rules are tested in this order and the first match wins; every match is kept in the API (reasonMatches).
| NCT | Title | Phase | Status | First posted | Lead sponsor | Why stopped (as posted) | Category |
|---|---|---|---|---|---|---|---|
| NCT02653989 | Efficacy and Safety Study of MDV9300 in Patients With Relapsed or Refractory Diffuse… | Phase 2 | withdrawn | Jan 13, 2016 | Medivation, Inc. | not stated | Not stated |
| NCT01745354 | Immunostimulatory CpG SD-101 + RT in Recurrent/Progressive Lymphoma After Allogeneic… | Phase 1 | terminated | Dec 10, 2012 | Robert Lowsky | Accrual issues - Slow accrual | Enrollment / accrual |
| NCT01704742 | Prospective Study of Lymphoproliferative Diseases | — | withdrawn | Oct 11, 2012 | West Virginia University | Protocol not considered a clinical trial for registration purposes; no subjects enrolled to date… | Enrollment / accrual |
| NCT02756663 | Panobinostat in Combination With Carfilzomib and Dexamethasone in Relapsed or Relapsed…(PANORAMA-5) | Phase 2 | withdrawn | Apr 29, 2016 | Novartis Pharmaceuticals | not stated | Not stated |
| NCT00255684 | Fludarabine, Cyclophosphamide, and Total-Body Irradiation Followed by Cyclosporine and… | N/A | terminated | Nov 21, 2005 | University of Rochester | low accrual | Enrollment / accrual |
| NCT01423539 | A Study of Navitoclax in Addition to Bendamustine and Rituximab in Patients With Relapsed… | Phase 2 | withdrawn | Aug 26, 2011 | Genentech, Inc. | The NAVIGATE study has been terminated due to non-safety related reasons. | Safety / toxicity |
| NCT01609036 | An Observational Study of MabThera/Rituxan (Rituximab) in Patients With Follicular… | — | terminated | May 31, 2012 | Hoffmann-La Roche | not stated | Not stated |
| NCT01724294 | An Observational Study of MabThera/Rituxan (Rituximab) in Combination With CHOP… | — | terminated | Nov 9, 2012 | Hoffmann-La Roche | not stated | Not stated |
| NCT02020941 | Carfilzomib in Treating Patients With Multiple Myeloma in First Relapse or Refractory to… | Phase 2 | terminated | Dec 25, 2013 | Attaya Suvannasankha | Slow accrual | Enrollment / accrual |
| NCT01541072 | Lymphocyte Reconstitution After Administration of Pegfilgrastim Versus Filgrastim After…(PALM2) | N/A | terminated | Feb 29, 2012 | Centre Leon Berard | Number of enrolled patients was insufficient during planned inclusion time. | Enrollment / accrual |
| NCT02115126 | Phase II Trial to Evaluate an EBV-derived Dendritic Cell Vaccine in Autologous Stem Cell… | Phase 2 | withdrawn | Apr 15, 2014 | David Rizzieri, MD | not stated | Not stated |
| NCT01186458 | Fludarabine, Velcade and Rituximab for Relapsed or Refractory Follicular Non-Hodgkin… | Phase 2 | terminated | Aug 23, 2010 | Hoosier Cancer Research Network | Slow accrual | Enrollment / accrual |
| NCT01144403 | A Study of MabThera (Rituximab) Addition to Regularly Prescribed Chemotherapy in Patients… | Phase 2 | terminated | Jun 15, 2010 | Hoffmann-La Roche | not stated | Not stated |
| NCT01699581 | Assessment of Impact Nutritional Program During Autologous Stem Cell Transplant | Phase 2 | terminated | Oct 3, 2012 | Greg Monohan | Research cancelled following interim analysis | Efficacy / futility |
| NCT00788606 | R-CHOP-B Bevacizumab for Diffuse Large B Cell Lymphoma | Phase 2 | terminated | Nov 11, 2008 | Royal Marsden NHS Foundation Trust | Toxicity and efficacy data from another trial | Safety / toxicity |
| NCT00912899 | A Study of Noscapine HCl (CB3304 ) in Patients With Relapsed or Refractory Multiple… | Phase 1 | terminated | Jun 3, 2009 | Cougar Biotechnology, Inc. | Terminated early due to lack of clinical response. | Other (stated, no rule matched) |
| NCT02141100 | Study of 6-Thioguanine in Combination With 6-Mercaptopurine During Maintenance Therapy of… | Phase 1 / Phase 2 | withdrawn | May 19, 2014 | Kjeld Schmiegelow | not stated | Not stated |
| NCT02605356 | Phase 1b/2 Study Testing Radium-223 Dichloride/Bortezomib/Dexamethasone Combination in… | Phase 1 / Phase 2 | withdrawn | Nov 16, 2015 | Bayer | Study restarted under new study number 18987 | Other (stated, no rule matched) |
| NCT01423760 | Common Safety Follow-up Trial of Tecemotide (L-BLP25) | N/A | terminated | Aug 26, 2011 | Merck KGaA, Darmstadt, Germany | The study is terminated prematurely as the sponsor decided to discontinue program with Tecemotide… | Sponsor / business decision |
| NCT01598558 | Assessing Response to Treatment in Non-Hodgkin's Lymphoma Patients Using… | N/A | withdrawn | May 15, 2012 | Sanjiv Sam Gambhir | Accrual issues - Low Accrual | Enrollment / accrual |
| NCT00278265 | Methotrexate Followed by Fludarabine in Patients With T-Cell Large Granular Lymphocytic… | Phase 2 | terminated | Jan 18, 2006 | German CLL Study Group | slow recruitment | Enrollment / accrual |
| NCT01829971 | A Multicenter Phase I Study of MRX34, MicroRNA miR-RX34 Liposomal Injection | Phase 1 | terminated | Apr 11, 2013 | Mirna Therapeutics, Inc. | Five immune related serious adverse events | Safety / toxicity |
| NCT02573935 | Clarithromycin in Multiple Myeloma Induction Therapy(CLAIM) | Phase 2 | terminated | Oct 12, 2015 | Henrik Gregersen | Suspected side effects to the combination of clarithromycin and VCD (bortezomib, cyclophosphamide… | Other (stated, no rule matched) |
| NCT01985477 | Revlimid / All-Trans Retinoic Acid (ATRA) / Dexamethasone in Relapsed/Refractory Multiple… | Phase 1 | terminated | Nov 15, 2013 | M.D. Anderson Cancer Center | Terminated Phase I due to slow accrual without progression to Phase II. | Enrollment / accrual |
| NCT01121757 | Epigenetic Modulation in Relapsed/Refractory Follicular Lymphoma and Marginal Zone… | Phase 2 | terminated | May 12, 2010 | Duke University | The study closed temporarily in February 2012 pending analysis of samples collected. In October,… | Other (stated, no rule matched) |
| NCT00984828 | Randomized Study of Velcade-based Regimen With Autologous Stem Cell Transplantation in… | Phase 2 / Phase 3 | terminated | Sep 25, 2009 | Shanghai Jiao Tong University School of Medicine | Very slow recruitment | Enrollment / accrual |
| NCT02808091 | Bortezomib With Combination of Gemcitabine, Ifosfamide and Oxaliplatin in Untreated NK/T…(Gifox-B) | Phase 2 | terminated | Jun 21, 2016 | National Cancer Centre, Singapore | Slow recruitment | Enrollment / accrual |
| NCT02230917 | A Phase IIa Study of Sotatercept on Bone Mass and Turnover in Patients With Multiple… | Phase 2 | withdrawn | Sep 3, 2014 | Rebecca Silbermann | not stated | Not stated |
| NCT02281279 | Rituximab, Romidepsin, and Lenalidomide in Treating Patients With Recurrent or Refractory… | Phase 1 / Phase 2 | withdrawn | Nov 3, 2014 | Mayo Clinic | not stated | Not stated |
| NCT00112723 | Flavopiridol in Treating Patients With Relapsed or Refractory Lymphoma or Multiple Myeloma | Phase 1 / Phase 2 | terminated | Jun 3, 2005 | National Cancer Institute (NCI) | Administratively Complete | Other (stated, no rule matched) |
| NCT02640833 | A Study of Duvelisib and Venetoclax in Subjects With Relapsed or Refractory Chronic… | Phase 1 | withdrawn | Dec 29, 2015 | AbbVie | Study Stopped | Other (stated, no rule matched) |
| NCT01078974 | Pomalidomide, Dexamethasone and Rituximab in Waldenstrom's Macroglobulinemia | Phase 1 | terminated | Mar 2, 2010 | Steven P. Treon, MD, PhD | Safety concerns (IgM Flare) | Safety / toxicity |
| NCT01096810 | Study of TBL 12 Sea Cucumber Extract for Patients With Untreated Asymptomatic Myeloma | Phase 2 | terminated | Mar 31, 2010 | Jagannath, Sundar, M.D. | The research is permanently closed to enrollment. | Enrollment / accrual |
| NCT02739594 | Comparison of Ibandronate - Zoledronate Regarding Nephrotoxicity in Multiple Myeloma(COMPARE) | Phase 3 | terminated | Apr 15, 2016 | Hoffmann-La Roche | Slow recruitment | Enrollment / accrual |
| NCT01652014 | Single or Double Donor Umbilical Cord Blood Transplant in Treating Patients With… | Phase 2 | withdrawn | Jul 27, 2012 | University of Medicine and Dentistry of New Jersey | Funding unavailable | Funding |
| NCT02046928 | Safety, Tolerability and Efficacy of A6 in Patients With Chronic Lymphocytic Leukemia… | Phase 2 | terminated | Jan 28, 2014 | Ångstrom Pharmaceuticals | Slow enrollment | Enrollment / accrual |
| NCT02447055 | Allogeneic Stem Cell Transplantation for Patients With Multiple Myeloma | Early Phase 1 | withdrawn | May 18, 2015 | Washington University School of Medicine | not stated | Not stated |
| NCT00983346 | Effect of Low Dose Bortezomib on Bone Formation in Smoldering Myeloma Patients | Phase 2 | terminated | Sep 24, 2009 | University of Utah | Lab Staff that was required left the institution, therefore accrual closed prematurely | Enrollment / accrual |
| NCT01144754 | Observational Study of Diffuse Large B Cell Primary Breast Lymphomas Treated With RCHOP… | — | terminated | Jun 16, 2010 | Stanford University | Low Accrual | Enrollment / accrual |
| NCT01556828 | Analysis of Cutaneous and Hematologic Disorders by High-Throughput Nucleic Acid Sequencing | — | terminated | Mar 16, 2012 | Stanford University | not stated | Not stated |
| NCT02273856 | Multicentre Registry of Treatments and Outcomes in Patients With Chronic Lymphocytic…(NADIR) | — | terminated | Oct 24, 2014 | Astellas Pharma International B.V. | The study was terminated due to insufficient subject enrollment and very slow enrollment. | Enrollment / accrual |
| NCT01536067 | Ofatumumab and Bortezomib in Treating Patients With Previously Untreated Waldenstrom… | Phase 2 | terminated | Feb 20, 2012 | Roswell Park Cancer Institute | funding was withdrawn | Funding |
| NCT02080416 | Nelfinavir for the Treatment of Gammaherpesvirus-Related Tumors | Early Phase 1 | terminated | Mar 6, 2014 | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | Very slow accrual; terminated to allow resources to be utilized more effectively on other studies.… | Enrollment / accrual |
| NCT01658904 | Carfilzomib and Stem Cell Transplant for Plasma Cell Myeloma | Phase 1 / Phase 2 | terminated | Aug 7, 2012 | National Cancer Institute (NCI) | study closed prematurely because investigator left National Institutes of Health | Investigator |
| NCT01182233 | Total Skeletal Irradiation in Multiple Myeloma Before Second Autologous Hematopoietic… | Phase 1 | terminated | Aug 16, 2010 | University of Rochester | low enrollment | Enrollment / accrual |
| NCT01807286 | Pomalidomide With Melphalan and Dexamethasone for Untreated Systemic AL Amyloidosis | Phase 1 | terminated | Mar 8, 2013 | M.D. Anderson Cancer Center | Sponsor requested termination | Other (stated, no rule matched) |
| NCT02735876 | A Study of Acalabrutinib in Combination With Rituximab Versus Ibrutinib Versus… | Phase 3 | withdrawn | Apr 13, 2016 | Acerta Pharma BV | not stated | Not stated |
| NCT00892346 | Single Autologous Stem Cell Transplantation Followed by Maintenance Therapy as Front-line… | Phase 3 | suspended | May 4, 2009 | Shanghai Jiao Tong University School of Medicine | No avaliability of melphlan in mainland China | Other (stated, no rule matched) |
| NCT01501370 | Vorinostat Plus Lenalidomide and Dexamethasone or Lenalidomide Plus Dexamethasone in…(ZLd_Ld) | Phase 2 | withdrawn | Dec 29, 2011 | Tiziana Marangon | not stated | Not stated |
| NCT00579111 | Reduced Intensity Preparative Regimen Followed by Stem Cell Transplant (FAB) | Phase 1 / Phase 2 | terminated | Dec 21, 2007 | Baylor College of Medicine | slow accrual | Enrollment / accrual |
Stop reasons are registrant-reported free text and are displayed verbatim (truncated; hover for the full text). Categories come from explicit keyword rules and are never inferred from the study design, sponsor or outcome; a study that stopped for several reasons is filed under the first rule that matched. A TERMINATED status does not imply a negative result.
Data updated 23 days agoSource updated Nov 25, 2016source: clinicaltrials