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Clinical trials · failure tracking
Oncology studies whose overall status is TERMINATED, WITHDRAWN or SUSPENDED on ClinicalTrials.gov, with the stop reason exactly as the registrant posted it. A category is attached only when an explicit keyword rule matches the text; CancerIndex never infers why a study stopped.
380 stopped studies mapped to Malignant Uterine Neoplasm and descendants · 86% state a reason
Over the 380 studies matching the cancer, status and year filters (the category filter does not change this chart). Each study is counted once, in the first matching category; greyed bars are studies whose text matched no rule or was empty.
Computedrules ci-stop-reasons-v1 · keyword matching only
A category is assigned when one of its keywords appears in the posted text (case-insensitive, whole words). Rules are tested in this order and the first match wins; every match is kept in the API (reasonMatches).
| NCT | Title | Phase | Status | First posted | Lead sponsor | Why stopped (as posted) | Category |
|---|---|---|---|---|---|---|---|
| NCT03902379 | Web-Based Coping and Communication Skills Intervention in Improving Psychological… | N/A | withdrawn | Apr 4, 2019 | Rutgers, The State University of New Jersey | The study was never initiated, no patients were enrolled. It has been closed with the IRB. | Enrollment / accrual |
| NCT03572478 | Rucaparib and Nivolumab in Patients With Prostate or Endometrial Cancer | Phase 1 / Phase 2 | terminated | Jun 28, 2018 | University of Chicago | The study was terminated due to lack of efficacy. | Efficacy / futility |
| NCT00285415 | A Phase II Evaluation of Docetaxel and Carboplatin Followed by Tumor Volume Directed… | Phase 2 | terminated | Feb 2, 2006 | Carilion Clinic | Investigator abruptly left Carilion. | Investigator |
| NCT03042897 | Exercise and Diet Intervention in Promoting Weight Loss in Obese Patients With Stage I… | N/A | withdrawn | Feb 3, 2017 | University of Southern California | PI left institution | Investigator |
| NCT01097239 | Examining the Role of Transrectal High Intensity Focused Ultrasound (HIFU) in Rectal… | Phase 1 / Phase 2 | withdrawn | Apr 1, 2010 | Imperial College London | Failure to recruit. | Enrollment / accrual |
| NCT00506779 | Gleevec/Taxol for Patients With Uterine Papillary Serous Carcinoma | Phase 1 / Phase 2 | terminated | Jul 25, 2007 | M.D. Anderson Cancer Center | the study was terminated early due to poor enrollment | Enrollment / accrual |
| NCT04197219 | Pembrolizumab With Axitinib in Recurrent Endometrial Cancer | Phase 2 | withdrawn | Dec 13, 2019 | Case Comprehensive Cancer Center | PI is leaving institution | Other (stated, no rule matched) |
| NCT00503581 | Megestrol in Treating Patients With Endometrial Neoplasia or Endometrial Hyperplasia | Phase 2 | terminated | Jul 19, 2007 | Gynecologic Oncology Group | not stated | Not stated |
| NCT03423082 | Pilot Study to Assess the Potential Clinical Utility of 18F Fluciclovine PET for Cervical… | Phase 4 | terminated | Feb 6, 2018 | Nghi Nguyen | Limited subject enrollment | Enrollment / accrual |
| NCT04567095 | A Study to Evaluate Awareness and Knowledge of the Fibristal Additional Risk Minimization… | — | withdrawn | Sep 28, 2020 | Allergan | This study was cancelled before any data collection due to business reasons. | Sponsor / business decision |
| NCT04567589 | A Study to Evaluate Awareness and Knowledge of the Fibristal Additional Risk Minimization… | — | withdrawn | Sep 28, 2020 | Allergan | This study was cancelled before any data collection due to business reasons. | Sponsor / business decision |
| NCT02425878 | Ulipristal Acetate 10 mg and Asisted Reproduction | Phase 3 | terminated | Apr 24, 2015 | Instituto Valenciano de Infertilidad, IVI VALENCIA | Lack of availibility of eligible subjects | Other (stated, no rule matched) |
| NCT02476955 | Open-label Phase 1b Study of ARQ 092 in Combination With Anastrozole | Phase 1 | terminated | Jun 22, 2015 | ArQule, Inc., a subsidiary of Merck Sharp & Dohme LLC, a subsidiary of Merck & Co., Inc. (Rahway, NJ USA) | not stated | Not stated |
| NCT01939028 | Lymph Node Mapping in Patients With Newly Diagnosed Endometrial Cancer Undergoing Surgery | N/A | terminated | Sep 11, 2013 | Case Comprehensive Cancer Center | Slow Accrual | Enrollment / accrual |
| NCT02045433 | Stereotactic Body Radiation Therapy (SABR) for Definitive Treatment of Locally Advanced… | Phase 2 | terminated | Jan 24, 2014 | University of Texas Southwestern Medical Center | The study was prematurely closed due to unacceptable toxicity. | Safety / toxicity |
| NCT01280045 | Influence of Aromatase Inhibitors and GnRH Analogs to Treat Uterine Leiomyoma by Vaginal… | N/A | terminated | Jan 20, 2011 | University of Sao Paulo | No grant was received then we stopped the recruitment | Enrollment / accrual |
| NCT01738724 | Study of the Efficacy of Dienogest in the Treatment of Uterine Leiomyomas When Compared… | Phase 4 | terminated | Nov 30, 2012 | University of Sao Paulo | PI went for a post-doc course and when he came back he moved for another job | Other (stated, no rule matched) |
| NCT03115593 | Compare the Performance of Targeted Biopsy Versus Aspiration Biopsy With a Pipette for… | N/A | withdrawn | Apr 14, 2017 | Brugmann University Hospital | Lack of human ressources | Other (stated, no rule matched) |
| NCT03583736 | Rapid First Contact Using Virtual Visits to Improve Time-To-Treatment for Uterine Cancer | N/A | withdrawn | Jul 11, 2018 | Case Comprehensive Cancer Center | PI decision | Other (stated, no rule matched) |
| NCT02317302 | FDG Tumor Heterogeneity During Chemoradiation as a Predictor of Response in Patients With… | Phase 1 | terminated | Dec 16, 2014 | Washington University School of Medicine | Insufficient funding | Funding |
| NCT03318107 | Ultrasound and Photoacoustic Imaging for Cervical Cancer | N/A | terminated | Oct 23, 2017 | Washington University School of Medicine | Low accrual | Enrollment / accrual |
| NCT01533207 | Gemcitabine Hydrochloride and Docetaxel Followed by Doxorubicin Hydrochloride or… | Phase 3 | terminated | Feb 15, 2012 | Gynecologic Oncology Group | not stated | Not stated |
| NCT04132349 | Ulipristal Acetate in Symptomatic Uterine Fibroid | Phase 4 | terminated | Oct 18, 2019 | Mỹ Đức Hospital | Ulipristal Acetate was recalled | Other (stated, no rule matched) |
| NCT01019278 | Proton Beam Radiation Therapy and Cisplatin in Treating Patients With Stage IB, Stage II,… | Phase 2 | withdrawn | Nov 24, 2009 | Abramson Cancer Center at Penn Medicine | not stated | Not stated |
| NCT03644459 | Safety and Efficacy of the Fully Humanized Anti - VEGF Monoclonal Antibody LYN00101 | Phase 1 | withdrawn | Aug 23, 2018 | Lynkcell Inc. | Unable to recruit individuals for the study | Enrollment / accrual |
| NCT02665962 | Evaluating the Effect of Perioperative Caloric Restriction Program on Perioperative… | N/A | terminated | Jan 28, 2016 | Abramson Cancer Center at Penn Medicine | Poor enrollment | Enrollment / accrual |
| NCT01392352 | HYPAZ: Hypertension Induced by Pazopanib(HYPAZ) | Phase 2 | terminated | Jul 12, 2011 | Cambridge University Hospitals NHS Foundation Trust | Following DMC review, due to slow recruitment of evaluable patients. | Enrollment / accrual |
| NCT03146039 | Non-Invasive Cervical Cancer Radiotherapy for Stage IB-IVB(NICER) | Phase 2 | withdrawn | May 9, 2017 | University of California, San Diego | Patient enrollment goal will not be met | Enrollment / accrual |
| NCT04125225 | What Are the Experiences of Patients With Pseudomyxoma Peritonei? | — | withdrawn | Oct 14, 2019 | University of Southampton | No participants enrolled. | Enrollment / accrual |
| NCT03466034 | The Role of Hypoxia as a Selective Pressure for TP53 Mutations | — | terminated | Mar 15, 2018 | Institute of Cancer Research, United Kingdom | Low numbers of eligible patients and failure to successfully recruit them. | Enrollment / accrual |
| NCT03699176 | Assessment of Safety and Efficacy of Vilaprisan in Subjects With Uterine Fibroids(ASTEROID 7) | Phase 3 | withdrawn | Oct 9, 2018 | Bayer | No patient was recruited, study withdrawn for feasibility reasons. | Enrollment / accrual |
| NCT03852979 | Neo-Adjuvant Chemotherapy and Conservative Surgery in Cervical Cancer to Preserve…(NEOCON-F) | Phase 2 | terminated | Feb 25, 2019 | The Netherlands Cancer Institute | study is merged with CONTESSA study | Other (stated, no rule matched) |
| NCT00394602 | Chemoradiation-Induced Nausea and Emesis: Quality of Life | — | terminated | Nov 1, 2006 | M.D. Anderson Cancer Center | Requested by PI during yearly Continuing Review | Other (stated, no rule matched) |
| NCT00519272 | A Prospective Study Examining the Barriers to Care for Harris County Cervical Cancer… | — | terminated | Aug 22, 2007 | M.D. Anderson Cancer Center | Requested by PI during yearly Continuing Review | Other (stated, no rule matched) |
| NCT00924066 | Ixabepilone to Treat Cervical Cancer | Phase 2 | terminated | Jun 18, 2009 | National Cancer Institute (NCI) | Premature closure due to slow/insufficient accrual. | Enrollment / accrual |
| NCT00204997 | Preservation of Ovarian Function Via LOT in Squamous Cell Carcinoma of the Cervix | N/A | terminated | Sep 20, 2005 | University of Wisconsin, Madison | slow accrual | Enrollment / accrual |
| NCT03795272 | Rucaparib Maintenance Therapy in Advanced Cervical Cancer(MaRuC) | Phase 2 | withdrawn | Jan 7, 2019 | Nordic Society of Gynaecological Oncology - Clinical Trials Unit | Lack of financial support | Funding |
| NCT01583686 | CAR T Cell Receptor Immunotherapy Targeting Mesothelin for Patients With Metastatic Cancer | Phase 1 / Phase 2 | terminated | Apr 24, 2012 | National Cancer Institute (NCI) | Study terminated due to slow/insufficient accrual. | Enrollment / accrual |
| NCT02566811 | Selective Targeting of Adjuvant Therapy for Endometrial Cancer (STATEC)(STATEC) | N/A | terminated | Oct 2, 2015 | University College, London | Withdrawal of funding by CR UK due to poor recruitment | Enrollment / accrual |
| NCT01834703 | Uterine Artery Embolization(UAE) Versus High-Intensity-Focused-Ultrasound(HIFU) for… | N/A | terminated | Apr 18, 2013 | Chinese University of Hong Kong | not stated | Not stated |
| NCT03210324 | A Study on the Mifepristone Tablets in the Treatment of Symptomatic Uterine Fibroids With… | Phase 4 | terminated | Jul 6, 2017 | China Resources Zizhu Pharmaceutical Co., Ltd. | It is difficult to recruit enough participants | Enrollment / accrual |
| NCT03613493 | Acceptability of Human Papillomavirus (HPV) Self-sampling Tools for Cervical Cancer… | N/A | terminated | Aug 3, 2018 | University of Miami | Budgetary and Timing Constraints | Funding |
| NCT00262821 | Cisplatin and Radiation Therapy With or Without Tirapazamine in Treating Patients With… | Phase 3 | terminated | Dec 7, 2005 | National Cancer Institute (NCI) | Study drug no longer available resulting in lack of study drug for participants. | Other (stated, no rule matched) |
| NCT02811159 | An Extension Study of 12 mg Proellex® (Telapristone Acetate) Administered Orally in the… | Phase 2 | terminated | Jun 23, 2016 | Repros Therapeutics Inc. | Business decision | Sponsor / business decision |
| NCT03836157 | Mirvetuximab Soravtansine (IMGN853) and Bevacizumab in Patients With Endometrial Cancer | Phase 2 | withdrawn | Feb 11, 2019 | University of Oklahoma | Study was not initiated. | Other (stated, no rule matched) |
| NCT02558348 | Phase 1/2a Evaluation of AL3818 in Subjects With Recurrent or Metastatic Endometrial,…(AL3818) | Phase 1 / Phase 2 | terminated | Sep 24, 2015 | Advenchen Laboratories, LLC | Sponsor termination | Other (stated, no rule matched) |
| NCT02153905 | T Cell Receptor Immunotherapy Targeting MAGE-A3 for Patients With Metastatic Cancer Who… | Phase 1 / Phase 2 | terminated | Jun 3, 2014 | National Cancer Institute (NCI) | Slow, insufficient accrual. | Enrollment / accrual |
| NCT01958112 | GSK1120212+GSK2141795 for Cervical Cancer | Phase 2 | terminated | Oct 8, 2013 | Dana-Farber Cancer Institute | Drug supply | Drug supply |
| NCT02907073 | Positron Emission Tomography (PET) Imaging Studies With NIS Reporter | Phase 1 / Phase 2 | terminated | Sep 20, 2016 | Mayo Clinic | pursuing IND | Other (stated, no rule matched) |
| NCT02879058 | Intraoperative Ultrasound in Laparoscopic or Robotic Myomectomy Patients | N/A | terminated | Aug 25, 2016 | The Cleveland Clinic | Due to inadequate enrollment. | Enrollment / accrual |
Stop reasons are registrant-reported free text and are displayed verbatim (truncated; hover for the full text). Categories come from explicit keyword rules and are never inferred from the study design, sponsor or outcome; a study that stopped for several reasons is filed under the first rule that matched. A TERMINATED status does not imply a negative result.
Data updated 23 days agoSource updated Apr 19, 2021source: clinicaltrials