Lymph Node Mapping in Patients With Newly Diagnosed Endometrial Cancer Undergoing Surgery

Inclusion Criteria:

* Women must have newly diagnosed histologically or cytologically confirmed endometrial cancer
* Women should have received no prior therapy for their disease
* Women who are planning to undergo hysterectomy, bilateral salpingo-oophorectomy, and pelvic lymphadenectomy for the management of their endometrial cancer
* Women must have the ability to understand and the willingness to sign a written informed consent document

Exclusion Criteria:

* Women who are receiving any other investigational agents
* Women with a history of allergic reactions attributed to compounds of similar chemical or biologic composition to isosulfan blue or indocyanine green or other agents used in this study
* Women with hypersensitivity to phenylmethane compounds, or a history of allergic reaction to iodides
* Patients with uncontrolled intercurrent illness including, but not limited to ongoing or active infection, symptomatic congestive heart failure, unstable angina pectoris, cardiac arrhythmia, or psychiatric illness/social situations that would limit compliance with study requirements
* Women with a history of prior loop electrosurgical excision procedure (LEEP) or cone procedures performed on their cervix
* Women with a history of lymphedema, lymphoma, or lymphatic hyperplasia (Castleman disease)
* Women with a history of a prior malignancy
* Women may also be excluded at the discretion of their surgeon if he or she feels that the patient is not an appropriate candidate