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Clinical trials · failure tracking
Oncology studies whose overall status is TERMINATED, WITHDRAWN or SUSPENDED on ClinicalTrials.gov, with the stop reason exactly as the registrant posted it. A category is attached only when an explicit keyword rule matches the text; CancerIndex never infers why a study stopped.
18 stopped studies mapped to Malignant Retinal Neoplasm and descendants · 89% state a reason
Over the 18 studies matching the cancer, status and year filters (the category filter does not change this chart). Each study is counted once, in the first matching category; greyed bars are studies whose text matched no rule or was empty.
Computedrules ci-stop-reasons-v1 · keyword matching only
A category is assigned when one of its keywords appears in the posted text (case-insensitive, whole words). Rules are tested in this order and the first match wins; every match is kept in the API (reasonMatches).
| NCT | Title | Phase | Status | First posted | Lead sponsor | Why stopped (as posted) | Category |
|---|---|---|---|---|---|---|---|
| NCT03016156 | Determination of the Sensitivity and Specificity of a Smartphone Application to Detect… | N/A | terminated | Jan 10, 2017 | St. Jude Children's Research Hospital | Accrual was slow. | Enrollment / accrual |
| NCT04344652 | Photoscreening for Retinoblastoma | N/A | withdrawn | Apr 14, 2020 | Phoenix Children's Hospital | Study administratively closed at IRB prior to enrollment. | Enrollment / accrual |
| NCT01987596 | Study of Fixed vs. Flexible Filgrastim to Accelerate Bone Marrow Recovery After… | Phase 3 | terminated | Nov 19, 2013 | Barbara Ann Karmanos Cancer Institute | not stated | Not stated |
| NCT01466855 | A Study of Intra-Ophthalmic Artery Topotecan Infusion for the Treatment of Retinoblastoma(IARB1) | Early Phase 1 | terminated | Nov 8, 2011 | Children's Hospital Medical Center, Cincinnati | Competing studies | Other (stated, no rule matched) |
| NCT02116959 | Alternating Systemic Chemotherapy and Intra-Arterial Melphalan (IAM) Chemotherapy in… | Phase 1 | terminated | Apr 17, 2014 | University of California, San Francisco | Low accrual | Enrollment / accrual |
| NCT01293539 | Intra-arterial Chemotherapy for the Treatment of Intraocular Retinoblastoma | Phase 2 | terminated | Feb 10, 2011 | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | IAC is now recognized as part of standard of care treatment options in the US. | Other (stated, no rule matched) |
| NCT02617862 | PCI Imaging System in Pediatric Ophthalmology | N/A | terminated | Dec 1, 2015 | Brenda Gallie | Proposed comparison (RetCam vs. COSMOS) was unfeasible. Device is now licensed in Canada. | Other (stated, no rule matched) |
| NCT00623077 | MT2004-30: Tomotherapy for Solid Tumors | Phase 1 | terminated | Feb 25, 2008 | Masonic Cancer Center, University of Minnesota | Replaced by another study | Other (stated, no rule matched) |
| NCT00003926 | Amifostine to Protect From Side Effects of PSCT in Treating Patients With Solid Tumors | Phase 1 | terminated | May 2, 2003 | Masonic Cancer Center, University of Minnesota | Withdrawn due to slow accrual | Enrollment / accrual |
| NCT01642823 | Cancer Biology of Retinoblastoma | — | terminated | Jul 17, 2012 | Stanford University | Logistics | Other (stated, no rule matched) |
| NCT00980551 | Pilot Study of Topotecan/Vincristine With Subconjunctival Carboplatin for Patients With…(RELRB1) | N/A | withdrawn | Sep 21, 2009 | Children's Hospital Medical Center, Cincinnati | No enrollment and competing studies | Enrollment / accrual |
| NCT01857752 | Phase II Study Temozolomide for Retinoblastoma Metastatic to the Central Nervous System… | Phase 2 | terminated | May 20, 2013 | Stanford University | accrual | Enrollment / accrual |
| NCT02655432 | Performance of a Photoscreener for Vision Screening in a Haitian Pediatric Population(POPH) | — | withdrawn | Jan 14, 2016 | Université de Montréal | waiting for ethic board approval | Other (stated, no rule matched) |
| NCT01393769 | Intra-arterial Chemotherapy With Melphalan for the Treatment of Retinoblastoma (RTB) in… | Phase 2 | terminated | Jul 13, 2011 | Hospital Sant Joan de Deu | Only 5 subjects could be enrolled. Sample of 25 pat. not be achieved (rare disease). | Enrollment / accrual |
| NCT00003273 | Chemotherapy Followed by Peripheral Stem Cell Transplantation in Treating Children With… | Phase 2 | withdrawn | Jan 27, 2003 | NYU Langone Health | not stated | Not stated |
| NCT01558960 | Intravitreal Injections of Melphalan for Retinoblastoma | N/A | terminated | Mar 20, 2012 | Hadassah Medical Organization | Sufficient findings to draw conclusions | Other (stated, no rule matched) |
| NCT00432445 | Proton Beam Radiation Therapy for Intraocular and Periocular Retinoblastoma | Phase 2 | terminated | Feb 7, 2007 | M.D. Anderson Cancer Center | Low accrual. | Enrollment / accrual |
| NCT01151748 | Intra-arterial Chemotherapy for Advanced Intraocular Retinoblastoma | Phase 2 | withdrawn | Jun 28, 2010 | Stanford University | Study abandoned; Could not obtain final SRC approval due to IND disagreements | Other (stated, no rule matched) |
Stop reasons are registrant-reported free text and are displayed verbatim (truncated; hover for the full text). Categories come from explicit keyword rules and are never inferred from the study design, sponsor or outcome; a study that stopped for several reasons is filed under the first rule that matched. A TERMINATED status does not imply a negative result.
Data updated 15 days agoSource updated Sep 15, 2026source: clinicaltrials