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Clinical trials · failure tracking
Oncology studies whose overall status is TERMINATED, WITHDRAWN or SUSPENDED on ClinicalTrials.gov, with the stop reason exactly as the registrant posted it. A category is attached only when an explicit keyword rule matches the text; CancerIndex never infers why a study stopped.
1,672 stopped studies mapped to Malignant Reproductive System Neoplasm and descendants · 89% state a reason
Over the 1,672 studies matching the cancer, status and year filters (the category filter does not change this chart). Each study is counted once, in the first matching category; greyed bars are studies whose text matched no rule or was empty.
Computedrules ci-stop-reasons-v1 · keyword matching only
A category is assigned when one of its keywords appears in the posted text (case-insensitive, whole words). Rules are tested in this order and the first match wins; every match is kept in the API (reasonMatches).
| NCT | Title | Phase | Status | First posted | Lead sponsor | Why stopped (as posted) | Category |
|---|---|---|---|---|---|---|---|
| NCT02749825 | Comparison of Trelstar Versus Lupron or Zoladex in Advanced Prostate Cancer | Phase 4 | terminated | Apr 25, 2016 | Pharmatech | Withdrawal of funding support | Funding |
| NCT01832831 | Anatomical and Functional Differences Between Continent and Incontinent Men Post Radical… | — | terminated | Apr 16, 2013 | University of Michigan | The study was completed as planned | Other (stated, no rule matched) |
| NCT00634894 | Femara (Letrozole) Versus Placebo for Patients With Ovarian, Fallopian Tube, or Primary… | Phase 2 | withdrawn | Mar 13, 2008 | M.D. Anderson Cancer Center | Study halted with no registration, the drug company sponsor withdrew support. | Sponsor / business decision |
| NCT00243646 | Implant and External Radiation for Prostate Cancer With or Without Hormonal Therapy: A… | Phase 3 | terminated | Oct 24, 2005 | Schiffler Cancer Center | poor accrual | Enrollment / accrual |
| NCT02479178 | A Study of BIND-014 in Patients With Urothelial Carcinoma, Cholangiocarcinoma, Cervical…(iNSITE2) | Phase 2 | terminated | Jun 24, 2015 | BIND Therapeutics | not stated | Not stated |
| NCT02110849 | Prostate Cancer Parameters for Patients Receiving Proton Treatment | — | withdrawn | Apr 10, 2014 | Indiana University | Closure of IU Health Proton Facility | Other (stated, no rule matched) |
| NCT00024167 | Chemotherapy With or Without Strontium-89 in Treating Patients With Prostate Cancer | Phase 3 | terminated | Jan 27, 2003 | M.D. Anderson Cancer Center | Terminated due to slow accrual | Enrollment / accrual |
| NCT01603420 | External Beam Radiation With or Without Chemotherapy to Treat High Risk Prostate Cancer | Phase 2 / Phase 3 | terminated | May 22, 2012 | Proton Collaborative Group | enrollment goals not met | Enrollment / accrual |
| NCT01675011 | Embozene Microspheres for Uterine Fibroid Embolization (UFE) | N/A | terminated | Aug 29, 2012 | Boston Scientific Corporation | Inadequate enrollment | Enrollment / accrual |
| NCT00526799 | Sorafenib + Topotecan for Platinum-Resistant Recurrent Ovarian Cancer | Phase 1 / Phase 2 | terminated | Sep 10, 2007 | Daniela Matei, MD | Study closed to accrual due unfavorable interim analysis | Efficacy / futility |
| NCT01220427 | Micro-RNA Expression Profiles in High Risk Prostate Cancer | — | terminated | Oct 13, 2010 | Wuerzburg University Hospital | not stated | Not stated |
| NCT00522301 | Sorafenib in Treating Patients With Ovarian Epithelial Cancer, Fallopian Tube Cancer, or… | Phase 2 | terminated | Aug 29, 2007 | Memorial Sloan Kettering Cancer Center | not stated | Not stated |
| NCT00122265 | Exploring Genomic, Proteomic and Dosimetric Determinants of Late Toxicity After Three… | — | terminated | Jul 22, 2005 | AHS Cancer Control Alberta | not stated | Not stated |
| NCT00523471 | Blood Test to Measure DNA Damage in Blood | — | terminated | Aug 31, 2007 | AHS Cancer Control Alberta | not stated | Not stated |
| NCT01514955 | An Initial Feasibility Study to Integrate MRI Based Brachytherapy and CT/MR Fused INRT in…(IMRT) | Phase 1 | withdrawn | Jan 23, 2012 | AHS Cancer Control Alberta | not stated | Not stated |
| NCT02014831 | Efficacy and Safety of Cetuximab in Metastatic Penile Carcinoma (PENILANE)(PENILANE) | Phase 2 | withdrawn | Dec 18, 2013 | Centre Leon Berard | Industry decline to supply study drug | Drug supply |
| NCT02470559 | Activated T-cell Therapy, Low-Dose Aldesleukin, and Sargramostim in Treating Patients… | Phase 1 | withdrawn | Jun 12, 2015 | Barbara Ann Karmanos Cancer Institute | Study did not accrue any participants, the PI has left the institution. | Enrollment / accrual |
| NCT02035124 | Cabazitaxel and BKM120 in Patients With Metastatic Castrate-Resistant Prostate Cancer… | Phase 2 | withdrawn | Jan 14, 2014 | SCRI Development Innovations, LLC | Study withdrawn due to slow accrual. No patients were enrolled. | Enrollment / accrual |
| NCT02130947 | Exercise Intervention for Pts With Metastatic Castration-Resistant Prostate Cancer… | N/A | withdrawn | May 6, 2014 | UNC Lineberger Comprehensive Cancer Center | We were not able to accrue any participants. | Enrollment / accrual |
| NCT02621684 | Physical Activity Intervention in African American Men After Radical Prostatectomy | N/A | withdrawn | Dec 3, 2015 | Washington University School of Medicine | Not able to enroll any participants due to disinterest | Enrollment / accrual |
| NCT02079155 | Robotic Athermal Nerve-Sparing Radical Prostatectomy | N/A | withdrawn | Mar 5, 2014 | Case Comprehensive Cancer Center | Research Cancelled | Other (stated, no rule matched) |
| NCT00250757 | Prostate Cancer Diagnosis Through NMR Spectroscopy of Semen and Prostatic Secretions | — | terminated | Nov 8, 2005 | New Mexico Cancer Research Alliance | Study was not renewed timely with IRB of record. | Other (stated, no rule matched) |
| NCT00734851 | Multimodality Phase II Study in Prostate Cancer | Phase 2 | terminated | Aug 14, 2008 | Duke University | Dose Limiting Toxicities | Safety / toxicity |
| NCT01624493 | BNC105P Combination Study in Partially Platinum Sensitive Ovarian Cancer Patients | Phase 1 / Phase 2 | withdrawn | Jun 20, 2012 | Hoosier Cancer Research Network | Phase I was conducted Australia. Phase II not conducted and no US pts enrolled. | Enrollment / accrual |
| NCT01840943 | A Study to Compare CAELYX With Topotecan HCL in Patients With Recurrent Epithelial… | Phase 3 | terminated | Apr 26, 2013 | Xian-Janssen Pharmaceutical Ltd. | the study was terminated due to medication supply issue from current manufacturer | Drug supply |
| NCT00932672 | Atkins Diet and Prostate Cancer Clinical Trial | Phase 2 | terminated | Jul 3, 2009 | Duke University | slow recruitment, lack of funding and PI transferred | Enrollment / accrual |
| NCT02139774 | Using Walk With Ease Walking Program With Men 65 and Older Being Treated for Prostate… | — | terminated | May 15, 2014 | UNC Lineberger Comprehensive Cancer Center | inadequate accrual | Enrollment / accrual |
| NCT00313612 | Oxaliplatin and Topotecan in Advance Ovarian Cancer | Phase 2 | terminated | Apr 12, 2006 | National Cancer Institute (NCI) | not stated | Not stated |
| NCT00596544 | Sexual Functioning After Primary Treatment of Ovarian Cancer | — | terminated | Jan 17, 2008 | Memorial Sloan Kettering Cancer Center | Lack of accrual | Enrollment / accrual |
| NCT01279785 | A Pilot Study of 123I-MIP-1072 SPECT/CT Imaging With Optional Compact Gamma Camera Probe… | — | withdrawn | Jan 19, 2011 | Molecular Insight Pharmaceuticals, Inc. | Similar study to be completd once kit for new formulation becomes available. | Other (stated, no rule matched) |
| NCT02396368 | A Study of Radium-223 in Combination With Tasquinimod in Bone-only Metastatic…(Radium-223) | Phase 1 | withdrawn | Mar 24, 2015 | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | Phase III study results for the drug Tesquinimod were not promising so it was a drug development… | Other (stated, no rule matched) |
| NCT02024685 | Treatment Decision Analysis Model for Prostate Cancer: A Randomized Trial | N/A | terminated | Dec 31, 2013 | Case Comprehensive Cancer Center | Funding unavailable | Funding |
| NCT02042885 | A Clinical Trial to Determine the Most Suitable Dose of OPB-111001 in Patients With… | Phase 1 / Phase 2 | terminated | Jan 23, 2014 | Otsuka Novel Products GmbH | not stated | Not stated |
| NCT00629330 | Dissemination of Prostate Cancer Screening to PCP's in African American Communities | Phase 4 | terminated | Mar 6, 2008 | Columbia University | Principal Investigator left the institution. | Investigator |
| NCT01175967 | Use of Palliative Performance and Symptom Distress Scales in Older Patients With Advanced… | — | terminated | Aug 5, 2010 | UNC Lineberger Comprehensive Cancer Center | Unable to meet accrual due to changing practice patters | Enrollment / accrual |
| NCT00093678 | Celecoxib in Managing Pain, Weight Loss, and Weakness in Patients With Advanced Cancer | N/A | withdrawn | Oct 8, 2004 | Eastern Cooperative Oncology Group | not stated | Not stated |
| NCT01530984 | Ipilimumab and GMCSF Immunotherapy for Prostate Cancer | Phase 2 | withdrawn | Feb 10, 2012 | Lawrence Fong | Unable to execute contract | Other (stated, no rule matched) |
| NCT00585416 | Study of CGC-11047 in Patients With Metastatic Hormone Refractory Prostate Cancer | Phase 2 | terminated | Jan 3, 2008 | University of Wisconsin, Madison | Further evaluation of phase I dosing | Other (stated, no rule matched) |
| NCT00288106 | S0437 Long-Term Follow-Up of Patients Who Were Diagnosed With Prostate Cancer on PCPT | — | terminated | Feb 7, 2006 | SWOG Cancer Research Network | Poor accrual resulted in lack of feasibility to evaluate endpoints. | Enrollment / accrual |
| NCT00758732 | Docetaxel/Carboplatin Versus Docetaxel/Caelyx in Pretreated Patients With Ovarian… | Phase 2 | terminated | Sep 25, 2008 | Hellenic Oncology Research Group | Poor accrual | Enrollment / accrual |
| NCT01745718 | Clinical Study Evaluating Targeted Biopsies and Cytological Imprints in Prostate Cancer | N/A | withdrawn | Dec 10, 2012 | Oslo University Hospital | The study was stopped for technical reasons | Other (stated, no rule matched) |
| NCT02185170 | DEPORRA-CoProst: Assessment of New Fluorescence Imagery Techniques Using Prostate Chips… | N/A | terminated | Jul 9, 2014 | University Hospital, Grenoble | Results of 5 first patients show that chips' cauterization interferes the signal | Other (stated, no rule matched) |
| NCT02480010 | A Study of Pertuzumab in Participants With Prostate Cancer | Phase 2 | terminated | Jun 24, 2015 | Hoffmann-La Roche | The study was terminated at the time of interim analysis since none of the participants showed a… | Efficacy / futility |
| NCT00215631 | Can Tadalafil Maintain Erectile Function In Patients Treated With Radiotherapy For… | Phase 3 | terminated | Sep 22, 2005 | Erasmus Medical Center | slow recruitment | Enrollment / accrual |
| NCT01368003 | STA-9090 in Castration-Resistant Prostate Cancer With Assessment of Androgen Receptor… | Phase 2 | withdrawn | Jun 7, 2011 | Toni Choueiri, MD | Loss of funding. | Funding |
| NCT01296035 | Panitumumab and Gemcitabine in Relapsed Ovarian Cancer(PanGem) | Phase 2 | terminated | Feb 15, 2011 | Women and Infants Hospital of Rhode Island | Newer technologies available; poor accrual to study. | Enrollment / accrual |
| NCT02109224 | Ibrutinib in Treating Relapsed or Refractory B-Cell Non-Hodgkin Lymphoma in Patients With… | Phase 1 | terminated | Apr 9, 2014 | National Cancer Institute (NCI) | Inadequate accrual rate | Enrollment / accrual |
| NCT00471120 | Feasibility Study: Accuracy of Biomarker in Detection of Endometrial Cancer | N/A | terminated | May 9, 2007 | Dick Domanik | Study terminated due to protocol deficiencies. | Other (stated, no rule matched) |
| NCT02022904 | Prostate Cancer Circulating Tumor Cells Based on Epithelial-Mesenchymal Transition Biology | N/A | withdrawn | Dec 30, 2013 | Duke University | not stated | Not stated |
| NCT01744821 | Vitamin D for Women at Increased Risk of Developing Ovarian, Fallopian, or Primary… | N/A | terminated | Dec 7, 2012 | Northwestern University | Inability to recruit study subjects | Enrollment / accrual |
Stop reasons are registrant-reported free text and are displayed verbatim (truncated; hover for the full text). Categories come from explicit keyword rules and are never inferred from the study design, sponsor or outcome; a study that stopped for several reasons is filed under the first rule that matched. A TERMINATED status does not imply a negative result.
Data updated 23 days agoSource updated Apr 25, 2016source: clinicaltrials