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Clinical trials · failure tracking
Oncology studies whose overall status is TERMINATED, WITHDRAWN or SUSPENDED on ClinicalTrials.gov, with the stop reason exactly as the registrant posted it. A category is attached only when an explicit keyword rule matches the text; CancerIndex never infers why a study stopped.
840 stopped studies mapped to Malignant Prostate Neoplasm and descendants · 92% state a reason
Over the 840 studies matching the cancer, status and year filters (the category filter does not change this chart). Each study is counted once, in the first matching category; greyed bars are studies whose text matched no rule or was empty.
Computedrules ci-stop-reasons-v1 · keyword matching only
A category is assigned when one of its keywords appears in the posted text (case-insensitive, whole words). Rules are tested in this order and the first match wins; every match is kept in the API (reasonMatches).
| NCT | Title | Phase | Status | First posted | Lead sponsor | Why stopped (as posted) | Category |
|---|---|---|---|---|---|---|---|
| NCT00664196 | Trial of Anti-PSMA Designer T Cells in Advanced Prostate Cancer After Non-Myeloablative… | Phase 1 | suspended | Apr 22, 2008 | Roger Williams Medical Center | Funding | Funding |
| NCT02140138 | An Open Label Randomised Trial of RNActive® Cancer Vaccine in High Risk and Intermediate… | Phase 2 | terminated | May 16, 2014 | CureVac | Recruitment was terminated after enrolment of 35 instead of 36 evaluable patients for… | Enrollment / accrual |
| NCT01658527 | TAK-700 in Castration Resistant Prostate Cancer | Phase 2 | withdrawn | Aug 7, 2012 | European Organisation for Research and Treatment of Cancer - EORTC | Pharmaceutical company has terminated orteronel (TAK-700) development for Prostate Cancer | Sponsor / business decision |
| NCT00503984 | A Phase I/II Study of Azacitidine, Docetaxel, and Prednisone for Metastatic Prostate… | Phase 1 / Phase 2 | terminated | Jul 19, 2007 | University of Miami | Withdrawal of Funding | Funding |
| NCT00216060 | Risedronate to Prevent Skeletal Related Events in Patients With Metastatic Prostate… | Phase 3 | terminated | Sep 22, 2005 | Christopher Sweeney, MBBS | Terminated due to low accrual | Enrollment / accrual |
| NCT01173146 | Imaging of Residual Tumor During Prostatectomy | — | withdrawn | Jul 30, 2010 | Spectros Corporation | Costs for antibody production rose; supplemental funding request not approved. | Funding |
| NCT00985738 | Role of Dutasteride in Patients Undergoing 3D Mapping Biopsy in Early Stage Prostate… | Phase 2 | terminated | Sep 28, 2009 | University of Colorado, Denver | Low recruitment | Enrollment / accrual |
| NCT00801996 | Epidemiologic, Clinical and Genetic Profile of Prostate Cancer in Arab Countries(ProstateCA) | — | withdrawn | Dec 4, 2008 | Weill Medical College of Cornell University | Closed by Investigator | Investigator |
| NCT01981707 | F-choline PET in Early Response Assessment for Castration Resistant Prostatic Cancer(PRECHOL) | Phase 2 / Phase 3 | terminated | Nov 11, 2013 | University Hospital, Grenoble | enrollment default | Enrollment / accrual |
| NCT02512120 | Volume Controlled Ventilation vs Autoflow-volume Controlled Ventilation(VCVAFVCV) | N/A | withdrawn | Jul 30, 2015 | Korea University Anam Hospital | The backgroud of this study was not well discussed. | Other (stated, no rule matched) |
| NCT02749825 | Comparison of Trelstar Versus Lupron or Zoladex in Advanced Prostate Cancer | Phase 4 | terminated | Apr 25, 2016 | Pharmatech | Withdrawal of funding support | Funding |
| NCT01832831 | Anatomical and Functional Differences Between Continent and Incontinent Men Post Radical… | — | terminated | Apr 16, 2013 | University of Michigan | The study was completed as planned | Other (stated, no rule matched) |
| NCT00243646 | Implant and External Radiation for Prostate Cancer With or Without Hormonal Therapy: A… | Phase 3 | terminated | Oct 24, 2005 | Schiffler Cancer Center | poor accrual | Enrollment / accrual |
| NCT02110849 | Prostate Cancer Parameters for Patients Receiving Proton Treatment | — | withdrawn | Apr 10, 2014 | Indiana University | Closure of IU Health Proton Facility | Other (stated, no rule matched) |
| NCT00024167 | Chemotherapy With or Without Strontium-89 in Treating Patients With Prostate Cancer | Phase 3 | terminated | Jan 27, 2003 | M.D. Anderson Cancer Center | Terminated due to slow accrual | Enrollment / accrual |
| NCT01603420 | External Beam Radiation With or Without Chemotherapy to Treat High Risk Prostate Cancer | Phase 2 / Phase 3 | terminated | May 22, 2012 | Proton Collaborative Group | enrollment goals not met | Enrollment / accrual |
| NCT01220427 | Micro-RNA Expression Profiles in High Risk Prostate Cancer | — | terminated | Oct 13, 2010 | Wuerzburg University Hospital | not stated | Not stated |
| NCT00122265 | Exploring Genomic, Proteomic and Dosimetric Determinants of Late Toxicity After Three… | — | terminated | Jul 22, 2005 | AHS Cancer Control Alberta | not stated | Not stated |
| NCT00523471 | Blood Test to Measure DNA Damage in Blood | — | terminated | Aug 31, 2007 | AHS Cancer Control Alberta | not stated | Not stated |
| NCT02035124 | Cabazitaxel and BKM120 in Patients With Metastatic Castrate-Resistant Prostate Cancer… | Phase 2 | withdrawn | Jan 14, 2014 | SCRI Development Innovations, LLC | Study withdrawn due to slow accrual. No patients were enrolled. | Enrollment / accrual |
| NCT02130947 | Exercise Intervention for Pts With Metastatic Castration-Resistant Prostate Cancer… | N/A | withdrawn | May 6, 2014 | UNC Lineberger Comprehensive Cancer Center | We were not able to accrue any participants. | Enrollment / accrual |
| NCT02621684 | Physical Activity Intervention in African American Men After Radical Prostatectomy | N/A | withdrawn | Dec 3, 2015 | Washington University School of Medicine | Not able to enroll any participants due to disinterest | Enrollment / accrual |
| NCT02079155 | Robotic Athermal Nerve-Sparing Radical Prostatectomy | N/A | withdrawn | Mar 5, 2014 | Case Comprehensive Cancer Center | Research Cancelled | Other (stated, no rule matched) |
| NCT00250757 | Prostate Cancer Diagnosis Through NMR Spectroscopy of Semen and Prostatic Secretions | — | terminated | Nov 8, 2005 | New Mexico Cancer Research Alliance | Study was not renewed timely with IRB of record. | Other (stated, no rule matched) |
| NCT00734851 | Multimodality Phase II Study in Prostate Cancer | Phase 2 | terminated | Aug 14, 2008 | Duke University | Dose Limiting Toxicities | Safety / toxicity |
| NCT00932672 | Atkins Diet and Prostate Cancer Clinical Trial | Phase 2 | terminated | Jul 3, 2009 | Duke University | slow recruitment, lack of funding and PI transferred | Enrollment / accrual |
| NCT02139774 | Using Walk With Ease Walking Program With Men 65 and Older Being Treated for Prostate… | — | terminated | May 15, 2014 | UNC Lineberger Comprehensive Cancer Center | inadequate accrual | Enrollment / accrual |
| NCT01279785 | A Pilot Study of 123I-MIP-1072 SPECT/CT Imaging With Optional Compact Gamma Camera Probe… | — | withdrawn | Jan 19, 2011 | Molecular Insight Pharmaceuticals, Inc. | Similar study to be completd once kit for new formulation becomes available. | Other (stated, no rule matched) |
| NCT02396368 | A Study of Radium-223 in Combination With Tasquinimod in Bone-only Metastatic…(Radium-223) | Phase 1 | withdrawn | Mar 24, 2015 | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | Phase III study results for the drug Tesquinimod were not promising so it was a drug development… | Other (stated, no rule matched) |
| NCT02024685 | Treatment Decision Analysis Model for Prostate Cancer: A Randomized Trial | N/A | terminated | Dec 31, 2013 | Case Comprehensive Cancer Center | Funding unavailable | Funding |
| NCT02042885 | A Clinical Trial to Determine the Most Suitable Dose of OPB-111001 in Patients With… | Phase 1 / Phase 2 | terminated | Jan 23, 2014 | Otsuka Novel Products GmbH | not stated | Not stated |
| NCT00629330 | Dissemination of Prostate Cancer Screening to PCP's in African American Communities | Phase 4 | terminated | Mar 6, 2008 | Columbia University | Principal Investigator left the institution. | Investigator |
| NCT01530984 | Ipilimumab and GMCSF Immunotherapy for Prostate Cancer | Phase 2 | withdrawn | Feb 10, 2012 | Lawrence Fong | Unable to execute contract | Other (stated, no rule matched) |
| NCT00585416 | Study of CGC-11047 in Patients With Metastatic Hormone Refractory Prostate Cancer | Phase 2 | terminated | Jan 3, 2008 | University of Wisconsin, Madison | Further evaluation of phase I dosing | Other (stated, no rule matched) |
| NCT00288106 | S0437 Long-Term Follow-Up of Patients Who Were Diagnosed With Prostate Cancer on PCPT | — | terminated | Feb 7, 2006 | SWOG Cancer Research Network | Poor accrual resulted in lack of feasibility to evaluate endpoints. | Enrollment / accrual |
| NCT01745718 | Clinical Study Evaluating Targeted Biopsies and Cytological Imprints in Prostate Cancer | N/A | withdrawn | Dec 10, 2012 | Oslo University Hospital | The study was stopped for technical reasons | Other (stated, no rule matched) |
| NCT02185170 | DEPORRA-CoProst: Assessment of New Fluorescence Imagery Techniques Using Prostate Chips… | N/A | terminated | Jul 9, 2014 | University Hospital, Grenoble | Results of 5 first patients show that chips' cauterization interferes the signal | Other (stated, no rule matched) |
| NCT02480010 | A Study of Pertuzumab in Participants With Prostate Cancer | Phase 2 | terminated | Jun 24, 2015 | Hoffmann-La Roche | The study was terminated at the time of interim analysis since none of the participants showed a… | Efficacy / futility |
| NCT00215631 | Can Tadalafil Maintain Erectile Function In Patients Treated With Radiotherapy For… | Phase 3 | terminated | Sep 22, 2005 | Erasmus Medical Center | slow recruitment | Enrollment / accrual |
| NCT01368003 | STA-9090 in Castration-Resistant Prostate Cancer With Assessment of Androgen Receptor… | Phase 2 | withdrawn | Jun 7, 2011 | Toni Choueiri, MD | Loss of funding. | Funding |
| NCT02022904 | Prostate Cancer Circulating Tumor Cells Based on Epithelial-Mesenchymal Transition Biology | N/A | withdrawn | Dec 30, 2013 | Duke University | not stated | Not stated |
| NCT01561482 | Study of Metformin With Simvastatin for Men With Prostate Carcinoma | Phase 2 | withdrawn | Mar 23, 2012 | Nicholas Mitsiades | Study closed due to slow/low enrollment; no subjects were enrolled. | Enrollment / accrual |
| NCT00809458 | Biomarker Study of Neoadjuvant Vitamin E in Patients With Locally Treatable Prostate… | Phase 3 | terminated | Dec 17, 2008 | New Mexico Cancer Research Alliance | Low rate of accrual. | Enrollment / accrual |
| NCT00581113 | Neural Stem Cell Preserving Brain Radiation Therapy & Stereotactic Radiosurgery in… | Phase 3 | terminated | Dec 27, 2007 | Virginia Commonwealth University | New research priorities | Other (stated, no rule matched) |
| NCT01705652 | Study to Assess the Activity of Nexrutine® in Prostate Cancer Patients(Nexrutine) | Phase 2 | terminated | Oct 12, 2012 | The University of Texas Health Science Center at San Antonio | loss of funding | Funding |
| NCT00921258 | Active Control of Prostatic Cancer With Criteria of Latence(SURACAP) | — | terminated | Jun 16, 2009 | Clinique Mutualiste Chirurgicale de la Loire | Financial problem (not enough budget to continue the study) | Funding |
| NCT01242748 | A Degarelix Trial in Patients With Prostate Cancer | Phase 3 | terminated | Nov 17, 2010 | Ferring Pharmaceuticals | Inadequate recruitment resulting in a too low patient number for collection of long term efficacy… | Efficacy / futility |
| NCT01520441 | BOTOX in Men With Prostate Cancer With Lower Urinary Tract Symptoms(LUTS)/Benign… | Early Phase 1 | withdrawn | Jan 30, 2012 | The University of Texas Health Science Center, Houston | not stated | Not stated |
| NCT02424513 | A Study of Positron Emission Tomography (PET) With [89]Zr-Df-IAb2M in Patients With… | Phase 2 | withdrawn | Apr 23, 2015 | ImaginAb, Inc. | Clinical trial was postponed as a result of restructured business priorities. | Sponsor / business decision |
| NCT00118066 | Calcitriol in Preventing Prostate Cancer in Patients With Prostatic Intraepithelial… | Phase 2 | terminated | Jul 11, 2005 | Rutgers, The State University of New Jersey | Slow accruaL, lack of scientific progress | Enrollment / accrual |
Stop reasons are registrant-reported free text and are displayed verbatim (truncated; hover for the full text). Categories come from explicit keyword rules and are never inferred from the study design, sponsor or outcome; a study that stopped for several reasons is filed under the first rule that matched. A TERMINATED status does not imply a negative result.
Data updated 23 days agoSource updated Jun 17, 2016source: clinicaltrials