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Clinical trials · failure tracking
Oncology studies whose overall status is TERMINATED, WITHDRAWN or SUSPENDED on ClinicalTrials.gov, with the stop reason exactly as the registrant posted it. A category is attached only when an explicit keyword rule matches the text; CancerIndex never infers why a study stopped.
840 stopped studies mapped to Malignant Prostate Neoplasm and descendants · 92% state a reason
Over the 840 studies matching the cancer, status and year filters (the category filter does not change this chart). Each study is counted once, in the first matching category; greyed bars are studies whose text matched no rule or was empty.
Computedrules ci-stop-reasons-v1 · keyword matching only
A category is assigned when one of its keywords appears in the posted text (case-insensitive, whole words). Rules are tested in this order and the first match wins; every match is kept in the API (reasonMatches).
| NCT | Title | Phase | Status | First posted | Lead sponsor | Why stopped (as posted) | Category |
|---|---|---|---|---|---|---|---|
| NCT00084864 | Calcitriol and Dexamethasone Before Radical Prostatectomy in Treating Patients With… | Phase 2 | terminated | Jun 11, 2004 | Roswell Park Cancer Institute | sample size is too small to draw a conclusion | Other (stated, no rule matched) |
| NCT01558492 | Carboplatin and Paclitaxel in Patients With Metastatic, Castrate-Resistant Prostate Cancer | Phase 2 | terminated | Mar 20, 2012 | Weill Medical College of Cornell University | Poor accrual | Enrollment / accrual |
| NCT01338012 | Sipuleucel-T in Metastatic Castrate Resistant Prostate Cancer(mCRPC) | Phase 2 | terminated | Apr 19, 2011 | Dendreon | Administrative reasons. | Other (stated, no rule matched) |
| NCT01642732 | Study of Everolimus Added to Combined Hormonal and Radiation Therapy for High Risk… | Phase 1 | terminated | Jul 17, 2012 | University of Michigan Rogel Cancer Center | Lack of accrual and funding expires in June, 2014. | Enrollment / accrual |
| NCT02429804 | NaF/FDG PET/MRI in Measuring Response to Radium Ra 223 Dichloride in Patients With… | Phase 1 | terminated | Apr 29, 2015 | Stanford University | Accrual factor | Enrollment / accrual |
| NCT01385293 | BKM120 in Metastatic Castration-resistant Prostate Cancer | Phase 2 | terminated | Jun 30, 2011 | Andrew J. Armstrong, MD | The trial was stopped at the first stage due to futility | Efficacy / futility |
| NCT01940237 | A Pilot Trial of Interpersonal Psychotherapy for the Treatment of Depression in Patients… | N/A | terminated | Sep 12, 2013 | New York State Psychiatric Institute | Low recruitment | Enrollment / accrual |
| NCT01215032 | Metformin in Castration-Resistant Prostate Cancer | Phase 2 | terminated | Oct 5, 2010 | Massachusetts General Hospital | slow accrual, competing clinical trials | Enrollment / accrual |
| NCT01735396 | Abiraterone Acetate Trial in African American Prostate Cancer Patients | Phase 2 | terminated | Nov 28, 2012 | Icahn School of Medicine at Mount Sinai | poor accrual | Enrollment / accrual |
| NCT01828476 | Navitoclax and Abiraterone Acetate With or Without Hydroxychloroquine in Treating… | Phase 2 | terminated | Apr 10, 2013 | Rutgers, The State University of New Jersey | The Investigator left the organization. | Investigator |
| NCT00244894 | Acupuncture in Treating Hot Flashes in Patients With Prostate Cancer | N/A | terminated | Oct 27, 2005 | OHSU Knight Cancer Institute | not stated | Not stated |
| NCT00459810 | Paclitaxel Poliglumex and Estradiol in Treating Patients With Stage IV Prostate Cancer | Phase 2 | terminated | Apr 13, 2007 | OHSU Knight Cancer Institute | not stated | Not stated |
| NCT00482274 | Docetaxel in Treating Patients With Relapsed Prostate Cancer | Phase 2 | terminated | Jun 5, 2007 | OHSU Knight Cancer Institute | Drug supplier stopped funding due to loss of study drug (docetaxel) patent. | Funding |
| NCT01913015 | Dietary Fat Levels and Abiraterone Acetate Uptake in Patients With Metastatic… | Phase 1 | terminated | Jul 31, 2013 | OHSU Knight Cancer Institute | After enrollment of the first 3 subjects, an interim assessment was conducted. Comparing DBS… | Enrollment / accrual |
| NCT02840162 | Pre-Prostatectomy Celecoxib or Placebo | Phase 2 | terminated | Jul 21, 2016 | OHSU Knight Cancer Institute | Drug safety concerns | Safety / toxicity |
| NCT00937417 | S0716 Vandetanib and Docetaxel in Treating Patients With Advanced Solid Tumors | Phase 1 | withdrawn | Jul 13, 2009 | SWOG Cancer Research Network | Withdrawn because SWOG no longer pursuing this study at this time | Other (stated, no rule matched) |
| NCT02247960 | Antibiotic Prophylaxis for Urinary Catheter Removal After Radical Prostatectomy(Abx) | N/A | terminated | Sep 25, 2014 | University of Rochester | Interim analysis determined that the study should be concluded for futility. | Efficacy / futility |
| NCT02370355 | Molecular Characterization of CTCs and ctDNA in Blood and Plasma Samples From Patients… | — | terminated | Feb 24, 2015 | University of Southern California | Sponsor decided not to pursue study | Sponsor / business decision |
| NCT01450683 | Study of Itraconazole in Castrate-resistant Prostate Cancer (CRPC) Post-chemotherapy | Phase 2 | terminated | Oct 12, 2011 | Stanford University | Low accrual | Enrollment / accrual |
| NCT02656615 | Abiraterone-Rechallenge Study for CRPC Patients(ABI-RE) | Phase 2 | terminated | Jan 15, 2016 | Aurelius Omlin | Lack of Patient accrual | Enrollment / accrual |
| NCT02483884 | PET/CT Imaging Study of the Safety and Diagnostic Performance of [68Ga]RM2 in Patients… | Phase 1 / Phase 2 | terminated | Jun 29, 2015 | Lantheus Biosciences Ltd. | Business decision | Sponsor / business decision |
| NCT01155791 | Phase I Sodium Selenite in Combination With Docetaxel in Castration-resistant Prostate… | Phase 1 | terminated | Jul 2, 2010 | Sandy Srinivas | not stated | Not stated |
| NCT01933022 | A Study in Patients With Metastatic Prostate Cancer to Assess How the Drug Eligard®,…(EFFECT) | Phase 4 | terminated | Aug 30, 2013 | Astellas Pharma Europe Ltd. | Termination due to high current screen rate failure and unreliable PSA mRNA assay. | Other (stated, no rule matched) |
| NCT01087580 | Docetaxel + Prednisone With or Without Radiation for Castrate Resistant Prostate Cancer | Phase 2 | withdrawn | Mar 16, 2010 | Northwestern University | not stated | Not stated |
| NCT01817738 | Trial of RNActive®-Derived Prostate Cancer Vaccine in Metastatic Castrate-refractory… | Phase 1 / Phase 2 | terminated | Mar 25, 2013 | CureVac | Follow up period after primary analysis was prematurely stopped because more mature data will not… | Other (stated, no rule matched) |
| NCT00823771 | A Pilot Study to Assess the Follow-up of Prostate Cancer Patients Who Have Undergone…(PROFUGO) | — | terminated | Jan 16, 2009 | Barwon Health | Data review showed that the study was underpowered to draw clear conlcusions | Other (stated, no rule matched) |
| NCT02421575 | Hydroxychloroquine in Blocking Autophagy in Patients With Prostate Cancer Undergoing… | Early Phase 1 | terminated | Apr 20, 2015 | Rutgers, The State University of New Jersey | slow accrual | Enrollment / accrual |
| NCT00879619 | Taxotere/Prednisone Plus Sunitinib in Chemotherapy-Naïve, Hormone Refractory Prostate… | Phase 1 / Phase 2 | terminated | Apr 10, 2009 | John P. Fruehauf | Terminated due to slow accrual. | Enrollment / accrual |
| NCT01762956 | Pelvic Floor Muscles Training in Men Undergoing Radiotherapy for Prostate Cancer:… | N/A | terminated | Jan 8, 2013 | University of Sao Paulo | Unobtainable sample size | Other (stated, no rule matched) |
| NCT01699672 | Group-based or Individual Information About Disease and Treatment Plan | N/A | terminated | Oct 4, 2012 | Norwegian University of Science and Technology | Problems recruiting patients (not willing, travel time, no respons) | Enrollment / accrual |
| NCT01748110 | Health Interventions in Men Undergoing Radical Prostatectomy(HIM-UP) | N/A | withdrawn | Dec 12, 2012 | Johns Hopkins University | Funding could not be secured | Funding |
| NCT01913197 | Using Magnetic Resonance Imaging (MRI) to Guide Differential-Dose Prostate Brachytherapy | Phase 1 / Phase 2 | terminated | Jul 31, 2013 | St. Luke's-Roosevelt Hospital Center | low enrollment | Enrollment / accrual |
| NCT00686036 | Trial Assessing Zactima Against Placebo in Prostate Cancer Subjects Undergoing…(ZENITH) | Phase 2 | terminated | May 29, 2008 | Genzyme, a Sanofi Company | Slow recruitment | Enrollment / accrual |
| NCT00598858 | Neoadjuvant Docetaxel on Newly Diagnosed Intermediate and High Grade Cancer of the…(2007-5904) | Phase 2 | withdrawn | Jan 23, 2008 | John P. Fruehauf | Halted due to zero accrual and lack of funding | Enrollment / accrual |
| NCT00565227 | Phase I Study of Vorinostat in Combination With Docetaxel in Patients With Advanced and… | Phase 1 | terminated | Nov 29, 2007 | University of Michigan Rogel Cancer Center | closed due to toxicity | Safety / toxicity |
| NCT02404428 | Utilizing MRI to Study the Effect of Sulforaphane on Prostate Cancer(ESCAPE-ING) | N/A | terminated | Mar 31, 2015 | Quadram Institute Bioscience | Problems with recruitment | Enrollment / accrual |
| NCT02645591 | Randomized AmnioFix Study During Radical Prostatectomy | Phase 2 | withdrawn | Jan 1, 2016 | M.D. Anderson Cancer Center | not stated | Not stated |
| NCT00767845 | Symptom Management in African-American Men With Localized Prostate Cancer | — | withdrawn | Oct 7, 2008 | Baylor College of Medicine | No subjects were enrolled here or at UCSF. | Enrollment / accrual |
| NCT00933426 | Lenalidomide and Paclitaxel in Prostate Cancer | Phase 1 | terminated | Jul 7, 2009 | M.D. Anderson Cancer Center | Terminated early due to slow accrual as Phase I dose escalation study. | Enrollment / accrual |
| NCT01705405 | Merging of Endoscopic and Ultrasound Images for Laparoscopic Surgery(FEE) | N/A | terminated | Oct 12, 2012 | AdministrateurCIC | due to a problem of device | Other (stated, no rule matched) |
| NCT01761812 | Multiparametric MRI for Prostate Cancer Localization and Characterization: New Methods | N/A | terminated | Jan 7, 2013 | Sunnybrook Health Sciences Centre | Inadequate accrual | Enrollment / accrual |
| NCT02656563 | Radium 223 Following Intermittent ADT(RAND) | Phase 2 | withdrawn | Jan 15, 2016 | Canadian Urology Research Consortium | not stated | Not stated |
| NCT02169063 | Carbon-11 Acetate and Fluorine F 18 Sodium Fluoride PET as a Biomarker of Treatment… | N/A | withdrawn | Jun 20, 2014 | University of Washington | not stated | Not stated |
| NCT00691899 | A Study to Assess the Effects of MK0822 in Prolonging Time to First Bone Metastasis in… | Phase 3 | withdrawn | Jun 6, 2008 | Merck Sharp & Dohme LLC | Withdrawn for administrative reasons | Other (stated, no rule matched) |
| NCT01379378 | Male Stress Urinary Incontinence and Sexual Health | — | withdrawn | Jun 23, 2011 | Stanford University | not stated | Not stated |
| NCT02678520 | Clinical Trial Comparing 3-D RT vs. IMRT in Post- Prostatectomy Prostate Cancer Patients | Phase 2 | withdrawn | Feb 9, 2016 | University of Kansas Medical Center | PI no longer at institution. Study terminated prior to enrolling subjects. | Enrollment / accrual |
| NCT00003858 | Mitoxantrone Following Surgery in Treating Patients With Prostate Cancer at High Risk for… | Phase 2 | withdrawn | Sep 14, 2004 | Alliance for Clinical Trials in Oncology | The study was not activated. | Other (stated, no rule matched) |
| NCT01481441 | Quantification of Contrast Enhanced Ultrasound (CEUS) in the Detection of Prostate Cancer(AMC_2011_190) | N/A | terminated | Nov 29, 2011 | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | New study protocol started including targeted biopsies | Other (stated, no rule matched) |
| NCT00861471 | Docetaxel (Taxotere) and Imatinib Mesylate (Gleevec) in Hormone Refractory Prostate Cancer | Phase 1 / Phase 2 | terminated | Mar 13, 2009 | NYU Langone Health | due to slow accrual | Enrollment / accrual |
| NCT00003682 | Methylprednisolone With or Without Doxorubicin in Treating Patients With Metastatic… | Phase 3 | terminated | Jan 27, 2004 | UNICANCER | lack of inclusions | Other (stated, no rule matched) |
Stop reasons are registrant-reported free text and are displayed verbatim (truncated; hover for the full text). Categories come from explicit keyword rules and are never inferred from the study design, sponsor or outcome; a study that stopped for several reasons is filed under the first rule that matched. A TERMINATED status does not imply a negative result.
Data updated 23 days agoSource updated Jun 12, 2017source: clinicaltrials