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Clinical trials · failure tracking
Oncology studies whose overall status is TERMINATED, WITHDRAWN or SUSPENDED on ClinicalTrials.gov, with the stop reason exactly as the registrant posted it. A category is attached only when an explicit keyword rule matches the text; CancerIndex never infers why a study stopped.
840 stopped studies mapped to Malignant Prostate Neoplasm and descendants · 92% state a reason
Over the 840 studies matching the cancer, status and year filters (the category filter does not change this chart). Each study is counted once, in the first matching category; greyed bars are studies whose text matched no rule or was empty.
Computedrules ci-stop-reasons-v1 · keyword matching only
A category is assigned when one of its keywords appears in the posted text (case-insensitive, whole words). Rules are tested in this order and the first match wins; every match is kept in the API (reasonMatches).
| NCT | Title | Phase | Status | First posted | Lead sponsor | Why stopped (as posted) | Category |
|---|---|---|---|---|---|---|---|
| NCT01996852 | Improving Erectile Function and Quality of Life After Prostate Cancer Treatment | N/A | terminated | Nov 27, 2013 | Case Comprehensive Cancer Center | Premature terminated at institution request | Other (stated, no rule matched) |
| NCT02121600 | 18F-FCH PET/MRI to Assess Tumor Response in Castration Resistant Prostate Cancer | N/A | terminated | Apr 23, 2014 | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | Low accrual | Enrollment / accrual |
| NCT02911922 | Randomized Trial of Image -Guided Stereotactic Radiation Therapy (IG-SRT) in Prostate… | N/A | terminated | Sep 22, 2016 | Weill Medical College of Cornell University | Lack of patient accruals. | Enrollment / accrual |
| NCT01811810 | Proton Therapy for High Risk Prostate Cancer | N/A | withdrawn | Mar 15, 2013 | Abramson Cancer Center at Penn Medicine | Unable to recruit | Enrollment / accrual |
| NCT00537849 | Investigational Study For the Treatment of Localized (T1c/T2a) Prostate Cancer With High… | N/A | withdrawn | Oct 1, 2007 | SonaCare Medical | Sponsor withdrew request to conduct study | Other (stated, no rule matched) |
| NCT02501759 | Transrectal MRI-Guided Biopsy in Identifying Cancer in Patients With Suspected Prostate… | N/A | terminated | Jul 17, 2015 | OHSU Knight Cancer Institute | Low enrollment and funding loss. | Enrollment / accrual |
| NCT00996502 | Study of Bevacizumab and Erlotinib for Patients With Hormone Refractory Prostate Cancer | Phase 1 / Phase 2 | terminated | Oct 16, 2009 | Columbia University | Poor enrollment; PI left the institution | Investigator |
| NCT01478828 | Pre-Prostatectomy Lovastatin on Prostate Cancer | N/A | terminated | Nov 23, 2011 | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | The study was stopped due to an unanticipated serious adverse event. | Safety / toxicity |
| NCT02742259 | Validation of the Prostate Cancer Assay - Beta+Pivotal(VPCA-B+PIV) | — | withdrawn | Apr 19, 2016 | Celsee Diagnostics | No enrolled participants | Enrollment / accrual |
| NCT01994590 | Dovitinib (TKI258) and Abiraterone Acetate in Metastatic Castrate-Resistant Prostate… | Phase 2 | terminated | Nov 26, 2013 | M.D. Anderson Cancer Center | Sponsor stopped supplying study drug | Other (stated, no rule matched) |
| NCT01445054 | 111 Indium CHX-A DTPA Trastuzumab (Indium-Herceptin) for Imaging Breast Cancer | Early Phase 1 | terminated | Oct 3, 2011 | National Cancer Institute (NCI) | not stated | Not stated |
| NCT01163084 | Leuprolide Acetate or Goserelin Acetate With or Without Vismodegib Followed by Surgery in… | Phase 1 / Phase 2 | terminated | Jul 15, 2010 | National Cancer Institute (NCI) | not stated | Not stated |
| NCT02459912 | Unilateral Nerve-Sparing Cryoablation for Low-Risk, Clinically Localized, Unilateral…(POTENT-C) | Phase 2 | terminated | Jun 2, 2015 | NYU Langone Health | Patient recruitment | Enrollment / accrual |
| NCT03227744 | A Pilot Study of Prostate Cancer-specific Anxiety in Active Surveillance | N/A | terminated | Jul 24, 2017 | NYU Langone Health | Study has been terminated | Other (stated, no rule matched) |
| NCT01741753 | BKM120+Abiraterone Acetate for Metastatic CRPC | Phase 1 | terminated | Dec 5, 2012 | Dana-Farber Cancer Institute | Due to slow accrual the supllier of BKM120 asked we cease further enrollment. | Enrollment / accrual |
| NCT01275651 | Biomarkers in Bone Marrow and Blood Samples From Patients With Prostate Cancer Treated… | — | withdrawn | Jan 12, 2011 | Alliance for Clinical Trials in Oncology | Trial closure for NCI NCTN Transition | Other (stated, no rule matched) |
| NCT03147196 | Bicalutamide and Raloxifene Hydrochloride in Treating Patients With Prostate Cancer… | Phase 2 | withdrawn | May 10, 2017 | Mayo Clinic | lack of accrual | Enrollment / accrual |
| NCT02478125 | Pilot Study of Mobilization and Treatment of Disseminated Tumor Cells in Men With… | Phase 1 | terminated | Jun 23, 2015 | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | Low accrual | Enrollment / accrual |
| NCT01262664 | A First-in-Man, Phase I Evaluation of A Single Cycle of Prohibitin Targeting Peptide 1 in… | Phase 1 | terminated | Dec 17, 2010 | M.D. Anderson Cancer Center | Terminated per PI's request | Other (stated, no rule matched) |
| NCT00544076 | ED Recovery in Men Age </=65 Treated With Bilateral Nerve Sparing Robotic Assisted… | Phase 3 | terminated | Oct 16, 2007 | City of Hope Medical Center | Accrual too slow | Enrollment / accrual |
| NCT00924807 | Safety Study of Sorafenib With Androgen Deprivation and Radiotherapy to Treat Prostate… | Phase 1 / Phase 2 | terminated | Jun 19, 2009 | Beth Israel Medical Center | Sponsor closed the trial | Other (stated, no rule matched) |
| NCT00526591 | Everolimus in Treating Patients With Newly Diagnosed Localized Prostate Cancer | Phase 2 | terminated | Sep 10, 2007 | Jorge A. Garcia, MD | Slow accrual | Enrollment / accrual |
| NCT01703065 | Cabozantinib in Men With Castration-Resistant Prostate Cancer | Phase 2 | terminated | Oct 10, 2012 | University of Washington | Closed 2017 for low accrual. Last data for primary outcome on 02Feb2015. | Enrollment / accrual |
| NCT02494713 | Hormonal Therapy and Chemotherapy Followed by Prostatectomy in Patients With Prostate… | Phase 2 | terminated | Jul 10, 2015 | The University of Texas Health Science Center, Houston | slow enrollment; resource re-allocation | Enrollment / accrual |
| NCT00963300 | MRI in Assessing Hypoxia in Patients With Localized Prostate Cancer Undergoing… | N/A | withdrawn | Aug 21, 2009 | University of Texas Southwestern Medical Center | Project Never Initiated - no human subjects were enrolled and no data regarding humans was… | Enrollment / accrual |
| NCT03296124 | Prognostic Value of Androgen Receptor Expression and Mutations Within Oncogenes and Tumor…(PRX32) | — | withdrawn | Sep 28, 2017 | University of Florida | This project currently does not have any subjects enrolled due to other PI priorities. | Enrollment / accrual |
| NCT00103376 | Bortezomib With or Without Hormone Therapy in Treating Patients With Relapsed Prostate… | Phase 2 | terminated | Feb 8, 2005 | Medical University of South Carolina | Low Accrual | Enrollment / accrual |
| NCT00080782 | Doxorubicin and Strontium-89 With or Without Celecoxib in Treating Patients With… | Phase 2 | terminated | Apr 8, 2004 | M.D. Anderson Cancer Center | Low accrual due to competing trial. | Enrollment / accrual |
| NCT00851682 | Feasibility Study of Prostate Tumor Localization for Focal Cryoablation of Prostate… | N/A | terminated | Feb 26, 2009 | Washington University School of Medicine | Enrollment was stopped and will not resume. Participants are no longer being examined. | Enrollment / accrual |
| NCT02450201 | MRI With C13 Pilot Study Prostate Cancer | Early Phase 1 | terminated | May 21, 2015 | University of California, San Francisco | Low accrual | Enrollment / accrual |
| NCT01354951 | Assessing the Potential for Reduced Toxicity Using Focal Brachytherapy in Early Stage,… | Phase 2 | terminated | May 17, 2011 | Memorial Sloan Kettering Cancer Center | Lack of accrual | Enrollment / accrual |
| NCT00670046 | Valproic Acid in Treating Patients With Progressive, Non-Metastatic Prostate Cancer | Phase 2 | terminated | May 1, 2008 | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | The study was terminated per the PI decision. | Other (stated, no rule matched) |
| NCT01795365 | Active Surveillance of 2 Groups of Patients With Localized Prostate Cancer | N/A | terminated | Feb 20, 2013 | Centre Hospitalier Universitaire Vaudois | Participants are no longer being examined and receiving intervention. | Other (stated, no rule matched) |
| NCT03014973 | Castration-resistant Prostate Cancer and Intra-prostatic Hormonal Status(HORM) | N/A | withdrawn | Jan 9, 2017 | Hopital Foch | not stated | Not stated |
| NCT00953576 | Ketoconazole, Hydrocortisone, Dutasteride and Lapatinib (KHAD-L) in Prostate Cancer(KHLAD) | Phase 1 / Phase 2 | terminated | Aug 6, 2009 | Dana-Farber Cancer Institute | The study terminated early due to concerns about drug toxicity. | Safety / toxicity |
| NCT00562341 | Effect of Lap-Band Induced Weight Loss on Serum PSA Levels | — | withdrawn | Nov 22, 2007 | Maimonides Medical Center | enrollment challenges | Enrollment / accrual |
| NCT01618838 | Endoscopic Evaluation of Late Rectal Injury Following CyberKnife Radiosurgery for… | N/A | terminated | Jun 13, 2012 | Georgetown University | The study only accrued 4 patients in 2 years, far below target (40). It was closed with no subject… | Enrollment / accrual |
| NCT00922818 | Study of Anatomic Nerve Sparing Radical Perineal Prostatectomy(RPP) | — | withdrawn | Jun 17, 2009 | Maimonides Medical Center | recruitment issues | Enrollment / accrual |
| NCT00527124 | Docetaxel and Prednisone With or Without Cediranib in Treating Patients With Metastatic… | Phase 2 | terminated | Sep 10, 2007 | National Cancer Institute (NCI) | Closure was recommended by CTEP due to slow accrual. | Enrollment / accrual |
| NCT01439542 | FASTR: Fairly Brief Androgen Suppression and Stereotactic Radiotherapy for High Risk…(FASTR) | Phase 2 | terminated | Sep 23, 2011 | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | Higher then expected Gr3 GU/GI toxicity | Safety / toxicity |
| NCT02179762 | Vigorous or Moderate Exercise in Enhancing Active Surveillance in Patients With Localized…(EASE) | N/A | withdrawn | Jul 2, 2014 | Case Comprehensive Cancer Center | Insufficient staff | Other (stated, no rule matched) |
| NCT02694380 | Measuring the Effect of Radiation Therapy on Patient Activity Levels | — | terminated | Feb 29, 2016 | University of Pittsburgh | Low accrual | Enrollment / accrual |
| NCT03465345 | Study of Metformin Plus Oligomeric Procyanidin Complex for Pharmacologic Manipulation of… | Phase 1 | withdrawn | Mar 14, 2018 | Medical University of South Carolina | Study was stopped to pursue a new treatment plan with a new study. | Other (stated, no rule matched) |
| NCT02053311 | Orteronel Maintenance Therapy in Patients With mCRPC Previously Treated With Novel… | Phase 3 | withdrawn | Feb 3, 2014 | Swiss Cancer Institute | Due to former trials, drug has not demonstrated a clinical profile sufficient to move forward in… | Other (stated, no rule matched) |
| NCT02250313 | PASCUAL (Prostate Assay Specific Clinical Utility at Launch) Study(PASCUAL) | — | terminated | Sep 26, 2014 | MDx Health | Pending final analysis for termination | Other (stated, no rule matched) |
| NCT03073473 | Evaluation of the NantHealth GPS Cancer Test in Patients With Advanced Cancers | — | terminated | Mar 8, 2017 | Cota Inc. | Poor accrual | Enrollment / accrual |
| NCT01983709 | Allogeneic Human Bone Marrow Derived Mesenchymal Stem Cells in Localized Prostate Cancer(MSC) | Phase 1 | terminated | Nov 14, 2013 | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | Study was Terminated by PI due to low accrual | Enrollment / accrual |
| NCT00458549 | Polyunsaturated Fatty Acids in Treating Patients With Prostate Cancer Undergoing Prostate… | N/A | terminated | Apr 11, 2007 | Dana-Farber Cancer Institute | Slow Accrual | Enrollment / accrual |
| NCT01335204 | Ph Ib/IIa Study of Cabazitaxel Plus Bavituximab in Castration-resistant Prostate Cancer | Phase 1 / Phase 2 | terminated | Apr 14, 2011 | Medical University of South Carolina | lack of funding | Funding |
| NCT02491411 | Dexamethasone Prior to Re-treatment With Enzalutamide in Treating Patients With…(DEXTER) | N/A | terminated | Jul 8, 2015 | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | The study is terminated due to lower enrollment | Enrollment / accrual |
Stop reasons are registrant-reported free text and are displayed verbatim (truncated; hover for the full text). Categories come from explicit keyword rules and are never inferred from the study design, sponsor or outcome; a study that stopped for several reasons is filed under the first rule that matched. A TERMINATED status does not imply a negative result.
Data updated 23 days agoSource updated May 10, 2019source: clinicaltrials