Clinical trial · Interventional
Feasibility Study of Prostate Tumor Localization for Focal Cryoablation of Prostate Carcinoma
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Why stopped (as posted): Enrollment was stopped and will not resume. Participants are no longer being examined.
Summary
Brief summary (as posted)
The purpose of the present study is to find out if MRI techniques examining (1) the motion of water molecules in the prostate (diffusion sensitive MRI), (2) the difference in blood flow to the prostate (dynamic contrast enhanced MRI), and (3) differences in chemical composition of the prostate (MR spectroscopy), can be used to detect prostate cancer early and non-invasively. Localization of the cancer within the prostate would be of particular importance in focal cryoablation of prostate carcinoma which we hope to improve as a result of this project. Additional aim of the study is to correlate expression of genes believed to pay a role in prostate cancer with MRI findings.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Prostate Cancer | Malignant Prostate Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| MRI scan | Device | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- OTHER
- label
- Radical prostatectomy patients
- description
- Patients who have been diagnosed with prostate cancer and are scheduled to undergo radical prostatectomy and have not received any preoperative treatment for prostate cancer.
- interventionNames
- Device: MRI scan
- type
- OTHER
- label
- Brachytherapy patients
- description
- Patients who have been diagnosed with prostate cancer and are scheduled to undergo brachytherapy and have not received any preoperative treatment for prostate cancer.
- interventionNames
- Device: MRI scan
Primary outcomes (1)
- measure
- Improved Accuracy of Prostate Cancer Detection by MRI Scan.
Eligibility
Eligibility (as posted)
- Sex
- Male
- Minimum age
- 20 Years
- Maximum age
- 85 Years
Show eligibility criteria text
Inclusion Criteria: * patients who have been diagnosed with prostate cancer and are scheduled for radical prostatectomy or for brachytherapy * patients who have not received any preoperative treatment for their diagnosis of prostate cancer Exclusion Criteria: * patients with implants that are electronically, magnetically, or mechanically active * patients with intracranial aneurysm clips * patients who have undergone cosmetic eyelid surgery * patients with history of pheochromocytoma, insulinoma and acute glaucoma * patients with estimated glomerular filtration rate (eGFR) less than 60 ml/min/1.73m2
References
Publications (0)
Data not yet available