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Clinical trials · failure tracking
Oncology studies whose overall status is TERMINATED, WITHDRAWN or SUSPENDED on ClinicalTrials.gov, with the stop reason exactly as the registrant posted it. A category is attached only when an explicit keyword rule matches the text; CancerIndex never infers why a study stopped.
876 stopped studies mapped to Malignant Male Reproductive System Neoplasm and descendants · 91% state a reason
Over the 876 studies matching the cancer, status and year filters (the category filter does not change this chart). Each study is counted once, in the first matching category; greyed bars are studies whose text matched no rule or was empty.
Computedrules ci-stop-reasons-v1 · keyword matching only
A category is assigned when one of its keywords appears in the posted text (case-insensitive, whole words). Rules are tested in this order and the first match wins; every match is kept in the API (reasonMatches).
| NCT | Title | Phase | Status | First posted | Lead sponsor | Why stopped (as posted) | Category |
|---|---|---|---|---|---|---|---|
| NCT02421575 | Hydroxychloroquine in Blocking Autophagy in Patients With Prostate Cancer Undergoing… | Early Phase 1 | terminated | Apr 20, 2015 | Rutgers, The State University of New Jersey | slow accrual | Enrollment / accrual |
| NCT00879619 | Taxotere/Prednisone Plus Sunitinib in Chemotherapy-Naïve, Hormone Refractory Prostate… | Phase 1 / Phase 2 | terminated | Apr 10, 2009 | John P. Fruehauf | Terminated due to slow accrual. | Enrollment / accrual |
| NCT01762956 | Pelvic Floor Muscles Training in Men Undergoing Radiotherapy for Prostate Cancer:… | N/A | terminated | Jan 8, 2013 | University of Sao Paulo | Unobtainable sample size | Other (stated, no rule matched) |
| NCT01699672 | Group-based or Individual Information About Disease and Treatment Plan | N/A | terminated | Oct 4, 2012 | Norwegian University of Science and Technology | Problems recruiting patients (not willing, travel time, no respons) | Enrollment / accrual |
| NCT01748110 | Health Interventions in Men Undergoing Radical Prostatectomy(HIM-UP) | N/A | withdrawn | Dec 12, 2012 | Johns Hopkins University | Funding could not be secured | Funding |
| NCT01913197 | Using Magnetic Resonance Imaging (MRI) to Guide Differential-Dose Prostate Brachytherapy | Phase 1 / Phase 2 | terminated | Jul 31, 2013 | St. Luke's-Roosevelt Hospital Center | low enrollment | Enrollment / accrual |
| NCT00686036 | Trial Assessing Zactima Against Placebo in Prostate Cancer Subjects Undergoing…(ZENITH) | Phase 2 | terminated | May 29, 2008 | Genzyme, a Sanofi Company | Slow recruitment | Enrollment / accrual |
| NCT00598858 | Neoadjuvant Docetaxel on Newly Diagnosed Intermediate and High Grade Cancer of the…(2007-5904) | Phase 2 | withdrawn | Jan 23, 2008 | John P. Fruehauf | Halted due to zero accrual and lack of funding | Enrollment / accrual |
| NCT00565227 | Phase I Study of Vorinostat in Combination With Docetaxel in Patients With Advanced and… | Phase 1 | terminated | Nov 29, 2007 | University of Michigan Rogel Cancer Center | closed due to toxicity | Safety / toxicity |
| NCT02404428 | Utilizing MRI to Study the Effect of Sulforaphane on Prostate Cancer(ESCAPE-ING) | N/A | terminated | Mar 31, 2015 | Quadram Institute Bioscience | Problems with recruitment | Enrollment / accrual |
| NCT02645591 | Randomized AmnioFix Study During Radical Prostatectomy | Phase 2 | withdrawn | Jan 1, 2016 | M.D. Anderson Cancer Center | not stated | Not stated |
| NCT00767845 | Symptom Management in African-American Men With Localized Prostate Cancer | — | withdrawn | Oct 7, 2008 | Baylor College of Medicine | No subjects were enrolled here or at UCSF. | Enrollment / accrual |
| NCT00933426 | Lenalidomide and Paclitaxel in Prostate Cancer | Phase 1 | terminated | Jul 7, 2009 | M.D. Anderson Cancer Center | Terminated early due to slow accrual as Phase I dose escalation study. | Enrollment / accrual |
| NCT01705405 | Merging of Endoscopic and Ultrasound Images for Laparoscopic Surgery(FEE) | N/A | terminated | Oct 12, 2012 | AdministrateurCIC | due to a problem of device | Other (stated, no rule matched) |
| NCT01761812 | Multiparametric MRI for Prostate Cancer Localization and Characterization: New Methods | N/A | terminated | Jan 7, 2013 | Sunnybrook Health Sciences Centre | Inadequate accrual | Enrollment / accrual |
| NCT02279576 | Study With Pazopanib and Weekly Paclitaxel in Penile Carcinoma (PAZOPEN-SOGUG)(PAZOPEN-SOGUG) | Phase 2 | terminated | Oct 31, 2014 | Spanish Oncology Genito-Urinary Group | The low recruitment of patients will not allow to complete the study with the required number of… | Enrollment / accrual |
| NCT02656563 | Radium 223 Following Intermittent ADT(RAND) | Phase 2 | withdrawn | Jan 15, 2016 | Canadian Urology Research Consortium | not stated | Not stated |
| NCT02169063 | Carbon-11 Acetate and Fluorine F 18 Sodium Fluoride PET as a Biomarker of Treatment… | N/A | withdrawn | Jun 20, 2014 | University of Washington | not stated | Not stated |
| NCT00691899 | A Study to Assess the Effects of MK0822 in Prolonging Time to First Bone Metastasis in… | Phase 3 | withdrawn | Jun 6, 2008 | Merck Sharp & Dohme LLC | Withdrawn for administrative reasons | Other (stated, no rule matched) |
| NCT02281279 | Rituximab, Romidepsin, and Lenalidomide in Treating Patients With Recurrent or Refractory… | Phase 1 / Phase 2 | withdrawn | Nov 3, 2014 | Mayo Clinic | not stated | Not stated |
| NCT01379378 | Male Stress Urinary Incontinence and Sexual Health | — | withdrawn | Jun 23, 2011 | Stanford University | not stated | Not stated |
| NCT02678520 | Clinical Trial Comparing 3-D RT vs. IMRT in Post- Prostatectomy Prostate Cancer Patients | Phase 2 | withdrawn | Feb 9, 2016 | University of Kansas Medical Center | PI no longer at institution. Study terminated prior to enrolling subjects. | Enrollment / accrual |
| NCT01652014 | Single or Double Donor Umbilical Cord Blood Transplant in Treating Patients With… | Phase 2 | withdrawn | Jul 27, 2012 | University of Medicine and Dentistry of New Jersey | Funding unavailable | Funding |
| NCT00003858 | Mitoxantrone Following Surgery in Treating Patients With Prostate Cancer at High Risk for… | Phase 2 | withdrawn | Sep 14, 2004 | Alliance for Clinical Trials in Oncology | The study was not activated. | Other (stated, no rule matched) |
| NCT01481441 | Quantification of Contrast Enhanced Ultrasound (CEUS) in the Detection of Prostate Cancer(AMC_2011_190) | N/A | terminated | Nov 29, 2011 | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | New study protocol started including targeted biopsies | Other (stated, no rule matched) |
| NCT00861471 | Docetaxel (Taxotere) and Imatinib Mesylate (Gleevec) in Hormone Refractory Prostate Cancer | Phase 1 / Phase 2 | terminated | Mar 13, 2009 | NYU Langone Health | due to slow accrual | Enrollment / accrual |
| NCT00003682 | Methylprednisolone With or Without Doxorubicin in Treating Patients With Metastatic… | Phase 3 | terminated | Jan 27, 2004 | UNICANCER | lack of inclusions | Other (stated, no rule matched) |
| NCT00664196 | Trial of Anti-PSMA Designer T Cells in Advanced Prostate Cancer After Non-Myeloablative… | Phase 1 | suspended | Apr 22, 2008 | Roger Williams Medical Center | Funding | Funding |
| NCT02140138 | An Open Label Randomised Trial of RNActive® Cancer Vaccine in High Risk and Intermediate… | Phase 2 | terminated | May 16, 2014 | CureVac | Recruitment was terminated after enrolment of 35 instead of 36 evaluable patients for… | Enrollment / accrual |
| NCT01658527 | TAK-700 in Castration Resistant Prostate Cancer | Phase 2 | withdrawn | Aug 7, 2012 | European Organisation for Research and Treatment of Cancer - EORTC | Pharmaceutical company has terminated orteronel (TAK-700) development for Prostate Cancer | Sponsor / business decision |
| NCT00503984 | A Phase I/II Study of Azacitidine, Docetaxel, and Prednisone for Metastatic Prostate… | Phase 1 / Phase 2 | terminated | Jul 19, 2007 | University of Miami | Withdrawal of Funding | Funding |
| NCT00216060 | Risedronate to Prevent Skeletal Related Events in Patients With Metastatic Prostate… | Phase 3 | terminated | Sep 22, 2005 | Christopher Sweeney, MBBS | Terminated due to low accrual | Enrollment / accrual |
| NCT01173146 | Imaging of Residual Tumor During Prostatectomy | — | withdrawn | Jul 30, 2010 | Spectros Corporation | Costs for antibody production rose; supplemental funding request not approved. | Funding |
| NCT00985738 | Role of Dutasteride in Patients Undergoing 3D Mapping Biopsy in Early Stage Prostate… | Phase 2 | terminated | Sep 28, 2009 | University of Colorado, Denver | Low recruitment | Enrollment / accrual |
| NCT00801996 | Epidemiologic, Clinical and Genetic Profile of Prostate Cancer in Arab Countries(ProstateCA) | — | withdrawn | Dec 4, 2008 | Weill Medical College of Cornell University | Closed by Investigator | Investigator |
| NCT01981707 | F-choline PET in Early Response Assessment for Castration Resistant Prostatic Cancer(PRECHOL) | Phase 2 / Phase 3 | terminated | Nov 11, 2013 | University Hospital, Grenoble | enrollment default | Enrollment / accrual |
| NCT02512120 | Volume Controlled Ventilation vs Autoflow-volume Controlled Ventilation(VCVAFVCV) | N/A | withdrawn | Jul 30, 2015 | Korea University Anam Hospital | The backgroud of this study was not well discussed. | Other (stated, no rule matched) |
| NCT02749825 | Comparison of Trelstar Versus Lupron or Zoladex in Advanced Prostate Cancer | Phase 4 | terminated | Apr 25, 2016 | Pharmatech | Withdrawal of funding support | Funding |
| NCT01832831 | Anatomical and Functional Differences Between Continent and Incontinent Men Post Radical… | — | terminated | Apr 16, 2013 | University of Michigan | The study was completed as planned | Other (stated, no rule matched) |
| NCT00243646 | Implant and External Radiation for Prostate Cancer With or Without Hormonal Therapy: A… | Phase 3 | terminated | Oct 24, 2005 | Schiffler Cancer Center | poor accrual | Enrollment / accrual |
| NCT02110849 | Prostate Cancer Parameters for Patients Receiving Proton Treatment | — | withdrawn | Apr 10, 2014 | Indiana University | Closure of IU Health Proton Facility | Other (stated, no rule matched) |
| NCT00024167 | Chemotherapy With or Without Strontium-89 in Treating Patients With Prostate Cancer | Phase 3 | terminated | Jan 27, 2003 | M.D. Anderson Cancer Center | Terminated due to slow accrual | Enrollment / accrual |
| NCT01603420 | External Beam Radiation With or Without Chemotherapy to Treat High Risk Prostate Cancer | Phase 2 / Phase 3 | terminated | May 22, 2012 | Proton Collaborative Group | enrollment goals not met | Enrollment / accrual |
| NCT01220427 | Micro-RNA Expression Profiles in High Risk Prostate Cancer | — | terminated | Oct 13, 2010 | Wuerzburg University Hospital | not stated | Not stated |
| NCT00122265 | Exploring Genomic, Proteomic and Dosimetric Determinants of Late Toxicity After Three… | — | terminated | Jul 22, 2005 | AHS Cancer Control Alberta | not stated | Not stated |
| NCT00523471 | Blood Test to Measure DNA Damage in Blood | — | terminated | Aug 31, 2007 | AHS Cancer Control Alberta | not stated | Not stated |
| NCT02014831 | Efficacy and Safety of Cetuximab in Metastatic Penile Carcinoma (PENILANE)(PENILANE) | Phase 2 | withdrawn | Dec 18, 2013 | Centre Leon Berard | Industry decline to supply study drug | Drug supply |
| NCT02035124 | Cabazitaxel and BKM120 in Patients With Metastatic Castrate-Resistant Prostate Cancer… | Phase 2 | withdrawn | Jan 14, 2014 | SCRI Development Innovations, LLC | Study withdrawn due to slow accrual. No patients were enrolled. | Enrollment / accrual |
| NCT02130947 | Exercise Intervention for Pts With Metastatic Castration-Resistant Prostate Cancer… | N/A | withdrawn | May 6, 2014 | UNC Lineberger Comprehensive Cancer Center | We were not able to accrue any participants. | Enrollment / accrual |
| NCT02621684 | Physical Activity Intervention in African American Men After Radical Prostatectomy | N/A | withdrawn | Dec 3, 2015 | Washington University School of Medicine | Not able to enroll any participants due to disinterest | Enrollment / accrual |
Stop reasons are registrant-reported free text and are displayed verbatim (truncated; hover for the full text). Categories come from explicit keyword rules and are never inferred from the study design, sponsor or outcome; a study that stopped for several reasons is filed under the first rule that matched. A TERMINATED status does not imply a negative result.
Data updated 23 days agoSource updated Feb 2, 2017source: clinicaltrials