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Clinical trials · failure tracking
Oncology studies whose overall status is TERMINATED, WITHDRAWN or SUSPENDED on ClinicalTrials.gov, with the stop reason exactly as the registrant posted it. A category is attached only when an explicit keyword rule matches the text; CancerIndex never infers why a study stopped.
876 stopped studies mapped to Malignant Male Reproductive System Neoplasm and descendants · 91% state a reason
Over the 876 studies matching the cancer, status and year filters (the category filter does not change this chart). Each study is counted once, in the first matching category; greyed bars are studies whose text matched no rule or was empty.
Computedrules ci-stop-reasons-v1 · keyword matching only
A category is assigned when one of its keywords appears in the posted text (case-insensitive, whole words). Rules are tested in this order and the first match wins; every match is kept in the API (reasonMatches).
| NCT | Title | Phase | Status | First posted | Lead sponsor | Why stopped (as posted) | Category |
|---|---|---|---|---|---|---|---|
| NCT01200810 | Bicalutamide and RO4929097 in Treating Patients With Previously Treated Prostate Cancer | Phase 2 | terminated | Sep 14, 2010 | National Cancer Institute (NCI) | Drug was no longer available | Other (stated, no rule matched) |
| NCT01260909 | Real-Time MV/kV Image Guided Radiation Therapy | — | withdrawn | Dec 15, 2010 | Stanford University | Business decision | Sponsor / business decision |
| NCT00524589 | Calcitriol and Dexamethasone in Treating Patients With Prostate Cancer That Did Not… | Phase 2 | terminated | Sep 3, 2007 | Roswell Park Cancer Institute | closed due to futility | Efficacy / futility |
| NCT02793219 | Provenge Followed by Docetaxel in Castration-Resistant Prostate Cancer | Phase 2 | withdrawn | Jun 8, 2016 | The University of Texas Health Science Center, Houston | Dendreon was sold and new company decided not to fund study. | Funding |
| NCT02793765 | Docetaxel Followed by Provenge in Metastatic Prostate Cancer | Phase 2 | withdrawn | Jun 8, 2016 | The University of Texas Health Science Center, Houston | Dendreon was sold and new company decided not to fund study. | Funding |
| NCT01748890 | A Pilot Trial of Sonoelastography for Planning Tumor-targeted Prostate Biopsy | N/A | terminated | Dec 13, 2012 | Massachusetts General Hospital | Insufficient recruitment | Enrollment / accrual |
| NCT02564549 | MRI-Based Active Surveillance to Avoid the Risks of Serial Biopsies in Men With Low-Risk… | N/A | terminated | Sep 30, 2015 | Virginia Commonwealth University | Study halted prematurely and will not resume | Other (stated, no rule matched) |
| NCT02232672 | Choline PET/CT vs. MeAIB PET/CT in Prostate Cancer | N/A | withdrawn | Sep 5, 2014 | Odense University Hospital | not stated | Not stated |
| NCT00480857 | Salvage Radiation Therapy and Taxotere for PSA Failure After Radical Prostatectomy | Phase 2 | terminated | May 31, 2007 | University of Michigan Rogel Cancer Center | Lack of funding. | Funding |
| NCT03173807 | Prostate Nutrition and Exercise STudy (ProNEST)(ProNEST) | N/A | withdrawn | Jun 2, 2017 | University of Pittsburgh | Unable to find adequate funding | Funding |
| NCT00531687 | Trial of Paclitaxel, Gemcitabine and Cisplatin in Patients With Relapsing Germ Cell Cancer | Phase 2 | terminated | Sep 19, 2007 | Rigshospitalet, Denmark | slow accrual | Enrollment / accrual |
| NCT01145508 | Docetaxel and Prednisone With or Without Vaccine Therapy in Treating Patients With… | Phase 2 | terminated | Jun 16, 2010 | National Cancer Institute (NCI) | Poor accrual | Enrollment / accrual |
| NCT02454595 | Registry to Measure the Impact of Adding Genomic Testing | — | terminated | May 27, 2015 | Myriad Genetic Laboratories, Inc. | lack of enrollment | Enrollment / accrual |
| NCT01866423 | Orteronel in Treating Patients With Metastatic Hormone-Resistant Prostate Cancer | Phase 2 | terminated | May 31, 2013 | University of Southern California | Not progressing toward scientific goals | Other (stated, no rule matched) |
| NCT01677845 | Hypo-Fractionated Radiation Therapy for Localized Prostate Cancer | Phase 1 | terminated | Sep 3, 2012 | NYU Langone Health | PI no longer with the institution | Other (stated, no rule matched) |
| NCT02810886 | Prospective Evaluation of 68Ga-PSMA PET-CT for Recurrence Detection of Prostate Cancer…(ProsPERo) | Phase 2 | withdrawn | Jun 23, 2016 | Jules Bordet Institute | Recent publications demonstrating the clinical interest in performing 68Ga-PSMA for recurrence… | Other (stated, no rule matched) |
| NCT00898833 | Plasma and Urine Samples From Patients With Hormone-Refractory Prostate Cancer Enrolled… | — | terminated | May 12, 2009 | Alliance for Clinical Trials in Oncology | The proposed work could not be completed. | Other (stated, no rule matched) |
| NCT01419795 | Lenalidomide With or Without Rituximab in Treating Patients With Progressive or Relapsed… | Phase 2 | terminated | Aug 18, 2011 | Fred Hutchinson Cancer Center | Low accrual | Enrollment / accrual |
| NCT02307552 | Transurethral Ultrasonic Imaging For Detection and Classification of Prostate Cancer | N/A | terminated | Dec 4, 2014 | University of California, Irvine | The probe could not be anchored in place and would rotate about its axis, thus comparison was… | Other (stated, no rule matched) |
| NCT02042053 | PET/MR Assessment of Sipuleucel T Treatment for Metastatic Castration Resistant Prostate… | N/A | terminated | Jan 22, 2014 | NYU Langone Health | Due to PI leaving the institution | Other (stated, no rule matched) |
| NCT00003622 | Vinorelbine Plus Paclitaxel in Treating Patients With Metastatic Prostate Cancer That Is… | Phase 2 | withdrawn | May 3, 2004 | James Ahlgren | No recruitment | Enrollment / accrual |
| NCT03211052 | A Study of Neoadjuvant TAK-700 and Leuprorelin Acetate Followed by Surgery Versus Surgery…(NEPTUNE) | Phase 2 | terminated | Jul 7, 2017 | Centre of Experimental Medicine | IMP no longer available | Other (stated, no rule matched) |
| NCT00536991 | Calcitriol in Combination With Ketoconazole and Therapeutic Hydrocortisone in Treating… | Phase 1 / Phase 2 | terminated | Sep 28, 2007 | Roswell Park Cancer Institute | difficult to recruit | Enrollment / accrual |
| NCT00084864 | Calcitriol and Dexamethasone Before Radical Prostatectomy in Treating Patients With… | Phase 2 | terminated | Jun 11, 2004 | Roswell Park Cancer Institute | sample size is too small to draw a conclusion | Other (stated, no rule matched) |
| NCT01558492 | Carboplatin and Paclitaxel in Patients With Metastatic, Castrate-Resistant Prostate Cancer | Phase 2 | terminated | Mar 20, 2012 | Weill Medical College of Cornell University | Poor accrual | Enrollment / accrual |
| NCT01338012 | Sipuleucel-T in Metastatic Castrate Resistant Prostate Cancer(mCRPC) | Phase 2 | terminated | Apr 19, 2011 | Dendreon | Administrative reasons. | Other (stated, no rule matched) |
| NCT01642732 | Study of Everolimus Added to Combined Hormonal and Radiation Therapy for High Risk… | Phase 1 | terminated | Jul 17, 2012 | University of Michigan Rogel Cancer Center | Lack of accrual and funding expires in June, 2014. | Enrollment / accrual |
| NCT02429804 | NaF/FDG PET/MRI in Measuring Response to Radium Ra 223 Dichloride in Patients With… | Phase 1 | terminated | Apr 29, 2015 | Stanford University | Accrual factor | Enrollment / accrual |
| NCT00088881 | Rituximab, Combination Chemotherapy, and 90-Yttrium Ibritumomab Tiuxetan for Patients… | Phase 2 | terminated | Aug 5, 2004 | National Cancer Institute (NCI) | not stated | Not stated |
| NCT01385293 | BKM120 in Metastatic Castration-resistant Prostate Cancer | Phase 2 | terminated | Jun 30, 2011 | Andrew J. Armstrong, MD | The trial was stopped at the first stage due to futility | Efficacy / futility |
| NCT01940237 | A Pilot Trial of Interpersonal Psychotherapy for the Treatment of Depression in Patients… | N/A | terminated | Sep 12, 2013 | New York State Psychiatric Institute | Low recruitment | Enrollment / accrual |
| NCT01215032 | Metformin in Castration-Resistant Prostate Cancer | Phase 2 | terminated | Oct 5, 2010 | Massachusetts General Hospital | slow accrual, competing clinical trials | Enrollment / accrual |
| NCT01735396 | Abiraterone Acetate Trial in African American Prostate Cancer Patients | Phase 2 | terminated | Nov 28, 2012 | Icahn School of Medicine at Mount Sinai | poor accrual | Enrollment / accrual |
| NCT01828476 | Navitoclax and Abiraterone Acetate With or Without Hydroxychloroquine in Treating… | Phase 2 | terminated | Apr 10, 2013 | Rutgers, The State University of New Jersey | The Investigator left the organization. | Investigator |
| NCT00244894 | Acupuncture in Treating Hot Flashes in Patients With Prostate Cancer | N/A | terminated | Oct 27, 2005 | OHSU Knight Cancer Institute | not stated | Not stated |
| NCT00459810 | Paclitaxel Poliglumex and Estradiol in Treating Patients With Stage IV Prostate Cancer | Phase 2 | terminated | Apr 13, 2007 | OHSU Knight Cancer Institute | not stated | Not stated |
| NCT00482274 | Docetaxel in Treating Patients With Relapsed Prostate Cancer | Phase 2 | terminated | Jun 5, 2007 | OHSU Knight Cancer Institute | Drug supplier stopped funding due to loss of study drug (docetaxel) patent. | Funding |
| NCT01913015 | Dietary Fat Levels and Abiraterone Acetate Uptake in Patients With Metastatic… | Phase 1 | terminated | Jul 31, 2013 | OHSU Knight Cancer Institute | After enrollment of the first 3 subjects, an interim assessment was conducted. Comparing DBS… | Enrollment / accrual |
| NCT02840162 | Pre-Prostatectomy Celecoxib or Placebo | Phase 2 | terminated | Jul 21, 2016 | OHSU Knight Cancer Institute | Drug safety concerns | Safety / toxicity |
| NCT00937417 | S0716 Vandetanib and Docetaxel in Treating Patients With Advanced Solid Tumors | Phase 1 | withdrawn | Jul 13, 2009 | SWOG Cancer Research Network | Withdrawn because SWOG no longer pursuing this study at this time | Other (stated, no rule matched) |
| NCT02247960 | Antibiotic Prophylaxis for Urinary Catheter Removal After Radical Prostatectomy(Abx) | N/A | terminated | Sep 25, 2014 | University of Rochester | Interim analysis determined that the study should be concluded for futility. | Efficacy / futility |
| NCT02370355 | Molecular Characterization of CTCs and ctDNA in Blood and Plasma Samples From Patients… | — | terminated | Feb 24, 2015 | University of Southern California | Sponsor decided not to pursue study | Sponsor / business decision |
| NCT01450683 | Study of Itraconazole in Castrate-resistant Prostate Cancer (CRPC) Post-chemotherapy | Phase 2 | terminated | Oct 12, 2011 | Stanford University | Low accrual | Enrollment / accrual |
| NCT02656615 | Abiraterone-Rechallenge Study for CRPC Patients(ABI-RE) | Phase 2 | terminated | Jan 15, 2016 | Aurelius Omlin | Lack of Patient accrual | Enrollment / accrual |
| NCT02483884 | PET/CT Imaging Study of the Safety and Diagnostic Performance of [68Ga]RM2 in Patients… | Phase 1 / Phase 2 | terminated | Jun 29, 2015 | Lantheus Biosciences Ltd. | Business decision | Sponsor / business decision |
| NCT01155791 | Phase I Sodium Selenite in Combination With Docetaxel in Castration-resistant Prostate… | Phase 1 | terminated | Jul 2, 2010 | Sandy Srinivas | not stated | Not stated |
| NCT01933022 | A Study in Patients With Metastatic Prostate Cancer to Assess How the Drug Eligard®,…(EFFECT) | Phase 4 | terminated | Aug 30, 2013 | Astellas Pharma Europe Ltd. | Termination due to high current screen rate failure and unreliable PSA mRNA assay. | Other (stated, no rule matched) |
| NCT01087580 | Docetaxel + Prednisone With or Without Radiation for Castrate Resistant Prostate Cancer | Phase 2 | withdrawn | Mar 16, 2010 | Northwestern University | not stated | Not stated |
| NCT01817738 | Trial of RNActive®-Derived Prostate Cancer Vaccine in Metastatic Castrate-refractory… | Phase 1 / Phase 2 | terminated | Mar 25, 2013 | CureVac | Follow up period after primary analysis was prematurely stopped because more mature data will not… | Other (stated, no rule matched) |
| NCT00823771 | A Pilot Study to Assess the Follow-up of Prostate Cancer Patients Who Have Undergone…(PROFUGO) | — | terminated | Jan 16, 2009 | Barwon Health | Data review showed that the study was underpowered to draw clear conlcusions | Other (stated, no rule matched) |
Stop reasons are registrant-reported free text and are displayed verbatim (truncated; hover for the full text). Categories come from explicit keyword rules and are never inferred from the study design, sponsor or outcome; a study that stopped for several reasons is filed under the first rule that matched. A TERMINATED status does not imply a negative result.
Data updated 23 days agoSource updated Dec 2, 2017source: clinicaltrials