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Clinical trials · failure tracking
Oncology studies whose overall status is TERMINATED, WITHDRAWN or SUSPENDED on ClinicalTrials.gov, with the stop reason exactly as the registrant posted it. A category is attached only when an explicit keyword rule matches the text; CancerIndex never infers why a study stopped.
2,225 stopped studies mapped to Malignant Genitourinary System Neoplasm and descendants · 88% state a reason
Over the 2,225 studies matching the cancer, status and year filters (the category filter does not change this chart). Each study is counted once, in the first matching category; greyed bars are studies whose text matched no rule or was empty.
Computedrules ci-stop-reasons-v1 · keyword matching only
A category is assigned when one of its keywords appears in the posted text (case-insensitive, whole words). Rules are tested in this order and the first match wins; every match is kept in the API (reasonMatches).
| NCT | Title | Phase | Status | First posted | Lead sponsor | Why stopped (as posted) | Category |
|---|---|---|---|---|---|---|---|
| NCT00040989 | BAY 56-3722 in Treating Patients With Recurrent, Unresectable, or Metastatic Kidney Cancer | Phase 2 | withdrawn | Jan 27, 2003 | Jonsson Comprehensive Cancer Center | not stated | Not stated |
| NCT00084565 | Paclitaxel, Topotecan, and Estramustine in Treating Patients With Metastatic… | Phase 2 | withdrawn | Jun 11, 2004 | Fox Chase Cancer Center | Study was never activated at Fox Chase Cancer Center. | Other (stated, no rule matched) |
| NCT00516750 | Gene Expression Profiling in Patients With Invasive Bladder Cancer Receiving… | Phase 2 | terminated | Aug 15, 2007 | Kyoto University | Withdrawn due to lack of enrollment. | Enrollment / accrual |
| NCT00566644 | Intrauterine Levonorgestrel and Observation or Observation Alone in Preventing Atypical… | Phase 3 | terminated | Dec 3, 2007 | St George's, University of London | Withdrawn due to poor accrual | Enrollment / accrual |
| NCT00748527 | Carboplatin With or Without Decitabine in Treating Patients With Progressive, Advanced… | Phase 2 | terminated | Sep 8, 2008 | Cancer Research UK | The study was "withdrawn" due to certain adverse events \[hypersensitivity\]. | Safety / toxicity |
| NCT00896467 | Psychological and Emotional Impact in Patients Undergoing Treatment For Metastatic Cancer… | — | terminated | May 11, 2009 | Centre Oscar Lambret | not stated | Not stated |
| NCT00003378 | Combination Chemotherapy in Treating Patients With Previously Untreated Stage III or… | Phase 1 | terminated | Aug 26, 2004 | Gynecologic Oncology Group | not stated | Not stated |
| NCT00006267 | Nitrocamptothecin in Treating Patients With Recurrent or Metastatic Ovarian Epithelial or… | Phase 2 | withdrawn | Jan 27, 2003 | Gynecologic Oncology Group | Never activated. | Other (stated, no rule matched) |
| NCT00084448 | Paclitaxel and Celecoxib in Treating Patients With Recurrent or Persistent… | Phase 2 | terminated | Jun 11, 2004 | Gynecologic Oncology Group | not stated | Not stated |
| NCT01073644 | Post Marketing Surveillance On The Safety And Tolerability Of Sunitinib Malate (Sutent)… | — | terminated | Feb 23, 2010 | Pfizer | The study was prematurely discontinued due to poor recruitment on 18th April 2013. There were no… | Safety / toxicity |
| NCT00098618 | Sorafenib and Interferon Alfa in Treating Patients With Locally Advanced or Metastatic… | Phase 2 | terminated | Dec 8, 2004 | National Cancer Institute (NCI) | not stated | Not stated |
| NCT01282333 | Veliparib, Cisplatin, and Gemcitabine Hydrochloride in Treating Patients With Advanced… | Phase 1 | terminated | Jan 25, 2011 | National Cancer Institute (NCI) | not stated | Not stated |
| NCT00956904 | Ultrasound-Guided Navigation in Robot-Assisted Laparoscopic Radical Prostatectomy | Early Phase 1 | terminated | Aug 11, 2009 | Johns Hopkins University | IRB approval expired. | Other (stated, no rule matched) |
| NCT01834183 | Tivozanib + Gemcitabine in Metastatic RCC | Phase 2 | withdrawn | Apr 17, 2013 | Dana-Farber Cancer Institute | Sponsor Aveo has withdrawn support for this trial. | Other (stated, no rule matched) |
| NCT00002478 | Etoposide in Treating Patients With Advanced Ovarian or Cervical Cancer | Phase 2 | terminated | Jun 9, 2004 | Gynecologic Oncology Group | not stated | Not stated |
| NCT00003179 | Surgery Plus Medroxyprogesterone in Preventing Endometrial Cancer | Phase 2 | terminated | Jan 27, 2003 | Gynecologic Oncology Group | not stated | Not stated |
| NCT00003380 | Liposomal Doxorubicin and Etoposide in Treating Patients With Recurrent or Persistent… | Phase 1 | terminated | Aug 16, 2004 | Gynecologic Oncology Group | not stated | Not stated |
| NCT00003382 | Combination Chemotherapy Consisting of Gemcitabine And Topotecan in Treating Patients… | Phase 1 | terminated | Jul 15, 2003 | Gynecologic Oncology Group | not stated | Not stated |
| NCT00003794 | Quality-of-Life Study of Patients With Previously Treated Ovarian Cancer | — | terminated | Oct 29, 2003 | Gynecologic Oncology Group | not stated | Not stated |
| NCT00006096 | Radiation Therapy With or Without Cisplatin in Treating Patients With Stage I, Stage II,… | Phase 3 | terminated | Sep 3, 2003 | Gynecologic Oncology Group | not stated | Not stated |
| NCT00017134 | Fenretinide Followed by Surgery Compared With Surgery Alone in Preventing Ovarian Cancer… | N/A | terminated | May 7, 2003 | Gynecologic Oncology Group | Withdrawn due to poor accrual | Enrollment / accrual |
| NCT00369954 | Gemcitabine and Carboplatin in Treating Patients With Persistent or Recurrent Ovarian… | Phase 2 | withdrawn | Aug 30, 2006 | Gynecologic Oncology Group | Trial was never activated | Other (stated, no rule matched) |
| NCT00477867 | Economic Outcomes in Patients With Stage III Ovarian Cancer Receiving Paclitaxel and… | N/A | withdrawn | May 24, 2007 | Gynecologic Oncology Group | Trial was never activated | Other (stated, no rule matched) |
| NCT01733836 | Prostate Cancer Active Surveillance Metformin Trial | Phase 2 | withdrawn | Nov 27, 2012 | University Health Network, Toronto | The reason for this decision is that this study is being merged with a larger multi-centre study… | Other (stated, no rule matched) |
| NCT00583622 | Bevacizumab Plus Gemcitabine, Docetaxel, Melphalan, and Carboplatin in Ovarian Cancer… | Phase 2 | terminated | Dec 31, 2007 | M.D. Anderson Cancer Center | Slow Accrual | Enrollment / accrual |
| NCT01383408 | Distinction Between Lung Cancer and Gynecological Cancers by Canine Scent Detection | Phase 2 | terminated | Jun 28, 2011 | Schillerhoehe Hospital | Inconsistent training status of sniffer dogs | Other (stated, no rule matched) |
| NCT00004856 | Trastuzumab in Treating Patients With Previously Treated, Locally Advanced, or Metastatic… | Phase 2 | terminated | Sep 30, 2003 | National Cancer Institute (NCI) | not stated | Not stated |
| NCT00005073 | Zoledronate Plus Standard Therapy Compared With Placebo Plus Standard Therapy to Prevent… | Phase 3 | terminated | Jun 18, 2004 | Novartis Pharmaceuticals | not stated | Not stated |
| NCT00043212 | Study of a Drug [DCVax (tm)-Prostate] to Treat Prostate Cancer When Hormone Therapy is no… | Phase 3 | withdrawn | Aug 8, 2002 | Northwest Biotherapeutics | Redirection of company goals | Sponsor / business decision |
| NCT01781442 | A Post Marketing Surveillance As Required By Philippine Food And Drug Administration | — | withdrawn | Feb 1, 2013 | Pfizer | not stated | Not stated |
| NCT00577980 | Testosterone in Castration-Resistant Prostate Cancer | Phase 2 | withdrawn | Dec 20, 2007 | M.D. Anderson Cancer Center | Zero accrual and failure to generate multicenter interest. | Enrollment / accrual |
| NCT00491075 | Pemetrexed Plus Gemcitabine in Renal Cell Cancer | Phase 2 | terminated | Jun 25, 2007 | M.D. Anderson Cancer Center | Closed early for poor accrual. | Enrollment / accrual |
| NCT00691977 | Radiation Therapy Followed by Surgery in High-Risk, Localized Carcinoma of the Prostate | Phase 1 | withdrawn | Jun 6, 2008 | Virginia Commonwealth University | poor accrual | Enrollment / accrual |
| NCT01466504 | Effect of Sorafenib or Regorafenib on P63 Expression and Keratinocyte Differentiation in… | — | terminated | Nov 8, 2011 | Dartmouth-Hitchcock Medical Center | Accrual did not meet expectations. Over nearly 2 years just 4 subjects were treated on study. The… | Enrollment / accrual |
| NCT00002819 | Chemotherapy With or Without Peripheral Stem Cell Transplantation in Treating Patients… | Phase 3 | terminated | May 26, 2004 | Gynecologic Oncology Group | not stated | Not stated |
| NCT00002976 | Estrogen Replacement Therapy in Treating Women With Early-Stage Endometrial Cancer | Phase 3 | terminated | Jan 27, 2003 | Gynecologic Oncology Group | not stated | Not stated |
| NCT00003386 | Vaccine Therapy in Treating Patients With Stage III or Stage IV Ovarian Epithelial Cancer | Phase 2 | terminated | Apr 23, 2004 | Gynecologic Oncology Group | not stated | Not stated |
| NCT00003624 | Amifostine in Treating Women With Ovarian, Peritoneal, Cervical, Fallopian Tube, Uterine,… | Phase 2 | terminated | Jun 16, 2004 | Gynecologic Oncology Group | not stated | Not stated |
| NCT00004037 | Docetaxel in Treating Patients With Recurrent or Refractory Ovarian or Primary Peritoneal… | Phase 2 | terminated | Jun 25, 2003 | Gynecologic Oncology Group | not stated | Not stated |
| NCT00006224 | Gemcitabine in Treating Patients With Persistent or Recurrent Cancer of the Cervix | Phase 2 | terminated | Nov 11, 2003 | Gynecologic Oncology Group | not stated | Not stated |
| NCT00006482 | Gemcitabine and Cisplatin in Treating Patients With Refractory or Recurrent Cancer of the… | Phase 2 | terminated | Oct 8, 2003 | Gynecologic Oncology Group | not stated | Not stated |
| NCT00006812 | Capecitabine in Treating Patients With Recurrent Ovarian Epithelial or Primary Peritoneal… | Phase 2 | terminated | Mar 17, 2004 | Gynecologic Oncology Group | not stated | Not stated |
| NCT00016341 | Combination Chemotherapy Compared With Hormone Therapy in Treating Patients With… | Phase 3 | terminated | Sep 9, 2003 | Gynecologic Oncology Group | not stated | Not stated |
| NCT00023907 | Paclitaxel in Treating Patients With Ovarian Epithelial Cancer or Primary Peritoneal… | Phase 2 | terminated | Jul 9, 2003 | Gynecologic Oncology Group | not stated | Not stated |
| NCT00030472 | Liposomal Doxorubicin in Treating Patients With Persistent or Recurrent Cancer of the… | Phase 2 | terminated | Jan 27, 2003 | Gynecologic Oncology Group | not stated | Not stated |
| NCT00054067 | Chemotherapy and Radiation Therapy With or Without Surgery in Treating Patients With… | Phase 3 | terminated | Feb 6, 2003 | Gynecologic Oncology Group | not stated | Not stated |
| NCT00258466 | Radiation Therapy in Treating Patients With Stage I, Stage II, or Stage III Prostate… | Phase 3 | withdrawn | Nov 24, 2005 | Barbara Ann Karmanos Cancer Institute | not stated | Not stated |
| NCT01616186 | Everolimus/Sorafenib or Sunitinib in Patients With Metastatic Renal Cell Carcinoma (RCC) | Phase 2 | withdrawn | Jun 11, 2012 | Andrea Harzstark | not stated | Not stated |
| NCT00010127 | Vaccine Therapy in Treating Patients With Metastatic Prostate Cancer | Phase 1 | terminated | Jul 30, 2003 | Duke University | not stated | Not stated |
| NCT00332280 | Study to Evaluate the Clinical Benefit Response in Cancer Patients With Advanced Disease… | Phase 2 / Phase 3 | terminated | Jun 1, 2006 | Auron Healthcare GmbH | Lack of efficacy. Stopped at first interim evaluation point | Efficacy / futility |
Stop reasons are registrant-reported free text and are displayed verbatim (truncated; hover for the full text). Categories come from explicit keyword rules and are never inferred from the study design, sponsor or outcome; a study that stopped for several reasons is filed under the first rule that matched. A TERMINATED status does not imply a negative result.
Data updated 23 days agoSource updated Jul 10, 2013source: clinicaltrials