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Clinical trials · failure tracking
Oncology studies whose overall status is TERMINATED, WITHDRAWN or SUSPENDED on ClinicalTrials.gov, with the stop reason exactly as the registrant posted it. A category is attached only when an explicit keyword rule matches the text; CancerIndex never infers why a study stopped.
826 stopped studies mapped to Malignant Female Reproductive System Neoplasm and descendants · 86% state a reason
Over the 826 studies matching the cancer, status and year filters (the category filter does not change this chart). Each study is counted once, in the first matching category; greyed bars are studies whose text matched no rule or was empty.
Computedrules ci-stop-reasons-v1 · keyword matching only
A category is assigned when one of its keywords appears in the posted text (case-insensitive, whole words). Rules are tested in this order and the first match wins; every match is kept in the API (reasonMatches).
| NCT | Title | Phase | Status | First posted | Lead sponsor | Why stopped (as posted) | Category |
|---|---|---|---|---|---|---|---|
| NCT01363466 | Evaluation of Hysterectomy After Chemoradiation Therapy for Stage IB2/II Cervical Cancer | Phase 3 | terminated | Jun 1, 2011 | UNICANCER | low recruitment | Enrollment / accrual |
| NCT00496067 | Uterine Artery Occlusion for Fibroid Related Bleeding | N/A | terminated | Jul 4, 2007 | Ethicon, Inc. | Data required further pilot work to be undertaken. | Other (stated, no rule matched) |
| NCT00629993 | Dissemination of Cervical Cancer Screening to Primary Care Physicians in Underserved… | Phase 4 | terminated | Mar 6, 2008 | Columbia University | Principal Investigator left the institution | Investigator |
| NCT01140555 | A Pilot Study to Determine Optimal Procedure Steps to Obtain and Maintain Uterine Artery… | N/A | terminated | Jun 9, 2010 | Ethicon, Inc. | Further internal evaluation of the device was required. | Other (stated, no rule matched) |
| NCT00531778 | NYU Ovarian Cancer Early Detection Program Blood and Genetics | — | terminated | Sep 19, 2007 | NYU Langone Health | insufficient funding and resource | Funding |
| NCT00082212 | A Study in Patients With Persistent or Recurrent Epithelial Ovarian or Primary Peritoneal… | Phase 2 | terminated | May 5, 2004 | Eli Lilly and Company | Due to lack of sufficient efficacy. | Efficacy / futility |
| NCT00277290 | Study of XL999 in Patients With Previously Treated Ovarian Cancer | Phase 2 | terminated | Jan 16, 2006 | Symphony Evolution, Inc. | Study was terminated due to cardiac toxicities in the subjects | Safety / toxicity |
| NCT01000896 | Study to Assess Safety and Tolerability of AZD0530 in Combination With Carboplatin and… | Phase 1 | withdrawn | Oct 23, 2009 | AstraZeneca | AstraZeneca has discontinued the development of AZD0530. No new AstraZeneca-sponsored clinical… | Other (stated, no rule matched) |
| NCT00317434 | Maximum Tolerated Dose of Lapatinib When Given With Carboplatin for Recurrent Ovarian… | Phase 1 | terminated | Apr 24, 2006 | University of Alabama at Birmingham | Due to unacceptable non-dose limiting toxicities, excessive treatment delays and limited clinical… | Safety / toxicity |
| NCT00161226 | A Randomized, Controlled, Comparative Study of a Levonorgestrel Intrauterine System for… | — | terminated | Sep 12, 2005 | University of Medicine and Dentistry of New Jersey | Principal investigator left institution | Investigator |
| NCT00610792 | Phase 2 Study of Twice Weekly VELCADE and CAELYX in Patients With Ovarian Cancer Failing… | Phase 2 | withdrawn | Feb 8, 2008 | Millennium Pharmaceuticals, Inc. | Study never submitted to IND. Study is being sponsored by Johnson and Johnson in the EU only. | Other (stated, no rule matched) |
| NCT00921635 | A Study to Evaluate the Impact of Maintaining Hemoglobin Levels in Anemic Patients With…(HOSTT) | Phase 3 | suspended | Jun 16, 2009 | Tri-Service General Hospital (TSGH) | not stated | Not stated |
| NCT00584207 | Radiofrequency Ablation of Uterine Fibroids | Early Phase 1 | terminated | Jan 2, 2008 | University of California, Davis | Unsufficient referrals for recruitment | Enrollment / accrual |
| NCT00753480 | A Study of D4064A Administered to Patients With Recurrent or Persistent Epithelial… | Phase 1 | suspended | Sep 16, 2008 | Genentech, Inc. | not stated | Not stated |
| NCT00451945 | New Indications for Ultrasound in the Staging of Cervical Cancer | N/A | withdrawn | Mar 26, 2007 | Rigshospitalet, Denmark | not stated | Not stated |
| NCT00050375 | Clinical Trial for Ovarian Cancer (OvaRex®) | Phase 3 | terminated | Dec 6, 2002 | Unither Pharmaceuticals | Study closed by sponser | Other (stated, no rule matched) |
| NCT00086632 | Study of Ovarex® (Oregovomab) MAb With Front-Line Chemotherapy for Ovarian Cancer… | Phase 2 | terminated | Jul 9, 2004 | Unither Pharmaceuticals | closed by sponser | Other (stated, no rule matched) |
| NCT00047632 | Safety and Efficacy of Interferon Gamma-1b Plus Chemotherapy for Ovarian and Peritoneal… | Phase 3 | terminated | Oct 11, 2002 | InterMune | futility | Efficacy / futility |
| NCT00189579 | Addition of Herceptin to a Carboplatin-Paclitaxel Regimen in Patients With Ovarian Cancer | Phase 2 | terminated | Sep 19, 2005 | ARCAGY/ GINECO GROUP | not stated | Not stated |
| NCT00106262 | Study of Velcade and Irinotecan in Advanced Cervical, Vulvar, or Vaginal Cancer | Phase 2 | terminated | Mar 22, 2005 | Women and Infants Hospital of Rhode Island | Lack of accrual | Enrollment / accrual |
| NCT00287482 | Essiac (ESIAK) Versus Placebo to Improve Quality of Life in Transition in Women With… | N/A | terminated | Feb 6, 2006 | Women and Infants Hospital of Rhode Island | not stated | Not stated |
| NCT00055432 | Gemzar (Gemcitabine) and Alimta (Pemetrexed) in the Treatment of Patients With Recurrent… | Phase 2 | terminated | Mar 4, 2003 | Eli Lilly and Company | not stated | Not stated |
| NCT00194935 | Weekly Topotecan Therapy in Patients With Ovarian Cancer | Phase 2 | terminated | Sep 19, 2005 | Weill Medical College of Cornell University | not stated | Not stated |
| NCT00220532 | Folate and Protection Against Cervical Cancer | Phase 1 / Phase 2 | terminated | Sep 22, 2005 | Sheffield Teaching Hospitals NHS Foundation Trust | not stated | Not stated |
| NCT00179725 | Phase I/II Open-Label, Dose Escalation Study To Determine The Maximum Tolerated Dose And… | Phase 1 / Phase 2 | terminated | Sep 16, 2005 | Celgene Corporation | not stated | Not stated |
| NCT00189371 | Reinduction Chemotherapy Containing Carboplatin and Paclitaxel With or Without Epoetin… | Phase 3 | terminated | Sep 19, 2005 | AGO Study Group | not stated | Not stated |
Stop reasons are registrant-reported free text and are displayed verbatim (truncated; hover for the full text). Categories come from explicit keyword rules and are never inferred from the study design, sponsor or outcome; a study that stopped for several reasons is filed under the first rule that matched. A TERMINATED status does not imply a negative result.
Data updated 22 days agoSource updated Jun 1, 2011source: clinicaltrials