Clinical trial · Interventional
A Study to Evaluate the Impact of Maintaining Hemoglobin Levels in Anemic Patients With Carcinoma of the Cervix
A Phase III Study to Evaluate the Impact of Maintaining Haemoglobin Levels Above 120g/L Verses Above 100g/L in Anaemic Patients With Carcinoma of the Cervix Receiving Concurrent Cisplatin and Radiation Therapy
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The purpose of this study is to assess the feasibility, safety and short term effects on health related quality of life, of maintaining hemoglobin from 120 to 130 g/L versus from 100 to 110 g/L, with red cell concentrate (RCC) transfusion, in women having chemo-radiation for cancer of the cervix.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Anemia | — | UNRESOLVED | — |
| Cervical Cancer | Malignant Cervical Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Blood transfusion | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Maintain hemoglobin level above 120 g/L
- description
- Hemoglobin level from 120 g/L to 130 g/L
- interventionNames
- Procedure: Blood transfusion
- type
- ACTIVE_COMPARATOR
- label
- Maintain hemoglobin level above 100 g/L
- description
- Hemoglobin level from 100 g/L to 110 g/L
- interventionNames
- Procedure: Blood transfusion
Primary outcomes (1)
- measure
- The impact of maintaining hemoglobin levels above 120 g/L versus above 100 g/L
- timeFrame
- 5 years
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Previously untreated cervix cancer * FIGO stage IB2, II, IIIB, IVA * Suitable for treatment with radical intent using concurrent cisplatin and pelvic radiation Exclusion Criteria: * Hemoglobin level above 125g/L * Lower one-third vaginal involvement * Para-aortic lymphadenopathy
References
Publications (0)
Data not yet available