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Clinical trials · failure tracking
Oncology studies whose overall status is TERMINATED, WITHDRAWN or SUSPENDED on ClinicalTrials.gov, with the stop reason exactly as the registrant posted it. A category is attached only when an explicit keyword rule matches the text; CancerIndex never infers why a study stopped.
826 stopped studies mapped to Malignant Female Reproductive System Neoplasm and descendants · 86% state a reason
Over the 826 studies matching the cancer, status and year filters (the category filter does not change this chart). Each study is counted once, in the first matching category; greyed bars are studies whose text matched no rule or was empty.
Computedrules ci-stop-reasons-v1 · keyword matching only
A category is assigned when one of its keywords appears in the posted text (case-insensitive, whole words). Rules are tested in this order and the first match wins; every match is kept in the API (reasonMatches).
| NCT | Title | Phase | Status | First posted | Lead sponsor | Why stopped (as posted) | Category |
|---|---|---|---|---|---|---|---|
| NCT01175967 | Use of Palliative Performance and Symptom Distress Scales in Older Patients With Advanced… | — | terminated | Aug 5, 2010 | UNC Lineberger Comprehensive Cancer Center | Unable to meet accrual due to changing practice patters | Enrollment / accrual |
| NCT00093678 | Celecoxib in Managing Pain, Weight Loss, and Weakness in Patients With Advanced Cancer | N/A | withdrawn | Oct 8, 2004 | Eastern Cooperative Oncology Group | not stated | Not stated |
| NCT00758732 | Docetaxel/Carboplatin Versus Docetaxel/Caelyx in Pretreated Patients With Ovarian… | Phase 2 | terminated | Sep 25, 2008 | Hellenic Oncology Research Group | Poor accrual | Enrollment / accrual |
| NCT01296035 | Panitumumab and Gemcitabine in Relapsed Ovarian Cancer(PanGem) | Phase 2 | terminated | Feb 15, 2011 | Women and Infants Hospital of Rhode Island | Newer technologies available; poor accrual to study. | Enrollment / accrual |
| NCT00471120 | Feasibility Study: Accuracy of Biomarker in Detection of Endometrial Cancer | N/A | terminated | May 9, 2007 | Dick Domanik | Study terminated due to protocol deficiencies. | Other (stated, no rule matched) |
| NCT01744821 | Vitamin D for Women at Increased Risk of Developing Ovarian, Fallopian, or Primary… | N/A | terminated | Dec 7, 2012 | Northwestern University | Inability to recruit study subjects | Enrollment / accrual |
| NCT00233727 | Screen and Treat for Cervical Cancer Prevention(SAT) | Phase 3 | terminated | Oct 6, 2005 | Columbia University | PI left University | Investigator |
| NCT01175772 | Maintenance Treatment for Ovarian Carcinoma in Remission by an Antiangiogenic Treatment… | Phase 2 | terminated | Aug 5, 2010 | HaEmek Medical Center, Israel | Due to change in the national policy of medications | Other (stated, no rule matched) |
| NCT00365443 | Broad Spectrum HPV Vaccine Tolerability, Immunogenicity, and Efficacy Study (V502-003) | Phase 2 | withdrawn | Aug 17, 2006 | Merck Sharp & Dohme LLC | not stated | Not stated |
| NCT00323726 | Trends in Incidence and Survivals for Ovarian Germ Cell Tumors: A 27-Year… | — | withdrawn | May 9, 2006 | New Mexico Cancer Research Alliance | The study was limited to IRB Exempt chart review; not an applicable trial. | Other (stated, no rule matched) |
| NCT01880996 | Tai-chi / Qi-gong in Patients With Patients With Gynecological Malignancies | Phase 1 / Phase 2 | withdrawn | Jun 19, 2013 | Sheba Medical Center | The deparment failed to detect patients that were willing to participate in this study | Other (stated, no rule matched) |
| NCT00053235 | Research Study in Patients With Advanced Ovarian Epithelial Cancer | — | withdrawn | Jan 28, 2003 | Gynecologic Oncology Group | not stated | Not stated |
| NCT01200797 | SJG-136 in Treating Patients With Epithelial Ovarian, Primary Peritoneal, or Fallopian… | Phase 2 | terminated | Sep 14, 2010 | National Cancer Institute (NCI) | Slow accrual was the reason for study termination. | Enrollment / accrual |
| NCT01198535 | Phase I Study of Cetuximab With RO4929097 in Metastatic Colorectal Cancer | Phase 1 | terminated | Sep 10, 2010 | National Cancer Institute (NCI) | not stated | Not stated |
| NCT01401829 | Psychosocial Benefits of Exercise in Endometrial Cancer Survivors | Phase 1 | terminated | Jul 25, 2011 | University of Alabama at Birmingham | Terminated due to lack of funding required to continue the study. | Funding |
| NCT02235324 | Ziv-Aflibercept Followed by Ziv-Aflibercept, Fluorouracil, and Leucovorin Calcium in… | Phase 2 | withdrawn | Sep 9, 2014 | University of Southern California | Lack of funding | Funding |
| NCT00003880 | Paclitaxel Plus Carboplatin With or Without SCH-58500 in Treating Patients With Newly… | Phase 2 / Phase 3 | terminated | Apr 23, 2004 | Merck Sharp & Dohme LLC | not stated | Not stated |
| NCT02095847 | High-Resolution Microendoscopy to Guide Hysteroscopic Tumor Resection | Phase 2 | withdrawn | Mar 26, 2014 | M.D. Anderson Cancer Center | not stated | Not stated |
| NCT01226290 | Fibroid Ablation Study(FAST-EU) | N/A | terminated | Oct 22, 2010 | Gynesonics | Investigational device changes; adequate enrollment achieved | Enrollment / accrual |
| NCT01732432 | Endometriosis and Frequency of Endometriosis-associated Ovarian Carcinomas (EAOC)(EAOC) | — | withdrawn | Nov 22, 2012 | University Hospital, Basel, Switzerland | not stated | Not stated |
| NCT00736216 | Knowledge and Perceptions About Human Papillomavirus and Cervical Cancer Risk Among Young… | — | withdrawn | Aug 15, 2008 | Case Comprehensive Cancer Center | PI left the institution | Investigator |
| NCT00659399 | Feasibility Study of Short Term Fondaparinux (Arixtra) in Chemotherapy-Pretreated Ovarian… | Phase 1 | withdrawn | Apr 16, 2008 | NYU Langone Health | Low accrual | Enrollment / accrual |
| NCT01017809 | Prolonged Emend in a Study (NYU 03-67) of Oxaliplatin and Topotecan in Previously Treated… | N/A | withdrawn | Nov 23, 2009 | NYU Langone Health | NYU 03-67 reached accrual prior to this study opening. | Enrollment / accrual |
| NCT01539187 | Fibroid Ablation Study - Large Fibroids(FAST-L) | N/A | terminated | Feb 27, 2012 | Gynesonics | Investigational device changes | Other (stated, no rule matched) |
| NCT01998854 | Observational Prospective Study on Patients With Symptomatic Uterine Fibroids Treated… | — | terminated | Dec 2, 2013 | Gynesonics | Investigational device changes | Other (stated, no rule matched) |
| NCT00442598 | Safety and Efficacy Study of Glufosfamide in Ovarian Cancer | Phase 2 | terminated | Mar 2, 2007 | Eleison Pharmaceuticals LLC. | not stated | Not stated |
| NCT00023634 | S0114 Vaccine Therapy in Treating Patients With Gastric, Prostate, or Ovarian Cancer | Phase 1 | terminated | Jan 27, 2003 | SWOG Cancer Research Network | lack of accrual | Enrollment / accrual |
| NCT02312804 | Ph Ib/BGJ398/Cervix and Other Solid Tumors | Phase 1 | withdrawn | Dec 9, 2014 | The University of Texas Health Science Center at San Antonio | Drug not available. | Other (stated, no rule matched) |
| NCT00539968 | A Study to Evaluate the Safety, Tolerability, and Activity of Lonafarnib and Docetaxel… | Phase 1 / Phase 2 | terminated | Oct 5, 2007 | Merck Sharp & Dohme LLC | not stated | Not stated |
| NCT00312650 | Doxil and Gemcitabine in Recurrent Ovarian Cancer | Phase 2 | terminated | Apr 10, 2006 | Women and Infants Hospital of Rhode Island | not stated | Not stated |
| NCT01492920 | Acetyl-L-Carnitine Hydrochloride in Preventing Peripheral Neuropathy in Patients With… | Phase 3 | withdrawn | Dec 15, 2011 | Gynecologic Oncology Group | Withdrawn | Other (stated, no rule matched) |
| NCT01927393 | Palliative Care in Improving Quality of Life and Symptoms in Patients With Stage III-IV… | N/A | withdrawn | Aug 22, 2013 | City of Hope Medical Center | Study was not funded | Funding |
| NCT01777230 | The Value of Preoperative Sentinel Lymph Node Mapping by Pelvic MR Lymphangiography and… | — | withdrawn | Jan 28, 2013 | UMC Utrecht | Unable to get required research materials | Other (stated, no rule matched) |
| NCT01747239 | Cabazitaxel in Platinum Refractory Ovarian Cancer | Phase 2 | terminated | Dec 11, 2012 | Vejle Hospital | Too low inclusion rate. Only 4 patients included over 16 months | Other (stated, no rule matched) |
| NCT00787488 | Pilot Study of IV and IP Chemotherapy Plus Abdominal Hyperthermia for Ovarian Ca | N/A | withdrawn | Nov 7, 2008 | Mark Dewhirst | Study not funded | Funding |
| NCT01149434 | Study of JI-101 in Patients With Advanced Low Grade Endocrine Tumors, Ovarian Cancers or… | Phase 1 / Phase 2 | terminated | Jun 23, 2010 | University of Utah | Lack of drug efficacy | Efficacy / futility |
| NCT01095367 | Seprafilm™ for the Prevention of Intraperitoneal Adhesions and Improved Delivery of… | N/A | terminated | Mar 30, 2010 | University of British Columbia | due to company changes and lack of funding-unlikely to have sufficient numbers to analyze… | Funding |
| NCT02017678 | Phase 2 Study of JX-594 in Patients With Peritoneal Carcinomatosis of Ovarian Cancer… | Phase 2 | withdrawn | Dec 23, 2013 | Andrea McCart | not stated | Not stated |
| NCT01943058 | Megestrol Acetate or Levonorgestrel-Releasing Intrauterine System in Treating Patients… | Phase 2 | withdrawn | Sep 16, 2013 | University of Southern California | Lack of funding | Funding |
| NCT01786226 | Mifepristone to Treat Uterine Fibroids | Phase 2 / Phase 3 | terminated | Feb 7, 2013 | Mediterranea Medica S. L. | not stated | Not stated |
| NCT00958893 | An Extension Study Evaluating Safety and Efficacy of Proellex® In Women Who Have… | Phase 2 | terminated | Aug 13, 2009 | Repros Therapeutics Inc. | Repros stopped the study for safety and FDA put the study on hold for safety. | Safety / toxicity |
| NCT00470067 | Doxorubicin Hydrochloride Liposome and Carboplatin in Treating Patients With Recurrent,… | Phase 2 | terminated | May 7, 2007 | Roswell Park Cancer Institute | Due to low accrual | Enrollment / accrual |
| NCT00536523 | Effect of Serotonin Level on Constipation Caused by Chemotherapy in Patients With… | — | terminated | Sep 28, 2007 | University of Minnesota | Funding unavailable | Funding |
| NCT01284075 | The Effect of Guided Imagery and Music Therapy on Post-Operative Recovery After… | N/A | terminated | Jan 26, 2011 | University of Minnesota | Low accrual | Enrollment / accrual |
| NCT00683917 | Pharmacokinetics, Safety and Efficacy Study of Proellex in Pre-menopausal Women With… | Phase 2 | terminated | May 26, 2008 | Repros Therapeutics Inc. | Repros stopped the study for safety and FDA put the study on hold for safety. | Safety / toxicity |
| NCT00702702 | Safety and Efficacy of Proellex in Pre-menopausal Anemic Women With Symptomatic Uterine… | Phase 3 | terminated | Jun 20, 2008 | Repros Therapeutics Inc. | Repros stopped study for safety and FDA put study on hold because of safety. | Safety / toxicity |
| NCT00735553 | Evaluating the Safety and Efficacy of Proellex® (CDB-4124) in Premenopausal Women With… | Phase 3 | terminated | Aug 15, 2008 | Repros Therapeutics Inc. | Repros stopped the study for safety and FDA put the study on hold for safety. | Safety / toxicity |
| NCT00737282 | Multicenter Study Evaluating the Safety of Proellex® in Premenopausal Women With Uterine… | Phase 3 | terminated | Aug 18, 2008 | Repros Therapeutics Inc. | Repros stopped study for safety and FDA put study on hold. | Safety / toxicity |
| NCT00785356 | Safety and Efficacy of Proellex in Pre-Menopausal Anemic Women With Symptomatic Uterine… | Phase 3 | terminated | Nov 5, 2008 | Repros Therapeutics Inc. | Repros stopped the study for safety and FDA put the study on hold for safety. | Safety / toxicity |
| NCT00853567 | Evaluating the Safety and Efficacy of Proellex® in Premenopausal Women With Symptomatic… | Phase 3 | terminated | Mar 2, 2009 | Repros Therapeutics Inc. | Repros stopped the study for safety and FDA put the study on hold for safety. | Safety / toxicity |
Stop reasons are registrant-reported free text and are displayed verbatim (truncated; hover for the full text). Categories come from explicit keyword rules and are never inferred from the study design, sponsor or outcome; a study that stopped for several reasons is filed under the first rule that matched. A TERMINATED status does not imply a negative result.
Data updated 23 days agoSource updated Oct 12, 2015source: clinicaltrials