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Clinical trials · failure tracking
Oncology studies whose overall status is TERMINATED, WITHDRAWN or SUSPENDED on ClinicalTrials.gov, with the stop reason exactly as the registrant posted it. A category is attached only when an explicit keyword rule matches the text; CancerIndex never infers why a study stopped.
72 stopped studies mapped to Malignant Eye Neoplasm and descendants · 86% state a reason
Over the 72 studies matching the cancer, status and year filters (the category filter does not change this chart). Each study is counted once, in the first matching category; greyed bars are studies whose text matched no rule or was empty.
Computedrules ci-stop-reasons-v1 · keyword matching only
A category is assigned when one of its keywords appears in the posted text (case-insensitive, whole words). Rules are tested in this order and the first match wins; every match is kept in the API (reasonMatches).
| NCT | Title | Phase | Status | First posted | Lead sponsor | Why stopped (as posted) | Category |
|---|---|---|---|---|---|---|---|
| NCT01857752 | Phase II Study Temozolomide for Retinoblastoma Metastatic to the Central Nervous System… | Phase 2 | terminated | May 20, 2013 | Stanford University | accrual | Enrollment / accrual |
| NCT02655432 | Performance of a Photoscreener for Vision Screening in a Haitian Pediatric Population(POPH) | — | withdrawn | Jan 14, 2016 | Université de Montréal | waiting for ethic board approval | Other (stated, no rule matched) |
| NCT02281279 | Rituximab, Romidepsin, and Lenalidomide in Treating Patients With Recurrent or Refractory… | Phase 1 / Phase 2 | withdrawn | Nov 3, 2014 | Mayo Clinic | not stated | Not stated |
| NCT01393769 | Intra-arterial Chemotherapy With Melphalan for the Treatment of Retinoblastoma (RTB) in… | Phase 2 | terminated | Jul 13, 2011 | Hospital Sant Joan de Deu | Only 5 subjects could be enrolled. Sample of 25 pat. not be achieved (rare disease). | Enrollment / accrual |
| NCT01652014 | Single or Double Donor Umbilical Cord Blood Transplant in Treating Patients With… | Phase 2 | withdrawn | Jul 27, 2012 | University of Medicine and Dentistry of New Jersey | Funding unavailable | Funding |
| NCT01730157 | Radioembolization and Ipilimumab in Treating Patients With Uveal Melanoma With Liver… | Early Phase 1 | terminated | Nov 21, 2012 | Case Comprehensive Cancer Center | Research Cancelled | Other (stated, no rule matched) |
| NCT00003273 | Chemotherapy Followed by Peripheral Stem Cell Transplantation in Treating Children With… | Phase 2 | withdrawn | Jan 27, 2003 | NYU Langone Health | not stated | Not stated |
| NCT01558960 | Intravitreal Injections of Melphalan for Retinoblastoma | N/A | terminated | Mar 20, 2012 | Hadassah Medical Organization | Sufficient findings to draw conclusions | Other (stated, no rule matched) |
| NCT02109224 | Ibrutinib in Treating Relapsed or Refractory B-Cell Non-Hodgkin Lymphoma in Patients With… | Phase 1 | terminated | Apr 9, 2014 | National Cancer Institute (NCI) | Inadequate accrual rate | Enrollment / accrual |
| NCT01769911 | Genetically Modified Peripheral Blood Stem Cell Transplant in Treating Patients With… | N/A | withdrawn | Jan 17, 2013 | Fred Hutchinson Cancer Center | not stated | Not stated |
| NCT00432445 | Proton Beam Radiation Therapy for Intraocular and Periocular Retinoblastoma | Phase 2 | terminated | Feb 7, 2007 | M.D. Anderson Cancer Center | Low accrual. | Enrollment / accrual |
| NCT00002947 | Indium In 111 Pentetreotide in Treating Patients With Refractory Cancer | Phase 1 | terminated | Mar 26, 2004 | Yale University | not stated | Not stated |
| NCT00089076 | MDX-010 in Treating Patients With Recurrent or Refractory Lymphoma | Phase 1 / Phase 2 | terminated | Aug 5, 2004 | National Cancer Institute (NCI) | not stated | Not stated |
| NCT00005841 | Vaccine Therapy in Treating Patients With Stage III or Stage IV Melanoma | Phase 1 | terminated | May 26, 2004 | University of Southern California | Toxicity/Side Effects | Safety / toxicity |
| NCT00933985 | Obatoclax Mesylate, Vincristine Sulfate, Doxorubicin Hydrochloride, and Dexrazoxane… | Phase 1 | terminated | Jul 8, 2009 | National Cancer Institute (NCI) | not stated | Not stated |
| NCT00101205 | Oxaliplatin, Ifosfamide and Etoposide in Treating Young Patients With Recurrent or… | Phase 1 | terminated | Jan 10, 2005 | National Cancer Institute (NCI) | not stated | Not stated |
| NCT00621439 | Investigative Trial of Interferon Alpha-2b To Shrink Cancer of the Eye | N/A | withdrawn | Feb 22, 2008 | Emory University | no funding- study never began | Funding |
| NCT00354185 | PXD101 and 17-N-Allylamino-17-Demethoxygeldanamycin in Treating Patients With Metastatic… | Phase 1 | terminated | Jul 20, 2006 | National Cancer Institute (NCI) | not stated | Not stated |
| NCT00036816 | Vaccine Therapy in Treating Patients With Melanoma of the Eye | Phase 3 | terminated | Jan 27, 2003 | European Organisation for Research and Treatment of Cancer - EORTC | low accrual | Enrollment / accrual |
| NCT00110123 | Intravenous or Hepatic Arterial Infusion of Fotemustine in Treating Patients With… | Phase 3 | terminated | May 4, 2005 | European Organisation for Research and Treatment of Cancer - EORTC | low accrual | Enrollment / accrual |
| NCT01151748 | Intra-arterial Chemotherapy for Advanced Intraocular Retinoblastoma | Phase 2 | withdrawn | Jun 28, 2010 | Stanford University | Study abandoned; Could not obtain final SRC approval due to IND disagreements | Other (stated, no rule matched) |
| NCT01116154 | Vorinostat and Lenalidomide in Treating Patients With Relapsed or Refractory Hodgkin… | Phase 1 | terminated | May 4, 2010 | City of Hope Medical Center | Sponsor withdrew support for the study | Other (stated, no rule matched) |
Stop reasons are registrant-reported free text and are displayed verbatim (truncated; hover for the full text). Categories come from explicit keyword rules and are never inferred from the study design, sponsor or outcome; a study that stopped for several reasons is filed under the first rule that matched. A TERMINATED status does not imply a negative result.
Data updated 22 days agoSource updated Jan 30, 2017source: clinicaltrials