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Clinical trials · failure tracking
Oncology studies whose overall status is TERMINATED, WITHDRAWN or SUSPENDED on ClinicalTrials.gov, with the stop reason exactly as the registrant posted it. A category is attached only when an explicit keyword rule matches the text; CancerIndex never infers why a study stopped.
127 stopped studies mapped to Malignant Endometrial Neoplasm and descendants · 87% state a reason
Over the 127 studies matching the cancer, status and year filters (the category filter does not change this chart). Each study is counted once, in the first matching category; greyed bars are studies whose text matched no rule or was empty.
Computed
A category is assigned when one of its keywords appears in the posted text (case-insensitive, whole words). Rules are tested in this order and the first match wins; every match is kept in the API (reasonMatches).
| NCT | Title | Phase | Status | First posted | Lead sponsor | Why stopped (as posted) | Category |
|---|---|---|---|---|---|---|---|
| NCT02868892 | A Study of Pemetrexed in Recurrent Cervical Adenocarcinomas | Phase 2 | terminated | Aug 16, 2016 | Western Regional Medical Center | departure of PI from institution and poor population for study participation | Other (stated, no rule matched) |
| NCT02589366 | Lymphoseek as Lymphoid Tissue Targeting Agent in Patients With Cancer of the Endometrium | Phase 1 | terminated | Oct 28, 2015 | University of California, San Diego | not stated | Not stated |
| NCT00003821 | Aminopterin in Treating Patients With Recurrent or Refractory Endometrial Cancer | Phase 2 | withdrawn | Aug 4, 2004 | Genzyme, a Sanofi Company | not stated | Not stated |
| NCT02765698 | Efficacy of PET/MRI in Detecting Metastatic Disease in Endometrial Cancer | — | terminated | May 9, 2016 | Mayo Clinic | not stated | Not stated |
| NCT00375804 | Racial Disparity in Endometrial Cancer | — | terminated | Sep 13, 2006 | University of Louisville | Funding and logistical difficuties resulted in the withdrawl of the study. | Funding |
| NCT00070317 | Lymph Node Mapping and Sentinel Lymph Node Identification in Patients With Stage IB1… | N/A | terminated | Oct 7, 2003 | Gynecologic Oncology Group | not stated | Not stated |
| NCT01641497 | Phase III Study Comparing 3D Conformal Radiotherapy and Conformal Radiotherapy IMRT to…(TOMOGYN) | N/A | terminated | Jul 16, 2012 | Centre Oscar Lambret | Recruitment difficulties | Enrollment / accrual |
| NCT01184053 | Trisenox® in Women With Metastatic Endometrial Cancer(NRR) | Phase 2 | terminated | Aug 18, 2010 | UNC Lineberger Comprehensive Cancer Center | Accrual was very low. No subject had been enrolled in a year. | Enrollment / accrual |
| NCT00883116 | A Study of Ixabepilone as Second-line Therapy for Locally Advanced, Recurrent, or…(IXAMPLE2) | Phase 3 | terminated | Apr 17, 2009 | R-Pharm | Interim analysis results showed that ixabepilone did not improve survival compared with control… | Efficacy / futility |
| NCT02042495 | Endometrial Cancer Biomarker Changes Following Exposure to Metformin | Phase 2 | withdrawn | Jan 23, 2014 | Jewish General Hospital | Did not obtain Health Canda approval for drug use in reasonable time and moved onward to new trial | Other (stated, no rule matched) |
| NCT00671606 | Hysteroscopic Lymphatic Mapping for Endometrial Cancer | Phase 2 | terminated | May 5, 2008 | M.D. Anderson Cancer Center | Slow accrual. | Enrollment / accrual |
| NCT02042885 | A Clinical Trial to Determine the Most Suitable Dose of OPB-111001 in Patients With… | Phase 1 / Phase 2 | terminated | Jan 23, 2014 | Otsuka Novel Products GmbH | not stated | Not stated |
| NCT00471120 | Feasibility Study: Accuracy of Biomarker in Detection of Endometrial Cancer | N/A | terminated | May 9, 2007 | Dick Domanik | Study terminated due to protocol deficiencies. | Other (stated, no rule matched) |
| NCT01401829 | Psychosocial Benefits of Exercise in Endometrial Cancer Survivors | Phase 1 | terminated | Jul 25, 2011 | University of Alabama at Birmingham | Terminated due to lack of funding required to continue the study. | Funding |
| NCT01943058 | Megestrol Acetate or Levonorgestrel-Releasing Intrauterine System in Treating Patients… | Phase 2 | withdrawn | Sep 16, 2013 | University of Southern California | Lack of funding | Funding |
| NCT00470067 | Doxorubicin Hydrochloride Liposome and Carboplatin in Treating Patients With Recurrent,… | Phase 2 | terminated | May 7, 2007 | Roswell Park Cancer Institute | Due to low accrual | Enrollment / accrual |
| NCT01550380 | BKM120 in Advanced, Metastatic, or Recurrent Endometrial Cancers(BKM120) | Phase 2 | withdrawn | Mar 12, 2012 | University of Utah | not stated | Not stated |
| NCT01498237 | Photoacoustic Endoscopy in Endometrial Cancer | Early Phase 1 | withdrawn | Dec 23, 2011 | Washington University School of Medicine | Need to obtain IDE prior to commencement of study | Other (stated, no rule matched) |
| NCT00566644 | Intrauterine Levonorgestrel and Observation or Observation Alone in Preventing Atypical… | Phase 3 | terminated | Dec 3, 2007 | St George's, University of London | Withdrawn due to poor accrual | Enrollment / accrual |
| NCT00003179 | Surgery Plus Medroxyprogesterone in Preventing Endometrial Cancer | Phase 2 | terminated | Jan 27, 2003 | Gynecologic Oncology Group | not stated | Not stated |
| NCT00002976 | Estrogen Replacement Therapy in Treating Women With Early-Stage Endometrial Cancer | Phase 3 | terminated | Jan 27, 2003 | Gynecologic Oncology Group | not stated | Not stated |
| NCT00003624 | Amifostine in Treating Women With Ovarian, Peritoneal, Cervical, Fallopian Tube, Uterine,… | Phase 2 | terminated | Jun 16, 2004 | Gynecologic Oncology Group | not stated | Not stated |
| NCT00016341 | Combination Chemotherapy Compared With Hormone Therapy in Treating Patients With… | Phase 3 | terminated | Sep 9, 2003 | Gynecologic Oncology Group | not stated | Not stated |
| NCT00669422 | ChemoFx® PRO - A Post-Market Data Collection Study | — | terminated | Apr 30, 2008 | Precision Therapeutics | not stated | Not stated |
| NCT01290406 | BEZ235 Trial in Patients With Advanced Endometrial Carcinoma | Phase 2 | withdrawn | Feb 7, 2011 | Novartis Pharmaceuticals | not stated | Not stated |
| NCT00118300 | Capecitabine and Radiation Therapy in Treating Patients With Locally Advanced Cervical… | Phase 1 | withdrawn | Jul 11, 2005 | Case Comprehensive Cancer Center | Competing studies | Other (stated, no rule matched) |
| NCT00161226 | A Randomized, Controlled, Comparative Study of a Levonorgestrel Intrauterine System for… | — | terminated | Sep 12, 2005 | University of Medicine and Dentistry of New Jersey | Principal investigator left institution | Investigator |
Stop reasons are registrant-reported free text and are displayed verbatim (truncated; hover for the full text). Categories come from explicit keyword rules and are never inferred from the study design, sponsor or outcome; a study that stopped for several reasons is filed under the first rule that matched. A TERMINATED status does not imply a negative result.
Data updated 22 days agoSource updated Nov 2, 2018source: clinicaltrials