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Clinical trials · failure tracking
Oncology studies whose overall status is TERMINATED, WITHDRAWN or SUSPENDED on ClinicalTrials.gov, with the stop reason exactly as the registrant posted it. A category is attached only when an explicit keyword rule matches the text; CancerIndex never infers why a study stopped.
150 stopped studies mapped to Hodgkin Lymphoma and descendants · 86% state a reason
Over the 150 studies matching the cancer, status and year filters (the category filter does not change this chart). Each study is counted once, in the first matching category; greyed bars are studies whose text matched no rule or was empty.
Computed
A category is assigned when one of its keywords appears in the posted text (case-insensitive, whole words). Rules are tested in this order and the first match wins; every match is kept in the API (reasonMatches).
| NCT | Title | Phase | Status | First posted | Lead sponsor | Why stopped (as posted) | Category |
|---|---|---|---|---|---|---|---|
| NCT02408042 | Study of Pembrolizumab With Chemotherapy in Patients With Advanced Lymphoma (PembroHeme) | Phase 1 / Phase 2 | withdrawn | Apr 3, 2015 | Western Regional Medical Center | not stated | Not stated |
| NCT01220297 | Sirolimus & Mycophenolate Mofetil as GvHD Prophylaxis in Myeloablative, Matched Related… | Phase 2 | terminated | Oct 13, 2010 | Stanford University | Low accrual | Enrollment / accrual |
| NCT02200380 | A Safety and Tolerability Study of CDX-301 With or Without Plerixafor for Stem Cell… | Phase 2 | terminated | Jul 25, 2014 | Celldex Therapeutics | not stated | Not stated |
| NCT00698685 | Pentostatin and Alemtuzumab as a Preparative Regimen for Allogeneic Peripheral Blood Stem… | Phase 2 | terminated | Jun 17, 2008 | University of Arizona | Pentostatin/alemtuzumab regimen had greater risk of graft failure. | Other (stated, no rule matched) |
| NCT02473523 | Yoga to Alleviate Fatigue, Anxiety and Pain in Adolescents During Treatment for Lymphoma… | N/A | terminated | Jun 16, 2015 | St. Jude Children's Research Hospital | The principal investigator left the institution. | Investigator |
| NCT01032148 | Study of LBH589, A Deacetylase Inhibitor in Patients With Recurrent or Refractory Hodgkin… | Phase 1 | terminated | Dec 15, 2009 | Roswell Park Cancer Institute | lack of funding | Funding |
| NCT01555853 | Phase I/II Study of Abraxane in Recurrent and Refractory Lymphoma | Phase 1 | terminated | Mar 16, 2012 | Washington University School of Medicine | completed accrual to phase I but drug did not show activity, so halted before initiation of phase II | Enrollment / accrual |
| NCT01745354 | Immunostimulatory CpG SD-101 + RT in Recurrent/Progressive Lymphoma After Allogeneic… | Phase 1 | terminated | Dec 10, 2012 | Robert Lowsky | Accrual issues - Slow accrual | Enrollment / accrual |
| NCT01704742 | Prospective Study of Lymphoproliferative Diseases | — | withdrawn | Oct 11, 2012 | West Virginia University | Protocol not considered a clinical trial for registration purposes; no subjects enrolled to date… | Enrollment / accrual |
| NCT02115126 | Phase II Trial to Evaluate an EBV-derived Dendritic Cell Vaccine in Autologous Stem Cell… | Phase 2 | withdrawn | Apr 15, 2014 | David Rizzieri, MD | not stated | Not stated |
| NCT01699581 | Assessment of Impact Nutritional Program During Autologous Stem Cell Transplant | Phase 2 | terminated | Oct 3, 2012 | Greg Monohan | Research cancelled following interim analysis | Efficacy / futility |
| NCT01188915 | Personalised Program for Women Treated for Hodgkin Disease(PROPER) | N/A | terminated | Aug 26, 2010 | Institut Paoli-Calmettes | Sponsor decision | Sponsor / business decision |
| NCT00879528 | Consolidation PET-based and Donor-based After Salvage Therapy in Patients With HL in… | — | terminated | Apr 10, 2009 | Fondazione Italiana Linfomi - ETS | Failure of accrual achievement | Enrollment / accrual |
| NCT00112723 | Flavopiridol in Treating Patients With Relapsed or Refractory Lymphoma or Multiple Myeloma | Phase 1 / Phase 2 | terminated | Jun 3, 2005 | National Cancer Institute (NCI) | Administratively Complete | Other (stated, no rule matched) |
| NCT01652014 | Single or Double Donor Umbilical Cord Blood Transplant in Treating Patients With… | Phase 2 | withdrawn | Jul 27, 2012 | University of Medicine and Dentistry of New Jersey | Funding unavailable | Funding |
| NCT02080416 | Nelfinavir for the Treatment of Gammaherpesvirus-Related Tumors | Early Phase 1 | terminated | Mar 6, 2014 | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | Very slow accrual; terminated to allow resources to be utilized more effectively on other studies.… | Enrollment / accrual |
| NCT00578461 | T-Regulatory Cell Kinetics, Stem Cell Transplantation, REGKINE(REGKINE) | N/A | terminated | Dec 21, 2007 | Baylor College of Medicine | not stated | Not stated |
| NCT00578539 | T-Reg Cell Kinetics, Stem Cell Transplant, REGALE(REGALE) | N/A | terminated | Dec 21, 2007 | Baylor College of Medicine | not stated | Not stated |
| NCT00512980 | PVAG-14 Pilot for Intermediate Stages Hodgkin Lymphoma | Phase 2 | terminated | Aug 8, 2007 | University of Cologne | lower recruitment rates as expected | Enrollment / accrual |
| NCT01050946 | Hematopoietic Stem Cell Transplantation (HSCT) Using CD34 Selected Mismatched Related…(Haplo/Cord) | Phase 2 | terminated | Jan 18, 2010 | Medical College of Wisconsin | Only one patient was enrolled. Due to low accrual study was terminated | Enrollment / accrual |
| NCT02000986 | Dietary and Exercise Interventions in Preventing Cardiovascular Disease in Younger… | N/A | withdrawn | Dec 4, 2013 | Virginia Commonwealth University | Slow accrual | Enrollment / accrual |
| NCT01908387 | Phase 1 Study of CC-486 in Japanese Subjects With Hematological Neoplasms | Phase 1 | terminated | Jul 25, 2013 | Celgene Corporation | Due to Slow Accrual study was terminated. | Enrollment / accrual |
| NCT00358982 | Study of MGCD0103 (MG-0103) in Patients With Relapsed or Refractory Hodgkin's Lymphoma | Phase 2 | terminated | Aug 1, 2006 | Mirati Therapeutics Inc. | not stated | Not stated |
| NCT00543582 | MGCD0103 Administered in Combination With Azacitidine (Vidaza®) to Subjects With Relapsed… | Phase 2 | terminated | Oct 15, 2007 | Mirati Therapeutics Inc. | Celgene terminated its collaboration agreement with MethylGene for the development of MGCD0103. All… | Other (stated, no rule matched) |
| NCT00963495 | Study Evaluating the Tolerance and Biological Activity of Oral Clioquinol in Patients… | Phase 1 | terminated | Aug 21, 2009 | University Health Network, Toronto | not stated | Not stated |
| NCT01769911 | Genetically Modified Peripheral Blood Stem Cell Transplant in Treating Patients With… | N/A | withdrawn | Jan 17, 2013 | Fred Hutchinson Cancer Center | not stated | Not stated |
| NCT00916045 | Pilot Study of Unrelated Cord Blood Transplantation | Phase 2 | terminated | Jun 8, 2009 | King's College Hospital NHS Trust | Recruitment issues | Enrollment / accrual |
| NCT02070393 | Breast-Sparing Proton Therapy for Hodgkin's Disease(Breast Sparing) | Early Phase 1 | terminated | Feb 25, 2014 | Indiana University | Closure of Indiana University Health Proton Center in December 2014 | Other (stated, no rule matched) |
| NCT00649584 | A Phase I Dose Escalation Study of SGN-35 Alone and in Combination With Gemcitabine for… | Phase 1 | terminated | Apr 1, 2008 | Seagen Inc. | Sponsor decision not to enroll cohorts of combined SGN-35 and gemcitabine therapy. | Enrollment / accrual |
| NCT00288067 | Fenretinide and Rituximab in Treating Patients With B-Cell Non-Hodgkin Lymphoma | Phase 1 / Phase 2 | terminated | Feb 7, 2006 | National Cancer Institute (NCI) | NCI stopped supplying fenretinide in November of 2012. | Other (stated, no rule matched) |
| NCT00594308 | In-Vivo Activated T-Cell Depletion to Prevent GVHD | N/A | terminated | Jan 15, 2008 | Indiana University | Treatment ineffective | Other (stated, no rule matched) |
| NCT00225173 | Combination Chemotherapy +/- Radiation in High Risk Hodgkin's Disease | Phase 2 | terminated | Sep 23, 2005 | Stanford University | not stated | Not stated |
| NCT00089076 | MDX-010 in Treating Patients With Recurrent or Refractory Lymphoma | Phase 1 / Phase 2 | terminated | Aug 5, 2004 | National Cancer Institute (NCI) | not stated | Not stated |
| NCT00096005 | Tanespimycin and Bortezomib in Treating Patients With Advanced Solid Tumors or Lymphomas | Phase 1 | terminated | Nov 9, 2004 | National Cancer Institute (NCI) | not stated | Not stated |
| NCT01500161 | Pooled Unrelated Donor Umbilical Cord Blood Transplant For Hematologic Malignancy Needing… | Phase 2 | terminated | Dec 28, 2011 | Texas Oncology Cancer Center | Insufficient accruals | Enrollment / accrual |
| NCT00514722 | Pilot Study of Umbilical Cord Blood Transplantation in Adult Patient With Advanced… | N/A | terminated | Aug 10, 2007 | University of California, San Francisco | low accrual | Enrollment / accrual |
| NCT00354185 | PXD101 and 17-N-Allylamino-17-Demethoxygeldanamycin in Treating Patients With Metastatic… | Phase 1 | terminated | Jul 20, 2006 | National Cancer Institute (NCI) | not stated | Not stated |
| NCT00393380 | Study of Parathyroid Hormone Following Sequential Cord Blood Transplantation From an… | Phase 2 | terminated | Oct 27, 2006 | The Emmes Company, LLC | Study stopped because of toxicity concerns. | Safety / toxicity |
| NCT00060112 | Oblimersen and Gemcitabine in Treating Patients With Advanced Solid Tumor or Lymphoma | Phase 1 | terminated | May 7, 2003 | National Cancer Institute (NCI) | Administratively complete. | Other (stated, no rule matched) |
| NCT00086840 | CCI-779 in Treating Patients With Relapsed or Refractory Chronic Lymphocytic Leukemia | Phase 2 | terminated | Jul 12, 2004 | National Cancer Institute (NCI) | Administratively complete. | Other (stated, no rule matched) |
| NCT00101244 | SB-715992 in Treating Patients With Metastatic or Unresectable Solid Tumors or Hodgkin's… | Phase 1 | terminated | Jan 10, 2005 | National Cancer Institute (NCI) | Administratively Complete. | Other (stated, no rule matched) |
| NCT00058773 | Giving Gene Marked EBV Specific T-Cells to Patients Receiving a BMT for Relapsed…(ANGELA) | Phase 1 | terminated | Apr 15, 2003 | Baylor College of Medicine | not stated | Not stated |
| NCT00038818 | CD8 DLI for Patients With Relapse or Residual Disease Following Allogeneic Stem Cell… | N/A | terminated | Jun 7, 2002 | M.D. Anderson Cancer Center | Low accrual. | Enrollment / accrual |
| NCT01558778 | Mechanical Stimulation in Preventing Bone Density Loss in Patients Undergoing Donor Stem… | N/A | withdrawn | Mar 20, 2012 | Roswell Park Cancer Institute | device not available | Other (stated, no rule matched) |
| NCT00383097 | Lmp1 and Lmp2 Specific CTLs Following Cd45 Antibody for Relapsed Ebv-Positive Hodgkin's…(ALDI) | Phase 1 | terminated | Oct 2, 2006 | Baylor College of Medicine | The trial was terminated in 2010 due to lack of enrollment. | Enrollment / accrual |
| NCT01452334 | Safety Study of Anti-Programmed Death-Ligand 1 in Hematologic Malignancy | Phase 1 | withdrawn | Oct 14, 2011 | Bristol-Myers Squibb | not stated | Not stated |
| NCT01116154 | Vorinostat and Lenalidomide in Treating Patients With Relapsed or Refractory Hodgkin… | Phase 1 | terminated | May 4, 2010 | City of Hope Medical Center | Sponsor withdrew support for the study | Other (stated, no rule matched) |
| NCT00275262 | A Study to Evaluate the Ability of Lupron Depot to Enhance Immune Function Following Bone… | Phase 2 | terminated | Jan 11, 2006 | Abbott | not stated | Not stated |
| NCT00209014 | Phase II Trial of Thalidomide in Refractory/Relapsed Diffuse Large B-Cell Lymphoma and… | Phase 2 | terminated | Sep 21, 2005 | Emory University | Celgene unable to continue funds. | Funding |
| NCT00148018 | Study of Bortezomib (Velcade) in Combination With Dexamethasone to Treat Patients With… | Phase 2 | terminated | Sep 7, 2005 | University of Cologne | not stated | Not stated |
Stop reasons are registrant-reported free text and are displayed verbatim (truncated; hover for the full text). Categories come from explicit keyword rules and are never inferred from the study design, sponsor or outcome; a study that stopped for several reasons is filed under the first rule that matched. A TERMINATED status does not imply a negative result.
Data updated 22 days agoSource updated Jun 27, 2017source: clinicaltrials