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Clinical trials · failure tracking
Oncology studies whose overall status is TERMINATED, WITHDRAWN or SUSPENDED on ClinicalTrials.gov, with the stop reason exactly as the registrant posted it. A category is attached only when an explicit keyword rule matches the text; CancerIndex never infers why a study stopped.
28 stopped studies mapped to Breast Ductal Carcinoma In Situ and descendants · 93% state a reason
Over the 28 studies matching the cancer, status and year filters (the category filter does not change this chart). Each study is counted once, in the first matching category; greyed bars are studies whose text matched no rule or was empty.
Computedrules ci-stop-reasons-v1 · keyword matching only
A category is assigned when one of its keywords appears in the posted text (case-insensitive, whole words). Rules are tested in this order and the first match wins; every match is kept in the API (reasonMatches).
| NCT | Title | Phase | Status | First posted | Lead sponsor | Why stopped (as posted) | Category |
|---|---|---|---|---|---|---|---|
| NCT03077841 | Hypofractionated Partial Breast Irradiation in Treating Patients With Early Stage Breast… | Phase 2 / Phase 3 | suspended | Mar 13, 2017 | M.D. Anderson Cancer Center | PI Requested | Other (stated, no rule matched) |
| NCT06671912 | Testing Low Dose Tamoxifen for Invasive Breast Cancer, LoTam Trial(LoTam) | Phase 3 | suspended | Nov 4, 2024 | Alliance for Clinical Trials in Oncology | Amending protocol to increase sample size | Other (stated, no rule matched) |
| NCT06538389 | High Cannabidiol Plant Extract (BRC-001) to Improve Aromatase Inhibitor-Induced… | Phase 2 | suspended | Aug 5, 2024 | City of Hope Medical Center | Accrual goal met | Enrollment / accrual |
| NCT06617455 | Fezolinetant for the Improvement of Vasomotor Symptoms in Breast Cancer Patients Taking…(VEnT) | Phase 2 | terminated | Sep 27, 2024 | University of Michigan Rogel Cancer Center | Lack of Patient Interest | Other (stated, no rule matched) |
| NCT02856503 | Effect of High Dose Vitamin D on Cancer Biomarkers and Breast Cancer Tumors | Phase 1 / Phase 2 | withdrawn | Aug 5, 2016 | Eli Avisar, MD | Lack of Funding | Funding |
| NCT07178665 | Pilot Trial of Preop Partial Radiation in Breast Cancer Patients | Phase 1 | suspended | Sep 17, 2025 | Rutgers, The State University of New Jersey | 10th patient enrolled; interim analysis to be completed by HROC after 3-month follow-up completed… | Efficacy / futility |
| NCT03979508 | Abemaciclib in Treating Patients With Surgically Resectable, Chemotherapy Resistant,… | Phase 2 | terminated | Jun 7, 2019 | Mayo Clinic | The primary biomarker (CD8/FOXP3) was rarely observed to be \< 1.6 in residual tumors examined in… | Other (stated, no rule matched) |
| NCT03535506 | Preoperative Palbociclib in Patients With DCIS of the Breast That Are Candidates for…(WI223281) | Phase 2 | terminated | May 24, 2018 | Georgetown University | lack of accrual | Enrollment / accrual |
| NCT02876640 | Retinoid 9cUAB30 in Producing a Biologic Effect in Patients With Early Stage Breast Cancer | Phase 1 | terminated | Aug 24, 2016 | National Cancer Institute (NCI) | Inadequate Accrual Rate | Enrollment / accrual |
| NCT02127073 | Pilot Study of Oxytocin and microRNA Identification in NAF, Serum, and Tissue in Women… | Phase 2 | terminated | Apr 30, 2014 | Montefiore Medical Center | Could not identify collaborator and secure additional funding after transferring the record to… | Funding |
| NCT05436808 | Partial Chest Wall Radiation Therapy After Surgery for Lymph Node Negative Breast Cancer | Early Phase 1 | withdrawn | Jun 29, 2022 | Stony Brook University | No eligible participants identified | Other (stated, no rule matched) |
| NCT05032079 | Subzero and Scorpion Trial | N/A | withdrawn | Sep 2, 2021 | Larkin Community Hospital | Study Period Ended / Not Completed | Other (stated, no rule matched) |
| NCT04349111 | An Efficacy Study of the Xoft® Axxent® eBx® IORT System® "Lite" | N/A | withdrawn | Apr 16, 2020 | Xoft, Inc. | Lack of site participation | Other (stated, no rule matched) |
| NCT02137252 | Naltrexone RCT for Treatment-Emergent Fatigue in Patients Receiving Radiation Therapy for… | Phase 2 | terminated | May 13, 2014 | Dana-Farber Cancer Institute | no enough patients | Other (stated, no rule matched) |
| NCT03437915 | BrUOG 351: PRE-OPERATIVE APBI USING NIBB(351) | N/A | withdrawn | Feb 19, 2018 | Jaroslaw Hepel | Secondary to medicare coverage determination | Other (stated, no rule matched) |
| NCT01060345 | A Pilot Study of Chemo-prevention of Green Tea in Women With Ductal Carcinoma in Situ | Phase 2 | terminated | Feb 2, 2010 | University of Chicago | Drug no longer available | Other (stated, no rule matched) |
| NCT01138553 | Preoperative Testing of the Anti-Progesterone Mifepristone in Early Stage Breast Cancer | Early Phase 1 | terminated | Jun 7, 2010 | University of California, San Diego | Inadequate subject accrual | Enrollment / accrual |
| NCT02817607 | Study to Assess Breast Sensation Before and After Breast Cancer Treatment | N/A | withdrawn | Jun 29, 2016 | Duke University | not stated | Not stated |
| NCT02168179 | KeraStat Skin Therapy in Treating Radiation Dermatitis in Patients With Newly Diagnosed… | N/A | withdrawn | Jun 20, 2014 | Wake Forest University Health Sciences | No longer pursuing study at our site. | Other (stated, no rule matched) |
| NCT02023008 | Interactive Gentle Yoga in Improving Quality of Life in Patients With Stage I-III Breast… | N/A | terminated | Dec 30, 2013 | Wake Forest University Health Sciences | Study is not feasible | Other (stated, no rule matched) |
| NCT02365714 | CyberKnife Stereotactic Accelerated Partial Breast Irradiation (SAPBI)(CK-SAPBI) | Phase 1 / Phase 2 | terminated | Feb 19, 2015 | Georgetown University | Slow accrual | Enrollment / accrual |
| NCT01372618 | Breast Cancer Chemoprevention by SOM230, an IGF-I Action Inhibitor | Phase 1 / Phase 2 | terminated | Jun 14, 2011 | NYU Langone Health | PI has passed away. Requested by department to terminate study. | Other (stated, no rule matched) |
| NCT01754519 | Radiation Therapy in Treating Post-Menopausal Women With Early Stage Breast Cancer… | Phase 2 | terminated | Dec 21, 2012 | Roswell Park Cancer Institute | IDE not submitted | Other (stated, no rule matched) |
| NCT01729832 | Stereotactic Image-Guided Navigation During Breast Reconstruction in Patients With Breast… | N/A | withdrawn | Nov 20, 2012 | Ohio State University Comprehensive Cancer Center | not stated | Not stated |
| NCT01391039 | Diagnostic Study of Early Breast Cancer Using Ultrasound | N/A | terminated | Jul 11, 2011 | Sunnybrook Health Sciences Centre | Low recruitment | Enrollment / accrual |
| NCT00857714 | Lapatinib for Treatment of Ductal Carcinoma In Situ (DCIS) of the Breast | N/A | terminated | Mar 9, 2009 | Indiana University | Terminated due to low accrual | Enrollment / accrual |
| NCT01791998 | Magnetic Resonance Thermal Image Guided Laser Interstitial Thermal Therapy in Treating… | N/A | withdrawn | Feb 15, 2013 | University of Chicago | Funding was time sensitive and expired. No subjects enrolled. | Enrollment / accrual |
| NCT01100489 | Breast-Conserving Surgery Followed by Radiation Therapy With MRI-Detected Stage I or… | Phase 2 | withdrawn | Apr 9, 2010 | Case Comprehensive Cancer Center | No accrual | Enrollment / accrual |
Stop reasons are registrant-reported free text and are displayed verbatim (truncated; hover for the full text). Categories come from explicit keyword rules and are never inferred from the study design, sponsor or outcome; a study that stopped for several reasons is filed under the first rule that matched. A TERMINATED status does not imply a negative result.
Data updated 16 days agoSource updated Sep 14, 2026source: clinicaltrials