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Genetic correlates of malignancy in TFE3-rearranged PEComa: a series of 14 cases.

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Histopathology2025PMID 40462401PMC12360456stubpubmedProvenance
Source
PubMed
Retrieved
Sep 8, 2026
Layer
normalized (units and labels harmonized; values unchanged)
Run
ING-CIVIC-20260908-000001
Published

Abstract

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Linked entities

Linked entities (3)

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Validated 3

Curated evidence

Evidence citing this paper (1)

civicProvenance
Source
CIViC — Clinical Interpretation of Variants in Cancer
Dataset
CIViC evidence items
Version
civic-2026-09-08
Retrieved
Sep 8, 2026
Layer
normalized (units and labels harmonized; values unchanged)
Evidence
expert curation
License
CC0 1.0
PMID
40462401
Run
ING-CIVIC-20260908-000001
Open at source
CuratedShowing 1–1 of 1 evidence items · levels, directions and significance as curated at the source; each row links to its CIViC record.
TherapyCancerTypeLevelDirection · significanceRating (1–5)StatusEvidenceSource
TFE3 Fusion1
(diagnostic)PEComaALIASDiagnosticBSupports Positive3accepted
EID12691

In this 2025 study, the authors included 14 confirmed TFE3-rearranged perivascular epithelioid cell tumors (PEComas), previously classified as benign (9 tumors) or malignant (5 tumors), and compared t… (full text at CIViC)

PMID 40462401 · Papke et al., 2025 · Open in CIViC

civic