Publication
Angiomatoid fibrous histiocytoma with EWSR1-CREB1 gene fusion occurs in lungs and ribs with systemic multiple metastases: a case report and review of the literature.
Authors not recorded
- Source
- PubMed
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CIVIC-20260908-000001
Abstract
Abstract (excerpt)
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Linked entities
Linked entities (3)
How each link was made (MeSH, dictionary, registry reference, curation…) and whether it has been validated. Candidate links are not counted in entity statistics.
Validated 3
- cancerAngiomatoid Fibrous Histiocytomacivic_curation1.00
- geneCREB1civic_curation1.00
- variantCREB1 Fusioncivic_curation1.00
Curated evidence
Evidence citing this paper (2)
- Source
- CIViC — Clinical Interpretation of Variants in Cancer
- Dataset
- CIViC evidence items
- Version
- civic-2026-09-08
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- expert curation
- License
- CC0 1.0
- PMID
- 39845329
- Run
- ING-CIVIC-20260908-000001
| Therapy | Cancer | Type | Level | Direction · significance | Rating (1–5) | Status | Evidence | Source |
|---|---|---|---|---|---|---|---|---|
| CREB1 Fusion2 | ||||||||
| (diagnostic) | Angiomatoid Fibrous Histiocytoma | Diagnostic | C | Supports Positive | 3 | accepted | EID12853In this study, the authors report a 34‑year-old patient with angiomatoid fibrous histiocytoma (AFH) who initially presented with a pulmonary nodule and a 4th‑rib lesion and subsequently developed meta… (full text at CIViC) PMID 39845329 · Feng et al., 2024 · Open in CIViC | civic |
| (prognostic) | Angiomatoid Fibrous Histiocytoma | Prognostic | C | Supports Poor Outcome | 1 | rejected | EID12854The EWSR1::CREB1 fusion associated with t(2;22)(q33;q12) represents a defining diagnostic alteration in angiomatoid fibrous histiocytoma (AFH); in this case, a 34‑year‑old patient initially presented … (full text at CIViC) PMID 39845329 · Feng et al., 2024 · Open in CIViC | civic |