ALK Fusion

CI-VAR-00001349Explore in graph →CIViC 4308

Curated evidence

Evidence by cancer (1 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

civicCuratedShowing 1–1 of 1 evidence items across 1 cancer context on this page · levels, directions and significance as curated at the source; each row links to its CIViC record.

Molecular profile	Therapy	Type	Level	Direction · significance	Rating (1–5)	Status	Evidence	Source
Sarcoma1
ERC1::ALK Fusion	Crizotinib	Predictive	C	Supports Sensitivity Response	4	submitted	EID11032 Case study of a 2-year-old male with a slowly enlarging mass and gradual loss of function in right hand. First considered to be a vascular malformation. Tumor involved soft tissue spaces around a… (full text at CIViC) PMID 34464935 · Chen et al., 2021 · Open in CIViC	civic

ClinVar

Clinical significance (0)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

Data not yet available

No ClinVar interpretation attached to this variant.