Publication
Recurrent genetic fusions redefine MLL germ line acute lymphoblastic leukemia in infants.
Authors not recorded
Blood2021PMID 33512459stubpubmedProvenance
- Source
- PubMed
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CIVIC-20260908-000001
Abstract
Abstract (excerpt)
Only the opening of the abstract is shown; abstract text may carry publisher copyright.
Data not yet available
No abstract stored. Read on PubMed
Linked entities
Linked entities (2)
How each link was made (MeSH, dictionary, registry reference, curation…) and whether it has been validated. Candidate links are not counted in entity statistics.
Validated 2
- geneNUTM1civic_curation1.00
- variantNUTM1 Fusioncivic_curation1.00
Curated evidence
Evidence citing this paper (1)
civicProvenance
- Source
- CIViC — Clinical Interpretation of Variants in Cancer
- Dataset
- CIViC evidence items
- Version
- civic-2026-09-08
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- expert curation
- License
- CC0 1.0
- PMID
- 33512459
- Run
- ING-CIVIC-20260908-000001
| Therapy | Cancer | Type | Level | Direction · significance | Rating (1–5) | Status | Evidence | Source |
|---|---|---|---|---|---|---|---|---|
| NUTM1 Fusion1 | ||||||||
| (diagnostic) | B-lymphoblastic Leukemia With NUTM1 RearrangementUNRESOLVED | Diagnostic | B | Supports Positive | 4 | accepted | EID12239This 2021 study highlights the diagnostic significance of NUTM1 rearrangements in infants with B lymphoblastic leukemia (B-ALL) negative for KMT2A rearrangements. Among the 30 analyzed cases of KMT2A-… (full text at CIViC) PMID 33512459 · Fazio et al., 2021 · Open in CIViC | civic |