Publication
Successful treatment of lipofibromatosis-like neural tumor of the lumbar spine with an NTRK-fusion inhibitor.
Authors not recorded
- Source
- PubMed
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CIVIC-20260908-000001
Abstract
Abstract (excerpt)
Only the opening of the abstract is shown; abstract text may carry publisher copyright.
Data not yet available
Linked entities
Linked entities (4)
How each link was made (MeSH, dictionary, registry reference, curation…) and whether it has been validated. Candidate links are not counted in entity statistics.
Validated 4
- cancerNTRK-Rearranged Spindle Cell Neoplasmcivic_curation1.00
- drugEntrectinibcivic_curation1.00
- geneNTRK1civic_curation1.00
- variantNTRK1 Fusioncivic_curation1.00
Curated evidence
Evidence citing this paper (2)
- Source
- CIViC — Clinical Interpretation of Variants in Cancer
- Dataset
- CIViC evidence items
- Version
- civic-2026-09-08
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- expert curation
- License
- CC0 1.0
- PMID
- 32782782
- Run
- ING-CIVIC-20260908-000001
| Therapy | Cancer | Type | Level | Direction · significance | Rating (1–5) | Status | Evidence | Source |
|---|---|---|---|---|---|---|---|---|
| NTRK1 Fusion2 | ||||||||
| (diagnostic) | NTRK-Rearranged Spindle Cell NeoplasmALIAS | Diagnostic | C | Supports Positive | 3 | accepted | EID11577A 21-year-old man demonstrated intermittent abdominal pain, and a CT scan revealed an abnormal paraspinal lesion. Biopsy revealed a spindle cell mesenchymal tumor with monotonous, bland spindle cells … (full text at CIViC) PMID 32782782 · Dupuis et al., 2020 · Open in CIViC | civic |
| Entrectinib | NTRK-Rearranged Spindle Cell NeoplasmALIAS | Predictive | C | Supports Sensitivity Response | 3 | accepted | EID11578A 21-year-old man demonstrated intermittent abdominal pain, and a CT scan revealed an abnormal paraspinal lesion. IHC was positive for CD34, S-100, and pan-TRK and negative for Sox10. Anchored multip… (full text at CIViC) PMID 32782782 · Dupuis et al., 2020 · Open in CIViC | civic |