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NUTM1 is a recurrent fusion gene partner in B-cell precursor acute lymphoblastic leukemia associated with increased expression of genes on chromosome band 10p12.31-12.2.

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Haematologica2019PMID 30872366PMC6886436stubpubmedProvenance
Source
PubMed
Retrieved
Sep 8, 2026
Layer
normalized (units and labels harmonized; values unchanged)
Run
ING-CIVIC-20260908-000001
Published

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Linked entities (2)

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Curated evidence

Evidence citing this paper (1)

civicProvenance
Source
CIViC — Clinical Interpretation of Variants in Cancer
Dataset
CIViC evidence items
Version
civic-2026-09-08
Retrieved
Sep 8, 2026
Layer
normalized (units and labels harmonized; values unchanged)
Evidence
expert curation
License
CC0 1.0
PMID
30872366
Run
ING-CIVIC-20260908-000001
Open at source
CuratedShowing 1–1 of 1 evidence items · levels, directions and significance as curated at the source; each row links to its CIViC record.
TherapyCancerTypeLevelDirection · significanceRating (1–5)StatusEvidenceSource
NUTM1 Fusion1
(diagnostic)B-lymphoblastic Leukemia With NUTM1 RearrangementUNRESOLVEDDiagnosticBSupports Positive4accepted
EID12237

In this 2019 study, the authors investigated the association between NUTM1 rearrangements and B-lymphoblastic leukemia (B-ALL) in a cohort of pediatric and infant patients, up to 14 years of age. NUTM… (full text at CIViC)

PMID 30872366 · Hormann et al., 2019 · Open in CIViC

civic