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BCOR-CCNB3 Undifferentiated Sarcoma-Does Immunohistochemistry Help in the Identification?

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Pediatr Dev Pathol2017PMID 28420319stubpubmedProvenance
Source
PubMed
Retrieved
Sep 8, 2026
Layer
normalized (units and labels harmonized; values unchanged)
Run
ING-CIVIC-20260908-000001
Published

Abstract

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Linked entities

Linked entities (3)

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Validated 3

Curated evidence

Evidence citing this paper (1)

civicProvenance
Source
CIViC — Clinical Interpretation of Variants in Cancer
Dataset
CIViC evidence items
Version
civic-2026-09-08
Retrieved
Sep 8, 2026
Layer
normalized (units and labels harmonized; values unchanged)
Evidence
expert curation
License
CC0 1.0
PMID
28420319
Run
ING-CIVIC-20260908-000001
Open at source
CuratedShowing 1–1 of 1 evidence items · levels, directions and significance as curated at the source; each row links to its CIViC record.
TherapyCancerTypeLevelDirection · significanceRating (1–5)StatusEvidenceSource
CCNB3 Fusion1
(diagnostic)Sarcoma with BCOR Genetic AlterationsDiagnosticBSupports Positive3accepted
EID12568

In this 2017 study reviewing 753 sarcoma cases, 11 tumors with the BCOR::CCNB3 fusion were identified using immunohistochemistry and RT-PCR. These tumors were found exclusively in males, with a mean a… (full text at CIViC)

PMID 28420319 · Ludwig et al., 2017 · Open in CIViC

civic