Skip to content
CancerIndex

Publication

CTCF genetic alterations in endometrial carcinoma are pro-tumorigenic.

Authors not recorded

Oncogene2017PMID 28319062PMC5519450stubpubmedProvenance
Source
PubMed
Retrieved
Sep 8, 2026
Layer
normalized (units and labels harmonized; values unchanged)
Run
ING-CIVIC-20260908-000001
Published

Abstract

Abstract (excerpt)

Only the opening of the abstract is shown; abstract text may carry publisher copyright.

Data not yet available

No abstract stored. Read on PubMed

Linked entities

Linked entities (2)

How each link was made (MeSH, dictionary, registry reference, curation…) and whether it has been validated. Candidate links are not counted in entity statistics.

Validated 2

Curated evidence

Evidence citing this paper (3)

civicProvenance
Source
CIViC — Clinical Interpretation of Variants in Cancer
Dataset
CIViC evidence items
Version
civic-2026-09-08
Retrieved
Sep 8, 2026
Layer
normalized (units and labels harmonized; values unchanged)
Evidence
expert curation
License
CC0 1.0
PMID
28319062
Run
ING-CIVIC-20260908-000001
Open at source CuratedShowing 1–3 of 3 evidence items · levels, directions and significance as curated at the source; each row links to its CIViC record.
TherapyCancerTypeLevelDirection · significanceRating (1–5)StatusEvidenceSource
CTCF K365T1
(functional)—UNRESOLVEDFunctionalDSupports Gain Of Function3accepted
EID10179

Three recurrent CTCF mutations found in endometrial carcinoma were expressed in Ishikawa cells and compared to expression of wild-type CTCF. The K365T mutation did not demonstrate altered localization… (full text at CIViC)

PMID 28319062 · Marshall et al., 2017 · Open in CIViC

civic
CTCF P378L1
(functional)—UNRESOLVEDFunctionalDSupports Loss Of Function3submitted
EID9173

Three recurrent CTCF mutations found in endometrial carcinoma were expressed in Ishikawa cells and compared to expression of wild-type CTCF. CTCF P378L showed similar nuclear localization and protein … (full text at CIViC)

PMID 28319062 · Marshall et al., 2017 · Open in CIViC

civic
CTCF R377H1
(functional)—UNRESOLVEDFunctionalDSupports Loss Of Function3submitted
EID9327

Three recurrent CTCF mutations found in endometrial carcinoma were expressed in Ishikawa cells and compared to expression of wild-type CTCF. CTCF R377H showed similar nuclear localization and protein … (full text at CIViC)

PMID 28319062 · Marshall et al., 2017 · Open in CIViC

civic