Publication
Nuclear heat shock protein 110 expression is associated with poor prognosis and chemotherapy resistance in gastric cancer.
Authors not recorded
- Source
- PubMed
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CIVIC-20260908-000001
Abstract
Abstract (excerpt)
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Linked entities
Linked entities (5)
How each link was made (MeSH, dictionary, registry reference, curation…) and whether it has been validated. Candidate links are not counted in entity statistics.
Validated 5
- cancerGastric Adenocarcinomacivic_curation1.00
- drugCisplatincivic_curation1.00
- drugFluorouracilcivic_curation1.00
- geneHSPH1civic_curation1.00
- variantHSPH1 NUCLEAR EXPRESSIONcivic_curation1.00
Curated evidence
Evidence citing this paper (2)
- Source
- CIViC — Clinical Interpretation of Variants in Cancer
- Dataset
- CIViC evidence items
- Version
- civic-2026-09-08
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- expert curation
- License
- CC0 1.0
- PMID
- 26943774
- Run
- ING-CIVIC-20260908-000001
| Therapy | Cancer | Type | Level | Direction · significance | Rating (1–5) | Status | Evidence | Source |
|---|---|---|---|---|---|---|---|---|
| HSPH1 NUCLEAR EXPRESSION2 | ||||||||
| (prognostic) | Gastric Adenocarcinoma | Prognostic | B | Supports Poor Outcome | 2 | accepted | EID1162HSP110 (HSPH1) expression was immunohistochemically assessed using a tissue microarray in 210 gastric cancer patients. The overall survival rate was significantly lower in patients with high nuclear e… (full text at CIViC) PMID 26943774 · Kimura et al., 2016 · Open in CIViC | civic |
| Cisplatin + FluorouracilSubstitutes | Gastric Adenocarcinoma | Predictive | D | Supports Sensitivity Response | 1 | accepted | EID116349 patients gastric cancer patients treated with adjuvant chemotherapy were immunohistochemically assessed for nuclear HSPH1 (HSP110) expression. Overall survival rate in the high expression group (2+… (full text at CIViC) PMID 26943774 · Kimura et al., 2016 · Open in CIViC | civic |