Publication
TERT mutation in glioma: Frequency, prognosis and risk.
Authors not recorded
- Source
- PubMed
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CIVIC-20260908-000001
Abstract
Abstract (excerpt)
Only the opening of the abstract is shown; abstract text may carry publisher copyright.
Data not yet available
Linked entities
Linked entities (3)
How each link was made (MeSH, dictionary, registry reference, curation…) and whether it has been validated. Candidate links are not counted in entity statistics.
Validated 3
- geneTERTcivic_curation1.00
- variantTERT Promoter Mutationcivic_curation1.00
- variantTERT RS2736100civic_curation1.00
Curated evidence
Evidence citing this paper (2)
- Source
- CIViC — Clinical Interpretation of Variants in Cancer
- Dataset
- CIViC evidence items
- Version
- civic-2026-09-08
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- expert curation
- License
- CC0 1.0
- PMID
- 26765760
- Run
- ING-CIVIC-20260908-000001
| Therapy | Cancer | Type | Level | Direction · significance | Rating (1–5) | Status | Evidence | Source |
|---|---|---|---|---|---|---|---|---|
| TERT Promoter Mutation1 | ||||||||
| (diagnostic) | Brain GliomaUNRESOLVED | Diagnostic | B | Supports Positive | 3 | accepted | EID976In this meta-analysis of 16 Trials, TERT mutations were more common in glioblastomas (69%), oligodendrogliomas (72%) in comparison to astrocytomas (24%) and oligoastrocytomas (38%). PMID 26765760 · Yuan et al., 2016 · Open in CIViC | civic |
| TERT RS27361001 | ||||||||
| (predisposing) | Brain GliomaUNRESOLVED | Predisposing | B | Supports Predisposition | 2 | accepted | EID980Meta-analysis of 10 studies (9,411 patients, 13,708 controls) showed that TERT polymorphisms (rs2736100) were associated with an increased glioma risk (RR=1.28, 95% CI 1.23-1.33). PMID 26765760 · Yuan et al., 2016 · Open in CIViC | civic |