Publication
CD44 variant 6 is correlated with peritoneal dissemination and poor prognosis in patients with advanced epithelial ovarian cancer.
Authors not recorded
- Source
- PubMed
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CIVIC-20260908-000001
Abstract
Abstract (excerpt)
Only the opening of the abstract is shown; abstract text may carry publisher copyright.
Data not yet available
Linked entities
Linked entities (3)
How each link was made (MeSH, dictionary, registry reference, curation…) and whether it has been validated. Candidate links are not counted in entity statistics.
Validated 3
- cancerMalignant Ovarian Neoplasmcivic_curation1.00
- geneCD44civic_curation1.00
- variantCD44 CD44v6civic_curation1.00
Curated evidence
Evidence citing this paper (2)
- Source
- CIViC — Clinical Interpretation of Variants in Cancer
- Dataset
- CIViC evidence items
- Version
- civic-2026-09-08
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- expert curation
- License
- CC0 1.0
- PMID
- 26250934
- Run
- ING-CIVIC-20260908-000001
| Therapy | Cancer | Type | Level | Direction · significance | Rating (1–5) | Status | Evidence | Source |
|---|---|---|---|---|---|---|---|---|
| CD44 CD44v62 | ||||||||
| (prognostic) | Malignant Ovarian Neoplasm | Prognostic | B | Supports Poor Outcome | 4 | accepted | EID9427In a clinical study including 59 stage III-IV ovarian cancer patients with peritoneal disseminated tumors, Kaplan-Meier analysis showed a significant association between CD44v6 high expression and wor… (full text at CIViC) PMID 26250934 · Tjhay et al., 2015 · Open in CIViC | civic |
| Cisplatin | Malignant Ovarian Neoplasm | Predictive | D | Supports Resistance | 3 | submitted | EID9429In an in vitro chemosensitivtiy assay, FACS-sorted CD44v6-positive cells show a significantly higher viability compared to CD44v6-negative cells when treated with 10nM of paclitaxel or 9 uM of cisplat… (full text at CIViC) PMID 26250934 · Tjhay et al., 2015 · Open in CIViC | civic |