Publication
TCGA, Nature 2014
Authors not recorded
- Source
- PubMed
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CBIOPORTAL-20260908-000001
Abstract
Abstract (excerpt)
Only the opening of the abstract is shown; abstract text may carry publisher copyright.
Data not yet available
Linked entities
Linked entities (1)
How each link was made (MeSH, dictionary, registry reference, curation…) and whether it has been validated. Candidate links are not counted in entity statistics.
Validated 1
- cancerLung Adenocarcinomacbioportal_study1.00
Curated evidence
Evidence citing this paper (2)
- Source
- CIViC — Clinical Interpretation of Variants in Cancer
- Dataset
- CIViC evidence items
- Version
- civic-2026-09-08
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- expert curation
- License
- CC0 1.0
- PMID
- 25079552
- Run
- ING-CIVIC-20260908-000001
| Therapy | Cancer | Type | Level | Direction · significance | Rating (1–5) | Status | Evidence | Source |
|---|---|---|---|---|---|---|---|---|
| ERBB2 Amplification + MET AmplificationERBB2MET1 | ||||||||
| (diagnostic) | Lung Adenocarcinoma | Diagnostic | B | Supports Positive | 5 | submitted | EID11372This study contained 230 patients presenting with untreated lung adenocarcinoma. Tumor and matched normal material were analyzed via whole-exome sequencing. It was shown that ~62% of samples contained… (full text at CIViC) PMID 25079552 · 2014, Nature · Open in CIViC | civic |
| NF1 Mutation + RIT1 MutationRIT1NF11 | ||||||||
| (diagnostic) | Lung Adenocarcinoma | Diagnostic | B | Supports Positive | 5 | submitted | EID11373This study contained 230 patients with untreated lung adenocarcinoma. Whole-exome sequencing of tumor cells yielded that RTK/RAS/RAF based mutations to be 62%. However, analysis shows that NF1 mutatio… (full text at CIViC) PMID 25079552 · 2014, Nature · Open in CIViC | civic |