Publication
Characterization of novel genomic alterations and therapeutic approaches using acute megakaryoblastic leukemia xenograft models.
Authors not recorded
J Exp Med2012PMID 23045605PMC3478932stubpubmedProvenance
- Source
- PubMed
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CIVIC-20260908-000001
Abstract
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Linked entities
Linked entities (2)
How each link was made (MeSH, dictionary, registry reference, curation…) and whether it has been validated. Candidate links are not counted in entity statistics.
Validated 2
- geneGLIS2civic_curation1.00
- variantGLIS2 Fusioncivic_curation1.00
Curated evidence
Evidence citing this paper (1)
civicProvenance
- Source
- CIViC — Clinical Interpretation of Variants in Cancer
- Dataset
- CIViC evidence items
- Version
- civic-2026-09-08
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- expert curation
- License
- CC0 1.0
- PMID
- 23045605
- Run
- ING-CIVIC-20260908-000001
| Therapy | Cancer | Type | Level | Direction · significance | Rating (1–5) | Status | Evidence | Source |
|---|---|---|---|---|---|---|---|---|
| GLIS2 Fusion1 | ||||||||
| (diagnostic) | Acute Myeloid Leukemia With CBFA2T3::GLIS2 FusionUNRESOLVED | Diagnostic | B | Supports Positive | 4 | accepted | EID11885In this 2012 study the authors performed high-throughput sequencing of RNA (RNA-seq) of leukemic cells obtained after engraftment in immunodeficient mice from 5 patients with Acute megakaryoblastic le… (full text at CIViC) PMID 23045605 · Thiollier et al., 2012 · Open in CIViC | civic |