Publication
IDH2 mutations are frequent in angioimmunoblastic T-cell lymphoma.
Authors not recorded
Blood2012PMID 22215888PMC3293643stubpubmedProvenance
- Source
- PubMed
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CIVIC-20260908-000001
Abstract
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Linked entities
Linked entities (3)
How each link was made (MeSH, dictionary, registry reference, curation…) and whether it has been validated. Candidate links are not counted in entity statistics.
Validated 3
- cancerPeripheral T-Cell Lymphoma, Not Otherwise Specifiedcivic_curation1.00
- geneIDH2civic_curation1.00
- variantIDH2 R172civic_curation1.00
Curated evidence
Evidence citing this paper (1)
civicProvenance
- Source
- CIViC — Clinical Interpretation of Variants in Cancer
- Dataset
- CIViC evidence items
- Version
- civic-2026-09-08
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- expert curation
- License
- CC0 1.0
- PMID
- 22215888
- Run
- ING-CIVIC-20260908-000001
| Therapy | Cancer | Type | Level | Direction · significance | Rating (1–5) | Status | Evidence | Source |
|---|---|---|---|---|---|---|---|---|
| IDH2 R1721 | ||||||||
| (diagnostic) | Peripheral T-Cell Lymphoma, Not Otherwise Specified | Diagnostic | B | Supports Positive | 4 | accepted | EID628IDH2 R172 mutations were frequently observed in patients with the angioimmunoblastic T-cell lymphoma subtype of peripheral T-cell lymphomas but not observed in other subtypes. PMID 22215888 · Cairns et al., 2012 · Open in CIViC | civic |