Publication
Significance of RRM1 and ERCC1 expression in resectable pancreatic adenocarcinoma.
Authors not recorded
Oncogene2009PMID 19543324PMC3913371stubpubmedProvenance
- Source
- PubMed
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CIVIC-20260908-000001
Abstract
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Linked entities
Linked entities (4)
How each link was made (MeSH, dictionary, registry reference, curation…) and whether it has been validated. Candidate links are not counted in entity statistics.
Validated 4
- cancerMalignant Pancreatic Neoplasmcivic_curation1.00
- drugGemcitabinecivic_curation1.00
- geneRRM1civic_curation1.00
- variantRRM1 Underexpressioncivic_curation1.00
Curated evidence
Evidence citing this paper (1)
civicProvenance
- Source
- CIViC — Clinical Interpretation of Variants in Cancer
- Dataset
- CIViC evidence items
- Version
- civic-2026-09-08
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- expert curation
- License
- CC0 1.0
- PMID
- 19543324
- Run
- ING-CIVIC-20260908-000001
| Therapy | Cancer | Type | Level | Direction · significance | Rating (1–5) | Status | Evidence | Source |
|---|---|---|---|---|---|---|---|---|
| RRM1 Underexpression1 | ||||||||
| Gemcitabine | Malignant Pancreatic Neoplasm | Predictive | B | Supports Sensitivity Response | 3 | accepted | EID5506There were 68 patients enrolled in this study, 28 of which were treated with gemcitabine. Of those 28, 14 patients had a low RRM1 expression and 14 had a high RRM1 expression. Only the patients with … (full text at CIViC) PMID 19543324 · Akita et al., 2009 · Open in CIViC | civic |