Publication
High incidence of t(7;12)(q36;p13) in infant AML but not in infant ALL, with a dismal outcome and ectopic expression of HLXB9.
Authors not recorded
Genes Chromosomes Cancer2006PMID 16646086stubpubmedProvenance
- Source
- PubMed
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CIVIC-20260908-000001
Abstract
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Linked entities
Linked entities (2)
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Validated 2
- geneETV6civic_curation1.00
- variantETV6 Fusioncivic_curation1.00
Curated evidence
Evidence citing this paper (1)
civicProvenance
- Source
- CIViC — Clinical Interpretation of Variants in Cancer
- Dataset
- CIViC evidence items
- Version
- civic-2026-09-08
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- expert curation
- License
- CC0 1.0
- PMID
- 16646086
- Run
- ING-CIVIC-20260908-000001
| Therapy | Cancer | Type | Level | Direction · significance | Rating (1–5) | Status | Evidence | Source |
|---|---|---|---|---|---|---|---|---|
| ETV6 Fusion1 | ||||||||
| (diagnostic) | Acute Myeloid Leukemia With MNX1::ETV6 FusionUNRESOLVED | Diagnostic | B | Supports Positive | 3 | accepted | EID12092In this 2006 study, the authors examined cytogenetics for the presence of a 7q31-36 and 12p11-13 chromosomal abnormality in 320 infants and pediatric ALL and AML patients younger than 36 months of age… (full text at CIViC) PMID 16646086 · von Bergh et al., 2006 · Open in CIViC | civic |