ETV6 Fusion

CI-VAR-00001423Explore in graph →CIViC 4999

Curated evidence

Evidence by cancer (3 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

civicCuratedShowing 1–3 of 3 evidence items across 1 cancer context on this page · levels, directions and significance as curated at the source; each row links to its CIViC record.

Molecular profile	Therapy	Type	Level	Direction · significance	Rating (1–5)	Status	Evidence	Source
Acute Myeloid Leukemia With MNX1::ETV6 Fusion3unmapped disease
MNX1::ETV6 Fusion	(diagnostic)	Diagnostic	B	Supports Positive	3	accepted	EID12091 In this 2001 study, the authors identified AML patients with 7q and 12p (ETV6) cytogenetic abnormalities from a cohort of 130 patients aged 0 to 17 years. Of the 125 cases with suitable karyotypes, 5 … (full text at CIViC) PMID 11417477 · Slater et al., 2001 · Open in CIViC	civic
MNX1::ETV6 Fusion	(diagnostic)	Diagnostic	B	Supports Positive	3	accepted	EID12092 In this 2006 study, the authors examined cytogenetics for the presence of a 7q31-36 and 12p11-13 chromosomal abnormality in 320 infants and pediatric ALL and AML patients younger than 36 months of age… (full text at CIViC) PMID 16646086 · von Bergh et al., 2006 · Open in CIViC

ClinVar

Clinical significance (0)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

Data not yet available

No ClinVar interpretation attached to this variant.