Variant · Fusion
ETV6 Fusion
CI-VAR-00001423Explore in graph →CIViC 4999
Curated evidence
Evidence by cancer (3 items)
Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.
- Source
- CIViC — Clinical Interpretation of Variants in Cancer
- Dataset
- CIViC evidence items
- Version
- civic-2026-09-08
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- expert curation
- License
- CC0 1.0
- PMID
- 11417477
- Run
- ING-CIVIC-20260908-000001
| Molecular profile | Therapy | Type | Level | Direction · significance | Rating (1–5) | Status | Evidence | Source |
|---|---|---|---|---|---|---|---|---|
| Acute Myeloid Leukemia With MNX1::ETV6 Fusion3unmapped disease | ||||||||
| MNX1::ETV6 Fusion | (diagnostic) | Diagnostic | B | Supports Positive | 3 | accepted | EID12091In this 2001 study, the authors identified AML patients with 7q and 12p (ETV6) cytogenetic abnormalities from a cohort of 130 patients aged 0 to 17 years. Of the 125 cases with suitable karyotypes, 5 … (full text at CIViC) PMID 11417477 · Slater et al., 2001 · Open in CIViC | civic |
| MNX1::ETV6 Fusion | (diagnostic) | Diagnostic | B | Supports Positive | 3 | accepted | EID12092In this 2006 study, the authors examined cytogenetics for the presence of a 7q31-36 and 12p11-13 chromosomal abnormality in 320 infants and pediatric ALL and AML patients younger than 36 months of age… (full text at CIViC) PMID 16646086 · von Bergh et al., 2006 · Open in CIViC | |
ClinVar
Clinical significance (0)
ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.
Data not yet available