Publication
Constitutive activating mutation of the FGFR3b in oral squamous cell carcinomas.
Authors not recorded
Int J Cancer2005PMID 15880580stubpubmedProvenance
- Source
- PubMed
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CIVIC-20260908-000001
Abstract
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Linked entities
Linked entities (2)
How each link was made (MeSH, dictionary, registry reference, curation…) and whether it has been validated. Candidate links are not counted in entity statistics.
Validated 2
- geneFGFR3civic_curation1.00
- variantFGFR3 G697Ccivic_curation1.00
Curated evidence
Evidence citing this paper (1)
civicProvenance
- Source
- CIViC — Clinical Interpretation of Variants in Cancer
- Dataset
- CIViC evidence items
- Version
- civic-2026-09-08
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- expert curation
- License
- CC0 1.0
- PMID
- 15880580
- Run
- ING-CIVIC-20260908-000001
| Therapy | Cancer | Type | Level | Direction · significance | Rating (1–5) | Status | Evidence | Source |
|---|---|---|---|---|---|---|---|---|
| FGFR3 G697C1 | ||||||||
| (functional) | —UNRESOLVED | Functional | B | Supports Gain Of Function | 2 | accepted | EID10837From a series of 71 oral squamous cell carcinoma (OSCC) samples, 44 showed FGFR3 exon 17 band shift and when sequenced showed G2128T resulting in missense G697C was observed. Blood in 12 of the FGFR3 … (full text at CIViC) PMID 15880580 · Zhang et al., 2005 · Open in CIViC | civic |