Publication
Cyclin D1 overexpression is a negative predictive factor for tamoxifen response in postmenopausal breast cancer patients.
Authors not recorded
Br J Cancer2004PMID 15138475PMC2409465stubpubmedProvenance
- Source
- PubMed
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CIVIC-20260908-000001
Abstract
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Linked entities
Linked entities (3)
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Validated 3
- drugTamoxifencivic_curation1.00
- geneCCND1civic_curation1.00
- variantCCND1 Overexpressioncivic_curation1.00
Curated evidence
Evidence citing this paper (1)
civicProvenance
- Source
- CIViC — Clinical Interpretation of Variants in Cancer
- Dataset
- CIViC evidence items
- Version
- civic-2026-09-08
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- expert curation
- License
- CC0 1.0
- PMID
- 15138475
- Run
- ING-CIVIC-20260908-000001
| Therapy | Cancer | Type | Level | Direction · significance | Rating (1–5) | Status | Evidence | Source |
|---|---|---|---|---|---|---|---|---|
| CCND1 Overexpression1 | ||||||||
| Tamoxifen | Estrogen Receptor-positive Breast CancerUNRESOLVED | Predictive | B | Supports Resistance | 3 | accepted | EID856The authors performed a tissue microarray analysis of 167 postmenopausal breast cancers that had been randomized to treatment with or without tamoxifen. ER +ve patients with high CCND1 tumor expressi… (full text at CIViC) PMID 15138475 · Stendahl et al., 2004 · Open in CIViC | civic |