Loading drug development pipeline…
Loading drug development pipeline…
Derived
For each drug, the most advanced stage supported by registered interventional trials and jurisdiction-aware approval records. Approval in any ingested jurisdiction outranks trial phase; a drug is counted once, at its highest stage.
Computedci-drug-pipeline-v1Stage rulesApprovals feed →
Funnel
Drugs reach Leukemia through trial conditions or approval indications mapped to it or to one of its descendant entities.
26 drugs · 856 active trials
42 drugs · 1,287 active trials
Outside the funnel: Phase not stated 1 · Withdrawn 3. "Withdrawn" = every approval record for the scope is withdrawn or superseded; "phase not stated" = trials exist but none states a phase.
Data updated 15 minutes agoSource updated unknownrecomputed with the intelligence layer
Drugs
Most advanced stage first, then most active trials. Trial counts are interventional studies linking the drug (and, when a cancer is selected, the cancer).
| Drug | Stage | Max phase | Active | Recruiting | Phase 3 | Total trials | Approvals | Jurisdictions | First approval | First trial |
|---|---|---|---|---|---|---|---|---|---|---|
| Cyclophosphamide | Phase 4 | Phase 4 | 174 | 93 | 109 | 725 | 0 | — | — | 1987-08 |
| Cytarabine | Phase 4 | Phase 4 | 151 | 83 | 151 | 766 | 0 | — | — | 1986-11 |
| Dexamethasone | Phase 4 | Phase 4 | 67 | 38 | 58 | 232 | 0 | — | — | 1990-01 |
| Rituximab | Phase 4 | Phase 4 | 61 | 30 | 44 | 307 | 0 | — | — | 1997-09 |
| Daunorubicin | Phase 4 | Phase 4 | 55 | 33 | 79 | 232 | 0 | — | — | 1986-11 |
| Vincristine | Phase 4 | Phase 4 | 55 | 28 | 56 | 228 | 0 | — | — | 1990-01 |
| Ibrutinib | Phase 4 | Phase 4 | 34 | 8 | 22 | 109 | 0 | — | — | 2009-02 |
| Acalabrutinib | Phase 4 | Phase 4 | 33 | 18 | 11 | 46 | 0 | — | — | Jan 30, 2014 |
| Prednisone | Phase 4 | Phase 4 | 32 | 16 | 29 | 121 | 0 | — | — | 1990-01 |
| Etoposide | Phase 4 | Phase 4 | 31 | 12 | 66 | 261 | 0 | — | — | 1990-02 |
| Ruxolitinib | Phase 4 | Phase 4 | 31 | 18 | 2 | 60 | 0 | — | — | May 12, 2008 |
| Doxorubicin | Phase 4 | Phase 4 | 29 | 15 | 38 | 135 | 0 | — | — | 1992-05 |
| Thiotepa | Phase 4 | Phase 4 | 22 | 10 | 8 | 75 | 0 | — | — | 1990-02 |
| Thioguanine | Phase 4 | Phase 4 | 16 | 8 | 39 | 72 | 0 | — | — | 1993-01 |
| Mitoxantrone | Phase 4 | Phase 4 | 15 | 7 | 28 | 137 | 0 | — | — | 1993-01 |
| Bortezomib | Phase 4 | Phase 4 | 15 | 10 | 5 | 78 | 0 | — | — | 1999-11 |
| Prednisolone | Phase 4 | Phase 4 | 10 | 5 | 14 | 33 | 0 | — | — | 1993-01 |
| Tretinoin | Phase 4 | Phase 4 | 7 | 3 | 20 | 52 | 0 | — | — | 1993-01 |
| Ifosfamide | Phase 4 | Phase 4 | 5 | 3 | 12 | 34 | 0 | — | — | 1992-05 |
| Chlorambucil | Phase 4 | Phase 4 | 4 | 0 | 21 | 32 | 0 | — | — | 1999-10 |
| Idelalisib | Phase 4 | Phase 4 | 4 | 2 | 10 | 29 | 0 | — | — | 2008-06 |
| Topotecan | Phase 4 | Phase 4 | 2 | 1 | 0 | 27 | 0 | — | — | 1993-02 |
| Vindesine | Phase 4 | Phase 4 | 2 | 2 | 8 | 13 | 0 | — | — | 1993-01 |
| Panobinostat | Phase 4 | Phase 4 | 1 | 0 | 1 | 20 | 0 | — | — | Mar 1, 2003 |
| Teniposide | Phase 4 | Phase 4 | 0 | 0 | 0 | 9 | 0 | — | — | 1993-01 |
| Amphotericin B | Phase 4 | Phase 4 | 0 | 0 | 1 | 3 | 0 | — | — | 1996-01 |
Stages describe registered activity and ingested regulatory records, not efficacy. Only ingested jurisdictions (currently US and Canada) can place a drug at "approved"; trial phases are as registered by sponsors. Nothing here is a treatment recommendation.