Improving Pre-operative Systemic Therapy for Human Epidermal Growth Factor Receptor 2 (HER2) Amplified Breast Cancer

TERMINATED

Identifier: CI-TRIAL-00054046
Entity page: /trial/NCT03894007 ↗
Edges: 11

Neighbours: 2 cancers9 drugs
Drawn: 11 of 11 neighbours (cap 60); table lists every fetched edge

Accepted: cancer:<slug>, gene:<symbol>, variant:<slug>, drug:<slug>, trial:<NCT id>, or a bare CI id. Find slugs with search.

Most connectedLung Non-Small Cell Carcinoma 3,147 Malignant Colorectal Neoplasm 1,866 ABL1 298 EGFR 276 Imatinib 450 Dasatinib 321

Neighbourhood

Radial view

Focus at the centre; neighbours grouped by entity type. Click a node to re-centre the graph on it; ↗ opens the entity page. Hover a spoke for relationship, evidence level, cancer context and source.

Edges

Every edge, grouped by relationship

Source-native edges first (aggregated per neighbour, direction, evidence level and source), then derived registry links. Up to 15 per relationship (10 trials); “show all” raises one group to 200.

Relationship	Neighbour	Direction	Evidence level	Cancer context	Support	Claim	Source	Expand
Improving Pre-operative Systemic Therapy for Human Epidermal Growth Factor Receptor 2 (HER2) Amplified Breast Cancer condition of …CONDITION_OFderived2 of 2
← condition of	Early Stage Breast Carcinoma registry condition “Early-stage Breast Cancer” mapped ALIAS	—	—	Early Stage Breast Carcinoma	1	Observed	clinicaltrials	graph →
← condition of	HER2-Positive Breast Carcinoma registry condition “HER2-positive Breast Cancer” mapped ALIAS

Improving Pre-operative Systemic Therapy for Human Epidermal Growth Factor Receptor 2 (HER2) Amplified Breast Cancer intervention of …INTERVENTION_OFderived9 of 9
← intervention of	Atezolizumabmonoclonal antibody registry intervention “Atezolizumab” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Carboplatinsmall molecule registry intervention “Carboplatin” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Cyclophosphamidesmall molecule registry intervention “Cyclophosphamide” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Docetaxelsmall molecule registry intervention “Docetaxel” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Epirubicinsmall molecule registry intervention “Epirubicin” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Paclitaxelsmall molecule registry intervention “Paclitaxel” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Pertuzumabmonoclonal antibody registry intervention “Pertuzumab” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Trastuzumabmonoclonal antibody registry intervention “Trastuzumab” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Trastuzumab Emtansineadc registry intervention “Trastuzumab emtansine” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →

Improving Pre-operative Systemic Therapy for Human Epidermal Growth Factor Receptor 2 (HER2) Amplified Breast Cancer intervention of …INTERVENTION_OFderived9 of 9

← intervention of

Atezolizumabmonoclonal antibody

registry intervention “Atezolizumab” (DRUG) mapped ALIAS

—

not mapped

Observed

clinicaltrials

graph →

← intervention of

Carboplatinsmall molecule

registry intervention “Carboplatin” (DRUG) mapped ALIAS

—