TAPUR: Testing the Use of Food and Drug Administration (FDA) Approved Drugs That Target a Specific Abnormality in a Tumor Gene in People With Advanced Stage Cancer

RECRUITING

Identifier: CI-TRIAL-00125003
Entity page: /trial/NCT02693535 ↗
Edges: 9

Neighbours: 3 cancers6 drugs
Drawn: 9 of 9 neighbours (cap 60); table lists every fetched edge

Accepted: cancer:<slug>, gene:<symbol>, variant:<slug>, drug:<slug>, trial:<NCT id>, or a bare CI id. Find slugs with search.

Most connectedLung Non-Small Cell Carcinoma 3,149 Malignant Colorectal Neoplasm 1,866 ABL1 298 EGFR 276 Imatinib 450 Dasatinib 321

Neighbourhood

Radial view

Focus at the centre; neighbours grouped by entity type. Click a node to re-centre the graph on it; ↗ opens the entity page. Hover a spoke for relationship, evidence level, cancer context and source.

Edges

Every edge, grouped by relationship

Source-native edges first (aggregated per neighbour, direction, evidence level and source), then derived registry links. Up to 15 per relationship (10 trials); “show all” raises one group to 200.

Relationship	Neighbour	Direction	Evidence level	Cancer context	Support	Claim	Source	Expand
TAPUR: Testing the Use of Food and Drug Administration (FDA) Approved Drugs That Target a Specific Abnormality in a Tumor Gene in People With Advanced Stage Cancer condition of …CONDITION_OFderived3 of 3
← condition of	Multiple Myeloma registry condition “Multiple Myeloma” mapped CURATED_EXACT	—	—	Multiple Myeloma	1	Observed	clinicaltrials	graph →
← condition of	Non-Hodgkin Lymphoma registry condition “Lymphoma, Non-Hodgkin” mapped ALIAS	—

TAPUR: Testing the Use of Food and Drug Administration (FDA) Approved Drugs That Target a Specific Abnormality in a Tumor Gene in People With Advanced Stage Cancer intervention of …INTERVENTION_OFderived6 of 6
← intervention of	Abemaciclibsmall molecule registry intervention “Abemaciclib (CLOSED TO ENROLLMENT)” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Dabrafenib/Trametinib Regimen registry intervention “Dabrafenib plus Trametinib” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Futibatinibsmall molecule registry intervention “Futibatinib” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Olaparibsmall molecule registry intervention “Olaparib (CLOSED TO ENROLLMENT)” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Sunitinibsmall molecule registry intervention “Sunitinib (CLOSED TO ENROLLMENT)” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Talazoparibsmall molecule registry intervention “Talazoparib (CLOSED TO ENROLLMENT)” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →

TAPUR: Testing the Use of Food and Drug Administration (FDA) Approved Drugs That Target a Specific Abnormality in a Tumor Gene in People With Advanced Stage Cancer intervention of …INTERVENTION_OFderived6 of 6

← intervention of

Abemaciclibsmall molecule

registry intervention “Abemaciclib (CLOSED TO ENROLLMENT)” (DRUG) mapped ALIAS

—

not mapped

Observed

clinicaltrials

graph →

← intervention of

Dabrafenib/Trametinib Regimen

registry intervention “Dabrafenib plus Trametinib” (DRUG) mapped ALIAS

—